1ELC
| Analogous inhibitors of elastase do not always bind analogously | 分子名称: | 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-phenylalaninamide, CALCIUM ION, ELASTASE | 著者 | Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D. | 登録日 | 1993-12-07 | 公開日 | 1994-04-30 | 最終更新日 | 2012-12-12 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Analogous inhibitors of elastase do not always bind analogously. Nat.Struct.Biol., 1, 1994
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1EOV
| FREE ASPARTYL-TRNA SYNTHETASE (ASPRS) (E.C. 6.1.1.12) FROM YEAST | 分子名称: | ASPARTYL-TRNA SYNTHETASE | 著者 | Sauter, C, Lorber, B, Cavarelli, J, Moras, D, Giege, R. | 登録日 | 2000-03-24 | 公開日 | 2000-09-24 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain. J.Mol.Biol., 299, 2000
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1EYL
| STRUCTURE OF A RECOMBINANT WINGED BEAN CHYMOTRYPSIN INHIBITOR | 分子名称: | CHYMOTRYPSIN INHIBITOR, SULFATE ION | 著者 | Dattagupta, J.K, Chakrabarti, C, Ravichandran, S, Ghosh, S. | 登録日 | 2000-05-07 | 公開日 | 2000-05-24 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: crystal structures of two point mutants Asn14-->Lys and Asn14-->Asp. Protein Eng., 14, 2001
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1ERC
| THE NMR SOLUTION STRUCTURE OF THE PHEROMONE ER-1 FROM THE CILIATED PROTOZOAN EUPLOTES RAIKOVI | 分子名称: | PHEROMONE ER-1 | 著者 | Mronga, S, Luginbuhl, P, Brown, L.R, Ortenzi, C, Luporini, P, Bradshaw, R.A, Wuthrich, K. | 登録日 | 1994-02-14 | 公開日 | 1994-10-15 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | The NMR solution structure of the pheromone Er-1 from the ciliated protozoan Euplotes raikovi. Protein Sci., 3, 1994
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1ELB
| Analogous inhibitors of elastase do not always bind analogously | 分子名称: | 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-leucinamide, CALCIUM ION, ELASTASE, ... | 著者 | Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D. | 登録日 | 1993-12-07 | 公開日 | 1994-06-22 | 最終更新日 | 2012-12-12 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Analogous inhibitors of elastase do not always bind analogously. Nat.Struct.Biol., 1, 1994
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1EEA
| Acetylcholinesterase | 分子名称: | PROTEIN (ACETYLCHOLINESTERASE) | 著者 | Raves, M.L, Giles, K, Schrag, J.D, Schmid, M.F, Phillips Jr, G.N, Wah, C, Howard, A.J, Silman, I, Sussman, J.L. | 登録日 | 1999-01-26 | 公開日 | 1999-02-01 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | Quaternary Structure of Tetrameric Acetylcholinesterase Structure and Function of Cholinesterases and Related Proteins, 1998
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1ELA
| Analogous inhibitors of elastase do not always bind analogously | 分子名称: | 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-prolinamide, ACETIC ACID, CALCIUM ION, ... | 著者 | Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D. | 登録日 | 1993-12-07 | 公開日 | 1994-04-30 | 最終更新日 | 2012-12-12 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Analogous inhibitors of elastase do not always bind analogously. Nat.Struct.Biol., 1, 1994
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4U7D
| Structure of human RECQ-like helicase in complex with an oligonucleotide | 分子名称: | ATP-dependent DNA helicase Q1, DNA oligonucleotide, ZINC ION | 著者 | Pike, A.C.W, Zhang, Y, Schnecke, C, Cooper, C.D.O, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC) | 登録日 | 2014-07-30 | 公開日 | 2015-01-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: Insights from DNA complex structures. Proc.Natl.Acad.Sci.USA, 112, 2015
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4V0S
| Crystal structure of Mycobacterium tuberculosis Type II Dehydroquinase D88N mutant inhibited by a 3-dehydroquinic acid derivative | 分子名称: | (1R,2S,4S,5R)-2-(2,3,4,5,6-pentafluorophenyl)methyl-1,4,5-trihydroxy-3-oxocyclohexane-1-carboxylic acid, 3,4-DIHYDROXY-2-[(2,3,4,5,6-PENTAFLUOROPHENYL)METHYL]BENZOIC ACID, 3-DEHYDROQUINATE DEHYDRATASE, ... | 著者 | Otero, J.M, Llamas-Saiz, A.L, Santiago, C, Lamb, H, Hawkins, A.R, Maneiro, M, Peon, A, Gonzalez-Bello, C, van Raaij, M.J. | 登録日 | 2014-09-18 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Investigation of the Dehydratation Mechanism Catalyzed by the Type II Dehydroquinase To be Published
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4URV
| The crystal structure of H-Ras and SOS in complex with ligands | 分子名称: | 4-(4-BROMOPHENYL)PIPERIDIN-4-OL, FORMIC ACID, GTPASE HRAS, ... | 著者 | Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. | 登録日 | 2014-07-02 | 公開日 | 2015-03-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
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4UU9
| Crystal structure of the human c5a in complex with MEDI7814 a neutralising antibody | 分子名称: | COMPLEMENT C5, MEDI7814, SULFATE ION | 著者 | Colley, C, Sridharan, S, Dobson, C, Popovic, B, Debreczeni, J.E, Hargreaves, D, Edwards, B, Brennan, J, England, L, Fung, S, An Eghobamien, L, Sivars, U, Woods, R, Flavell, L, Renshaw, G.J, Wickson, K, Wilkinson, T, Davies, R, Bonnell, J, Warrener, P, Howes, R, Vaughan, T. | 登録日 | 2014-07-25 | 公開日 | 2015-08-12 | 最終更新日 | 2019-02-27 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors. MAbs, 10, 2018
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8USO
| Full-length human CaMKII delta holoenzyme | 分子名称: | MALONATE ION, calcium/calmodulin-dependent protein kinase | 著者 | Ozden, C, Abromson, N.L, Tomchick, D.R, Stratton, M.M, Garman, S.C. | 登録日 | 2023-10-28 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Full-length human CaMKII delta holoenzyme To be published
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8VSW
| 4-MERCAPTOPHENOL-ALPHA3C | 分子名称: | 4-mercaptophenol-alpha3C protein, 4-sulfanylphenol | 著者 | Tommos, C. | 登録日 | 2024-01-24 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Switching the proton-coupled electron transfer mechanism for non-canonical tyrosine residues in a de novo protein. Chem Sci, 15, 2024
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8W3V
| Crystal structure of human WDR41 | 分子名称: | WD repeat-containing protein 41 | 著者 | Hutchinson, A, Dong, A, Li, Y, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | 登録日 | 2024-02-22 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of human WDR41 To be published
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8V3B
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8WUC
| Cryo-EM structure of H. thermoluteolus GroEL-GroES2 football complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | 登録日 | 2023-10-20 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural insights into thermophilic chaperonin complexes. Structure, 2024
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8VJC
| Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation. | 分子名称: | Insulin-like growth factor II, Isoform Short of Insulin receptor | 著者 | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | 登録日 | 2024-01-06 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8WUW
| Cryo-EM structure of H. thermophilus GroEL-GroES2 asymmetric football complex | 分子名称: | Chaperonin GroEL, Co-chaperonin GroES, MAGNESIUM ION, ... | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | 登録日 | 2023-10-21 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into thermophilic chaperonin complexes. Structure, 2024
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8WU4
| Cryo-EM structure of native H. thermoluteolus TH-1 GroEL | 分子名称: | Chaperonin GroEL | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | 登録日 | 2023-10-20 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into thermophilic chaperonin complexes. Structure, 2024
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8WUX
| Cryo-EM structure of H. thermophilus GroEL-GroES bullet complex | 分子名称: | Chaperonin GroEL, Co-chaperonin GroES, MAGNESIUM ION, ... | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | 登録日 | 2023-10-21 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into thermophilic chaperonin complexes. Structure, 2024
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8WU1
| Cryo-EM structure of CB1-beta-arrestin1 complex | 分子名称: | Beta-arrestin-1, Cannabinoid receptor 1,Vasopressin V2 receptor, Fab30 heavy chain, ... | 著者 | Liao, Y, Zhang, H, Shen, Q, Cai, C. | 登録日 | 2023-10-19 | 公開日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of CB1-beta-arrestin1 complex to be published
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8VJB
| Cryo-EM structure of short form insulin receptor (IR-A) with four IGF2 bound, symmetric conformation. | 分子名称: | Insulin-like growth factor II, Isoform Short of Insulin receptor | 著者 | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | 登録日 | 2024-01-06 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8WQA
| Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1) | 分子名称: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Chen, X, Zhang, K, Xu, C. | 登録日 | 2023-10-11 | 公開日 | 2024-04-03 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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8WQE
| Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 1) | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | 著者 | Chen, X, Zhang, K, Xu, C. | 登録日 | 2023-10-11 | 公開日 | 2024-04-03 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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8WQC
| cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1 | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | 著者 | Chen, X, Zhang, K, Xu, C. | 登録日 | 2023-10-11 | 公開日 | 2024-04-03 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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