4AUT
| Crystal structure of the tuberculosis drug target Decaprenyl- Phosphoryl-beta-D-Ribofuranose-2-oxidoreductase (DprE1) from Mycobacterium smegmatis | 分子名称: | DECAPRENYL-PHOSPHORYL-BETA-D-RIBOFURANOSE-2-OXIDOREDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Neres, J, Pojer, F, Molteni, E, Chiarelli, L.R, Dhar, N, Boy-Rottger, S, Buroni, S, Fullam, E, Degiacomi, G, Lucarelli, A, Read, R.J, Zanoni, G, Edmondson, D.E, De Rossi, E, Pasca, M, Riccardi, G, Mattevi, A, Dyson, P.J, Cole, S.T, Binda, C. | 登録日 | 2012-05-21 | 公開日 | 2012-09-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium Tuberculosis. Sci. Transl. Med., 4, 2012
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5FUS
| Crystal structure of B. cenocepacia DfsA | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, GLYCEROL, LAURIC ACID, ... | 著者 | Spadaro, F, Scoffone, V.C, Chiarelli, L.R, Fumagalli, M, Buroni, S, Riccardi, G, Forneris, F. | 登録日 | 2016-01-29 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | The Crystal Structure of Burkholderia Cenocepacia Dfsa Provides Insights Into Substrate Recognition and Quorum Sensing Fatty Acid Biosynthesis. Biochemistry, 55, 2016
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2V57
| Crystal structure of the TetR-like transcriptional regulator LfrR from Mycobacterium smegmatis in complex with proflavine | 分子名称: | ISOPROPYL ALCOHOL, PROFLAVIN, SULFATE ION, ... | 著者 | Bellinzoni, M, Buroni, S, Riccardi, G, De Rossi, E, Alzari, P.M. | 登録日 | 2008-10-02 | 公開日 | 2009-10-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Plasticity and Distinct Drug-Binding Modes of Lfrr, a Mycobacterial Efflux Pump Regulator. J.Bacteriol., 191, 2009
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2WGB
| Crystal structure of the TetR-like transcriptional regulator LfrR from Mycobacterium smegmatis | 分子名称: | SULFATE ION, TETR FAMILY TRANSCRIPTIONAL REPRESSOR LFRR | 著者 | Bellinzoni, M, Buroni, S, Riccardi, G, De Rossi, E, Alzari, P.M. | 登録日 | 2009-04-16 | 公開日 | 2009-10-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Plasticity and Distinct Drug-Binding Modes of Lfrr, a Mycobacterial Efflux Pump Regulator. J.Bacteriol., 191, 2009
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2WZW
| Crystal structure of the FMN-dependent nitroreductase NfnB from Mycobacterium smegmatis in complex with NADPH | 分子名称: | FLAVIN MONONUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NFNB PROTEIN, ... | 著者 | Bellinzoni, M, Manina, G, Riccardi, G, Alzari, P.M. | 登録日 | 2009-12-03 | 公開日 | 2010-07-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Biological and Structural Characterization of the Mycobacterium Smegmatis Nitroreductase Nfnb, and its Role in Benzothiazinone Resistance Mol.Microbiol., 77, 2010
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4NXI
| Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Uncharacterized protein | 著者 | Albesa-Jove, D, Urresti, S, Comino, N, Guerin, M.E. | 登録日 | 2013-12-09 | 公開日 | 2014-10-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. Acs Chem.Biol., 9, 2014
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4F4Q
| Crystal structure of M. smegmatis DprE1 in complex with FAD and covalently bound BTZ043 | 分子名称: | 8-(hydroxyamino)-2-[(2S)-2-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one, DprE1, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Neres, J, Pojer, F, Molteni, E, Chiarelli, L, Riccardi, G, Mattevi, A, Cole, S.T, Binda, C. | 登録日 | 2012-05-11 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.619 Å) | 主引用文献 | Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. Sci Transl Med, 4, 2012
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2WZV
| Crystal structure of the FMN-dependent nitroreductase NfnB from Mycobacterium smegmatis | 分子名称: | FLAVIN MONONUCLEOTIDE, GLYCEROL, NFNB PROTEIN, ... | 著者 | Bellinzoni, M, Manina, G, Riccardi, G, Alzari, P.M. | 登録日 | 2009-12-03 | 公開日 | 2010-07-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Biological and Structural Characterization of the Mycobacterium Smegmatis Nitroreductase Nfnb, and its Role in Benzothiazinone Resistance Mol.Microbiol., 77, 2010
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