9N6B
 
 | | Structure of the retron IA complex with HNH nuclease in the "up" orientation | | Descriptor: | AAA family ATPase, ADENOSINE-5'-TRIPHOSPHATE, RNA-directed DNA polymerase, ... | | Authors: | Burman, N, Thomas-George, J, Wilkinson, R, Wiedenheft, B. | | Deposit date: | 2025-02-05 | | Release date: | 2025-04-23 | | Last modified: | 2025-11-12 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structural basis of antiphage defence by an ATPase-associated reverse transcriptase.
Nat Commun, 16, 2025
|
|
9N69
 | | Structure of the retron IA complex with HNH nuclease in the "down" orientation | | Descriptor: | AAA family ATPase, ADENOSINE-5'-TRIPHOSPHATE, RNA-directed DNA polymerase, ... | | Authors: | Burman, N, Thomas-George, J, Wilkinson, R, Wiedenheft, B. | | Deposit date: | 2025-02-05 | | Release date: | 2025-04-23 | | Last modified: | 2025-11-12 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | Structural basis of antiphage defence by an ATPase-associated reverse transcriptase.
Nat Commun, 16, 2025
|
|
9N6C
 | | Structure of the Retron IA Complex without the HNH Nuclease | | Descriptor: | AAA family ATPase, ADENOSINE-5'-TRIPHOSPHATE, RNA-directed DNA polymerase, ... | | Authors: | Burman, N, Thomas-George, J, Wilkinson, R, Wiedenheft, B. | | Deposit date: | 2025-02-05 | | Release date: | 2025-04-23 | | Last modified: | 2025-11-12 | | Method: | ELECTRON MICROSCOPY (2.99 Å) | | Cite: | Structural basis of antiphage defence by an ATPase-associated reverse transcriptase.
Nat Commun, 16, 2025
|
|
9ARW
 | | Structure of the guideless DtCmr Type III CRISPR complex | | Descriptor: | CRISPR type III-B/RAMP module-associated protein Cmr5, CSD domain-containing protein Cmr6, Type III-B CRISPR module RAMP protein Cmr4, ... | | Authors: | Burman, N, Henriques, W.H, Pandey, S, Wiedenheft, B. | | Deposit date: | 2024-02-23 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure of a type III CRISPR complex that AMPylates a HEPN toxin
To Be Published
|
|
9NLX
 | | Cryo-EM structure of the trimeric SenDRT9 RT-ncRNA complex (GST fusion) | | Descriptor: | RNA (147-MER), RNA-dependent DNA polymerase | | Authors: | Burman, N, Pandey, S, Wiedenheft, B, Sternberg, S.H. | | Deposit date: | 2025-03-03 | | Release date: | 2025-05-14 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Protein-primed homopolymer synthesis by an antiviral reverse transcriptase.
Nature, 643, 2025
|
|
9NLV
 | | Cryo-EM structure of hexameric SenDRT9 RT-ncRNA complex | | Descriptor: | RNA (147-MER), RNA-dependent DNA polymerase | | Authors: | Burman, N, Pandey, S, Wiedenheft, B, Sternberg, S.H. | | Deposit date: | 2025-03-03 | | Release date: | 2025-05-14 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Protein-primed homopolymer synthesis by an antiviral reverse transcriptase.
Nature, 643, 2025
|
|
6VJG
 | | Csx3-I222 Crystal Form at 1.8 Angstrom Resolution | | Descriptor: | CRISPR-associated protein, Csx3 family | | Authors: | Brown, S, Charbonneau, A, Burman, N, Gauvin, C.C, Lawrence, C.M. | | Deposit date: | 2020-01-15 | | Release date: | 2020-09-02 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Csx3 is a cyclic oligonucleotide phosphodiesterase associated with type III CRISPR-Cas that degrades the second messenger cA 4 .
J.Biol.Chem., 295, 2020
|
|
8UX9
 | | Asymmetric unit of the PARIS Immune Complex at 3.2 Angstrom Resolution | | Descriptor: | AriA, AriB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | Authors: | Burman, N.B, Henriques, W, Wilkinson, R, Graham, A, Wiedenheft, B. | | Deposit date: | 2023-11-09 | | Release date: | 2024-09-18 | | Last modified: | 2025-04-02 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | A virally encoded tRNA neutralizes the PARIS antiviral defence system.
Nature, 634, 2024
|
|
