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1EJ4
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COCRYSTAL STRUCTURE OF EIF4E/4E-BP1 PEPTIDE
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, EUKARYOTIC INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E BINDING PROTEIN 1
Authors:Marcotrigiano, J, Gingras, A.-C, Sonenberg, N, Burley, S.K.
Deposit date:2000-02-28
Release date:2000-03-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G.
Mol.Cell, 3, 1999
1G61
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CRYSTAL STRUCTURE OF M.JANNASCHII EIF6
Descriptor: TRANSLATION INITIATION FACTOR 6
Authors:Groft, C.M, Beckmann, R, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2000-11-02
Release date:2000-11-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structures of ribosome anti-association factor IF6.
Nat.Struct.Biol., 7, 2000
1I9A
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BU of 1i9a by Molmil
STRUCTURAL STUDIES OF CHOLESTEROL BIOSYNTHESIS: MEVALONATE 5-DIPHOSPHATE DECARBOXYLASE AND ISOPENTENYL DIPHOSPHATE ISOMERASE
Descriptor: ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE, MANGANESE (II) ION
Authors:Bonanno, J.B, Edo, C, Eswar, N, Pieper, U, Romanowski, M.J, Ilyin, V, Gerchman, S.E, Kycia, H, Studier, F.W, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-03-18
Release date:2001-03-28
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural genomics of enzymes involved in sterol/isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 98, 2001
1I27
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BU of 1i27 by Molmil
CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RAP74 SUBUNIT OF HUMAN TRANSCRIPTION FACTOR IIF (TFIIF)
Descriptor: TRANSCRIPTION FACTOR IIF, ZINC ION
Authors:Kamada, K, De Angelis, J, Roeder, R.G, Burley, S.K.
Deposit date:2001-02-07
Release date:2001-03-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:Crystal structure of the C-terminal domain of the RAP74 subunit of human transcription factor IIF.
Proc.Natl.Acad.Sci.USA, 98, 2001
1JFI
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Crystal Structure of the NC2-TBP-DNA Ternary Complex
Descriptor: 5'-D(*G*GP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*C)-3', TATA-BOX-BINDING PROTEIN (TBP), ...
Authors:Kamada, K, Shu, F, Chen, H, Malik, S, Stelzer, G, Roeder, R.G, Meisterernst, M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-06-20
Release date:2001-07-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex.
Cell(Cambridge,Mass.), 106, 2001
1JG8
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BU of 1jg8 by Molmil
Crystal Structure of Threonine Aldolase (Low-specificity)
Descriptor: CALCIUM ION, L-allo-threonine aldolase, SODIUM ION
Authors:Kielkopf, C.L, Bonanno, J, Ray, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-06-23
Release date:2001-07-04
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Low-specificity Threonine Aldolase, a Key Enzyme in Glycine Biosynthesis
To be published
1JD1
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Crystal Structure of YEO7_yeast
Descriptor: HYPOTHETICAL 13.9 KDA PROTEIN IN FCY2-PET117 INTERGENIC REGION
Authors:Deaconescu, A.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-06-12
Release date:2001-07-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray structure of Saccharomyces cerevisiae homologous mitochondrial matrix factor 1 (Hmf1).
Proteins, 48, 2002
1JYH
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BU of 1jyh by Molmil
Crystal Structure of the Escherichia coli SbmC protein (AKA Gyrase Inhibitory Protein GyrI, AKA YeeB)
Descriptor: DNA Gyrase inhibitory protein
Authors:Romanowski, M.J, Gibney, S.A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-09-12
Release date:2002-04-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Escherichia coli SbmC protein that protects cells from the DNA replication inhibitor microcin B17.
Proteins, 47, 2002
1JR7
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CRYSTAL STRUCTURE OF GAB REVEALS OXIDOREDUCTASE FOLD
Descriptor: FE (II) ION, HYPOTHETICAL 37.4 KDA PROTEIN IN ILEY-GABD INTERGENIC REGION
Authors:Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-08-12
Release date:2001-08-22
Last modified:2023-02-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural genomics: a pipeline for providing structures for the biologist.
Protein Sci., 11, 2002
1JSS
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BU of 1jss by Molmil
Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4).
Descriptor: cholesterol-regulated START protein 4
Authors:Romanowski, M.J, Soccio, R.E, Breslow, J.L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-08-17
Release date:2002-04-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain.
Proc.Natl.Acad.Sci.USA, 99, 2002
1JSX
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Crystal Structure of the Escherichia coli Glucose-Inhibited Division Protein B (GidB)
Descriptor: Glucose-inhibited division protein B
Authors:Romanowski, M.J, Bonanno, J.B, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-08-19
Release date:2002-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold.
Proteins, 47, 2002
1JMT
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X-ray Structure of a Core U2AF65/U2AF35 Heterodimer
Descriptor: HEXANE-1,6-DIOL, SPLICING FACTOR U2AF 35 KDA SUBUNIT, SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Kielkopf, C.L, Rodionova, N.A, Green, M.R, Burley, S.K.
Deposit date:2001-07-19
Release date:2001-09-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer.
Cell(Cambridge,Mass.), 106, 2001
1HU3
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BU of 1hu3 by Molmil
MIDDLE DOMAIN OF HUMAN EIF4GII
Descriptor: EIF4GII
Authors:Marcotrigiano, J, Lomakin, I, Pestova, T.V, Hellen, C.U.T, Sonenberg, N, Burley, S.K.
Deposit date:2001-01-03
Release date:2001-02-21
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery.
Mol.Cell, 7, 2001
1KAG
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BU of 1kag by Molmil
Crystal Structure of the Escherichia coli Shikimate Kinase I (AroK)
Descriptor: Shikimate kinase I
Authors:Romanowski, M.J, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-11-01
Release date:2002-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of the Escherichia coli shikimate kinase I (AroK) that confers sensitivity to mecillinam.
Proteins, 47, 2002
1K47
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Crystal Structure of the Streptococcus pneumoniae Phosphomevalonate Kinase (PMK)
Descriptor: phosphomevalonate kinase
Authors:Romanowski, M.J, Bonanno, J.B, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-10-05
Release date:2002-05-08
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Crystal structure of the Streptococcus pneumoniae phosphomevalonate kinase, a member of the GHMP kinase superfamily.
Proteins, 47, 2002
1KUV
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BU of 1kuv by Molmil
X-ray Crystallographic Studies of Serotonin N-acetyltransferase Catalysis and Inhibition
Descriptor: COA-S-ACETYL 5-BROMOTRYPTAMINE, MAGNESIUM ION, Serotonin N-acetyltransferase
Authors:Wolf, E, De Angelis, J, Khalil, E.M, Cole, P.A, Burley, S.K.
Deposit date:2002-01-22
Release date:2002-03-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray crystallographic studies of serotonin N-acetyltransferase catalysis and inhibition.
J.Mol.Biol., 317, 2002
1KCX
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X-ray structure of NYSGRC target T-45
Descriptor: DIHYDROPYRIMIDINASE RELATED PROTEIN-1
Authors:Deo, R.C, Schmidt, E.F, Strittmatter, S.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-11-11
Release date:2003-08-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural bases for CRMP function in plexin-dependent semaphorin3A signaling
Embo J., 23, 2004
1I2T
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BU of 1i2t by Molmil
X-RAY STRUCTURE OF THE HUMAN HYPERPLASTIC DISCS PROTEIN: AN ORTHOLOG OF THE C-TERMINAL DOMAIN OF POLY(A)-BINDING PROTEIN
Descriptor: HYD PROTEIN
Authors:Deo, R.C, Sonenberg, N, Burley, S.K.
Deposit date:2001-02-12
Release date:2001-04-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:X-ray structure of the human hyperplastic discs protein: an ortholog of the C-terminal domain of poly(A)-binding protein.
Proc.Natl.Acad.Sci.USA, 98, 2001
1KU9
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X-ray Structure of a Methanococcus jannaschii DNA-Binding Protein: Implications for Antibiotic Resistance in Staphylococcus aureus
Descriptor: hypothetical protein MJ223
Authors:Ray, S.S, Bonanno, J.B, Chen, H, de Lencastre, H, Wu, S, Tomasz, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2002-01-21
Release date:2002-12-25
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray structure of an M. jannaschii DNA-binding protein: implications for antibiotic resistance in S. aureus
Proteins, 50, 2002
1KUX
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X-ray Crystallographic Studies of Serotonin N-acetyltransferase Catalysis and Inhibition
Descriptor: COA-S-TRIMETHYLENE-ACETYL-TRYPTAMINE, Serotonin N-acetyltransferase
Authors:Wolf, E, De Angelis, J, Khalil, E.M, Cole, P.A, Burley, S.K.
Deposit date:2002-01-22
Release date:2002-03-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic studies of serotonin N-acetyltransferase catalysis and inhibition.
J.Mol.Biol., 317, 2002
1KNZ
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Recognition of the rotavirus mRNA 3' consensus by an asymmetric NSP3 homodimer
Descriptor: 5'-R(*UP*GP*AP*CP*C)-3', Nonstructural RNA-binding Protein 34
Authors:Deo, R.C, Groft, C.M, Rajashankar, K.R, Burley, S.K.
Deposit date:2001-12-19
Release date:2002-01-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Recognition of the rotavirus mRNA 3' consensus by an asymmetric NSP3 homodimer.
Cell(Cambridge,Mass.), 108, 2002
1KUY
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X-ray Crystallographic Studies of Serotonin N-acetyltransferase Catalysis and Inhibition
Descriptor: COA-S-ACETYL TRYPTAMINE, Serotonin N-acetyltransferase
Authors:Wolf, E, De Angelis, J, Khalil, E.M, Cole, P.A, Burley, S.K.
Deposit date:2002-01-22
Release date:2002-03-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray crystallographic studies of serotonin N-acetyltransferase catalysis and inhibition.
J.Mol.Biol., 317, 2002
1LJ2
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Recognition of eIF4G by Rotavirus NSP3 reveals a basis for mRNA circularization
Descriptor: GOLD ION, NONSTRUCTURAL RNA-BINDING PROTEIN 34, eukaryotic protein synthesis initiation factor
Authors:Groft, C.M, Burley, S.K.
Deposit date:2002-04-18
Release date:2002-07-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Recognition of eIF4G by rotavirus NSP3 reveals a basis for mRNA circularization.
Mol.Cell, 9, 2002
1ZY4
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Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant in Apo Form.
Descriptor: GLYCEROL, Serine/threonine-protein kinase GCN2
Authors:Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K.
Deposit date:2005-06-09
Release date:2005-06-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005
1ZYC
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Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type in Apo Form.
Descriptor: Serine/threonine-protein kinase GCN2
Authors:Padyana, A.K, Qiu, H, Roll-Mecak, A, Hinnebusch, A.G, Burley, S.K.
Deposit date:2005-06-09
Release date:2005-06-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem., 280, 2005

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