1KUX

X-ray Crystallographic Studies of Serotonin N-acetyltransferase Catalysis and Inhibition

Summary for 1KUX

Related1BO4 1B6B 1CJW 1KUV 1KUY
DescriptorSerotonin N-acetyltransferase, COA-S-TRIMETHYLENE-ACETYL-TRYPTAMINE (3 entities in total)
Functional Keywordsenzyme-inhibitor complex, bisubstrate analog, alternate conformations, transferase
Biological sourceOvis aries (sheep)
Cellular locationCytoplasm (By similarity) Q29495
Total number of polymer chains1
Total molecular weight24121.42
Authors
Wolf, E.,De Angelis, J.,Khalil, E.M.,Cole, P.A.,Burley, S.K. (deposition date: 2002-01-22, release date: 2002-03-22, Last modification date: 2011-07-13)
Primary citation
Wolf, E.,De Angelis, J.,Khalil, E.M.,Cole, P.A.,Burley, S.K.
X-ray crystallographic studies of serotonin N-acetyltransferase catalysis and inhibition.
J.Mol.Biol., 317:215-224, 2002
PubMed: 11902838 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.2001.5371
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers130.6%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
168889
PDB entries from 2020-09-16