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1YGC
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BU of 1ygc by Molmil
Short Factor VIIa with a small molecule inhibitor
分子名称: (R)-4-[2-(3-AMINO-BENZENESULFONYLAMINO)-1-(3,5-DIETHOXY-2-FLUOROPHENYL)-2-OXO-ETHYLAMINO]-2-HYDROXY-BENZAMIDINE, CALCIUM ION, Coagulation factor VII, ...
著者Olivero, A.G, Eigenbrot, C, Goldsmith, R, Robarge, K, Artis, D.R, Flygare, J, Rawson, T, Refino, C, Bunting, S, Kirchhofer, D.
登録日2005-01-04
公開日2005-01-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo.
J.Biol.Chem., 280, 2005
1JPS
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BU of 1jps by Molmil
Crystal structure of tissue factor in complex with humanized Fab D3h44
分子名称: immunoglobulin Fab D3H44, heavy chain, light chain, ...
著者Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A.
登録日2001-08-03
公開日2002-02-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001
1JPT
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BU of 1jpt by Molmil
Crystal Structure of Fab D3H44
分子名称: immunoglobulin Fab D3H44, heavy chain, immunoglobulin Fab D3h44, ...
著者Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A.
登録日2001-08-03
公開日2002-02-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001

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件を2024-05-15に公開中

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