5CRO
 
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4HF1
 | | Crystal Structure of IscR bound to its promoter | | Descriptor: | DNA (29-MER), HTH-type transcriptional regulator IscR | | Authors: | Rajagopalan, S.R, Phillips, K.J. | | Deposit date: | 2012-10-04 | | Release date: | 2013-05-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.222 Å) | | Cite: | Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity.
Nat.Struct.Mol.Biol., 20, 2013
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4JRI
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4JUV
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4JLI
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4JRK
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2GCT
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2G0E
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3DNU
 | | structure of MDT protein | | Descriptor: | CHLORIDE ION, PHOSPHATE ION, Protein hipA | | Authors: | schumacher, M.A. | | Deposit date: | 2008-07-02 | | Release date: | 2009-01-27 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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3DNT
 | | structures of MDT proteins | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein hipA, ... | | Authors: | Schumacher, M.A. | | Deposit date: | 2008-07-02 | | Release date: | 2009-01-27 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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3DNV
 | | MDT Protein | | Descriptor: | DNA (5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3'), HTH-type transcriptional regulator hipB, Protein hipA, ... | | Authors: | schumacher, M.A. | | Deposit date: | 2008-07-02 | | Release date: | 2009-01-27 | | Last modified: | 2023-04-05 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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3FBR
 | | structure of HipA-amppnp-peptide | | Descriptor: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase toxin HipA, peptide of EF-Tu | | Authors: | Schumacher, M.A. | | Deposit date: | 2008-11-19 | | Release date: | 2009-02-10 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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3GCT
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3HZI
 | | Structure of mdt protein | | Descriptor: | 5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3', ADENOSINE-5'-TRIPHOSPHATE, HTH-type transcriptional regulator hipB, ... | | Authors: | Schumacher, M.A. | | Deposit date: | 2009-06-23 | | Release date: | 2009-07-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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1KNX
 | | HPr kinase/phosphatase from Mycoplasma pneumoniae | | Descriptor: | Probable HPr(Ser) kinase/phosphatase | | Authors: | Allen, G.S. | | Deposit date: | 2001-12-19 | | Release date: | 2002-12-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of HPr Kinase/Phosphatase from Mycoplasma pneumoniae
J.Mol.Biol., 326, 2003
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1LBG
 | | LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY | | Descriptor: | DNA (5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), PROTEIN (LACTOSE OPERON REPRESSOR) | | Authors: | Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P. | | Deposit date: | 1996-01-03 | | Release date: | 1996-02-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (4.8 Å) | | Cite: | Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
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1LBH
 | | INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG | | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG | | Authors: | Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P. | | Deposit date: | 1996-02-17 | | Release date: | 1996-07-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
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1LBI
 | | LAC REPRESSOR | | Descriptor: | LAC REPRESSOR | | Authors: | Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P. | | Deposit date: | 1996-02-17 | | Release date: | 1996-07-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
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1QB8
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5TZF
 | | Structure of the BldD CTD(D116A)-(c-di-GMP)2 intermediate, form 1 | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein | | Authors: | Schumacher, M.A. | | Deposit date: | 2016-11-21 | | Release date: | 2017-04-19 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
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5TZD
 | | Structure of the WT S. venezulae BldD-(CTD-c-di-GMP)2 assembly intermediate | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein | | Authors: | Schumacher, M. | | Deposit date: | 2016-11-21 | | Release date: | 2017-04-19 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.749 Å) | | Cite: | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
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5TZG
 | | Structure of the BldD CTD(D116A)-(c-di-GMP)2, form 2 | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein, ZINC ION | | Authors: | Schumacher, M.A. | | Deposit date: | 2016-11-21 | | Release date: | 2017-04-19 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
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1GCT
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1HXD
 | | CRYSTAL STRUCTURE OF E. COLI BIOTIN REPRESSOR WITH BOUND BIOTIN | | Descriptor: | BIOTIN, BIRA BIFUNCTIONAL PROTEIN | | Authors: | Kwon, K, Streaker, E.D, Ruparelia, S, Beckett, D. | | Deposit date: | 2001-01-12 | | Release date: | 2001-05-30 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Corepressor-induced organization and assembly of the biotin repressor: a model for allosteric activation of a transcriptional regulator.
Proc.Natl.Acad.Sci.USA, 98, 2001
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6CRO
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