4HBA
 
 | | Structural and Catalytic Characterization of a Thermal and Acid Stable Variant of Human Carbonic Anhydrase II Containing an Engineered Disulfide Bond | | 分子名称: | Carbonic anhydrase 2, GLYCEROL, ZINC ION | | 著者 | Boone, C.D, Habibzadegan, A, McKenna, R. | | 登録日 | 2012-09-27 | | 公開日 | 2013-07-31 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.762 Å) | | 主引用文献 | Structural and catalytic characterization of a thermally stable and acid-stable variant of human carbonic anhydrase II containing an engineered disulfide bond.
Acta Crystallogr.,Sect.D, 69, 2013
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6E0U
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4L5W
 | | Structural implications of the secondary CO2 binding pocket in human carbonic anhydrase II | | 分子名称: | Carbonic anhydrase 2, GLYCEROL, ZINC ION | | 著者 | Boone, C.D, Gill, S, McKenna, R. | | 登録日 | 2013-06-11 | | 公開日 | 2014-04-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural, catalytic and stabilizing consequences of aromatic cluster variants in human carbonic anhydrase II.
Arch.Biochem.Biophys., 539, 2013
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4L5U
 | | The structural implications of the secondary CO2 binding pocket in human carbonic anhydrase II | | 分子名称: | Carbonic anhydrase 2, GLYCEROL, ZINC ION | | 著者 | Boone, C.D, Gill, S, McKenna, R. | | 登録日 | 2013-06-11 | | 公開日 | 2014-04-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural, catalytic and stabilizing consequences of aromatic cluster variants in human carbonic anhydrase II.
Arch.Biochem.Biophys., 539, 2013
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4L5V
 | | The structural implications of the secondary CO2 binding pocket in human carbonic anhydrase II | | 分子名称: | Carbonic anhydrase 2, GLYCEROL, ZINC ION | | 著者 | Boone, C.D, Gill, S, McKenna, R. | | 登録日 | 2013-06-11 | | 公開日 | 2014-04-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Structural, catalytic and stabilizing consequences of aromatic cluster variants in human carbonic anhydrase II.
Arch.Biochem.Biophys., 539, 2013
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4N16
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4PXX
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4QK2
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4QK1
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4QK3
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6B21
 | | Crystal structure of AmtB from E. coli bound to TopFluor cardiolipin | | 分子名称: | Ammonia channel, [(2R,5R,11R,14S,24E)-14-[(acetyloxy)methyl]-8-{[5-(3,5-dimethyl-1H-pyrrol-2-yl-kappaN)-5-(3,5-dimethyl-2H-pyrrol-2-ylidene-kappaN)pentanoyl]oxy}-5,11-dihydroxy-2-{[(9E)-octadec-9-enoyl]oxy}-5,11,16-trioxo-4,6,10,12,15-pentaoxa-5lambda~5~,11lambda~5~-diphosphatritriacont-24-en-1-yl (9E)-octadec-9-enoatato](difluoro)boron | | 著者 | Boone, C.D, Laganowsky, A. | | 登録日 | 2017-09-19 | | 公開日 | 2018-03-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Allostery revealed within lipid binding events to membrane proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3V3J
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3V3G
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3V3I
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3V3F
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3V3H
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4M2U
 | | Carbonic Anhydrase II in complex with Dorzolamide | | 分子名称: | (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, Carbonic anhydrase 2, ZINC ION | | 著者 | Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, Mckenna, R. | | 登録日 | 2013-08-05 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
Bioorg.Med.Chem., 21, 2013
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4M2V
 | | Genetically engineered Carbonic Anhydrase IX in complex with Brinzolamide | | 分子名称: | (+)-4-ETHYLAMINO-3,4-DIHYDRO-2-(METHOXY)PROPYL-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, Carbonic anhydrase 2, ZINC ION | | 著者 | Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, Mckenna, R. | | 登録日 | 2013-08-05 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.718 Å) | | 主引用文献 | Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
Bioorg.Med.Chem., 21, 2013
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4M2R
 | | Human Carbonic Anhydrase II in complex with Brinzolamide | | 分子名称: | (+)-4-ETHYLAMINO-3,4-DIHYDRO-2-(METHOXY)PROPYL-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, Carbonic anhydrase 2, ZINC ION | | 著者 | Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, Mckenna, R. | | 登録日 | 2013-08-05 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.993 Å) | | 主引用文献 | Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
Bioorg.Med.Chem., 21, 2013
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4M2W
 | | Genetically engineered Carbonic Anhydrase IX in complex with Dorzolamide | | 分子名称: | (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, Carbonic anhydrase 2, ZINC ION | | 著者 | Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, McKenna, R. | | 登録日 | 2013-08-05 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.658 Å) | | 主引用文献 | Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
Bioorg.Med.Chem., 21, 2013
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4XZ5
 | | Structure of the thermostable alpha-Carbonic Anydrase from Thiomicrospira crunogena XCL-2 gammaproteobacterium | | 分子名称: | BICARBONATE ION, Carbonic anhydrase, alpha family, ... | | 著者 | Mahon, B.P, Diaz-Torres, N.A, Pinard, M.A, McKenna, R. | | 登録日 | 2015-02-03 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | | 主引用文献 | Structural and biophysical characterization of the alpha-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2: insights into engineering thermostable enzymes for CO2 sequestration.
Acta Crystallogr.,Sect.D, 71, 2015
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4RXY
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