4W8W
| |
4W8Z
| |
4W8V
| |
8RXB
| |
4W8X
| Crystal Structure of Cmr1 from Pyrococcus furiosus bound to a nucleotide | 分子名称: | CRISPR system Cmr subunit Cmr1-1, GUANOSINE-3'-MONOPHOSPHATE, PHOSPHATE ION | 著者 | Benda, C, Ebert, J, Baumgaertner, M, Conti, E. | 登録日 | 2014-08-26 | 公開日 | 2014-10-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4. Mol.Cell, 56, 2014
|
|
4W8Y
| Structure of full length Cmr2 from Pyrococcus furiosus (Manganese bound form) | 分子名称: | CRISPR system Cmr subunit Cmr2, MANGANESE (II) ION, ZINC ION | 著者 | Benda, C, Ebert, J, Baumgaertner, M, Conti, E. | 登録日 | 2014-08-26 | 公開日 | 2014-10-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4. Mol.Cell, 56, 2014
|
|
5AOR
| Structure of MLE RNA ADP AlF4 complex | 分子名称: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, DOSAGE COMPENSATION REGULATOR, ... | 著者 | Prabu, J.R, Conti, E. | 登録日 | 2015-09-11 | 公開日 | 2015-11-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structure of the RNA Helicase Mle Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling. Mol.Cell, 60, 2015
|
|
6Z3R
| Structure of SMG1-8-9 kinase complex bound to UPF1-LSQ | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Langer, L.M, Gat, Y, Conti, E. | 登録日 | 2020-05-21 | 公開日 | 2020-06-24 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. Elife, 9, 2020
|
|
5OKZ
| Crystal Strucrure of the Mpp6 Exosome complex | 分子名称: | CHLORIDE ION, Exosome complex component CSL4, Exosome complex component MTR3, ... | 著者 | Falk, S, Ebert, J, Conti, E. | 登録日 | 2017-07-26 | 公開日 | 2017-08-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.200039 Å) | 主引用文献 | Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase. Cell Rep, 20, 2017
|
|
7QDS
| Apo human SKI complex in the open state | 分子名称: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | 著者 | Koegel, A, Keidel, A, Bonneau, A, Schaefer, I.B, Conti, E. | 登録日 | 2021-11-30 | 公開日 | 2022-02-02 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
|
|
4Q8H
| |
4Q8G
| |
4CT6
| CNOT9-CNOT1 complex | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG | 著者 | Basquin, J, Ozgur, S, Conti, E. | 登録日 | 2014-03-12 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression. Mol.Cell, 54, 2014
|
|
4CT4
| CNOT1 MIF4G domain - DDX6 complex | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Ozgur, S, Basquin, J, Conti, E. | 登録日 | 2014-03-12 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Biochemical Insights to the Role of the Ccr4- not Complex and Ddx6 ATPase in Microrna Repression. Mol.Cell, 54, 2014
|
|
4CT7
| CNOT9-CNOT1 complex with bound tryptophan | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, ... | 著者 | Basquin, J, Ozgur, S, Conti, E. | 登録日 | 2014-03-12 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | 主引用文献 | Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression. Mol.Cell, 54, 2014
|
|
4CT5
| DDX6 | 分子名称: | ACETATE ION, DDX6 | 著者 | Ozgur, S, Basquin, J, Conti, E. | 登録日 | 2014-03-12 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression. Mol.Cell, 54, 2014
|
|
4CV5
| yeast NOT1 CN9BD-CAF40 complex | 分子名称: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, HEXATANTALUM DODECABROMIDE, PROTEIN CAF40 | 著者 | Basquin, J, Conti, E. | 登録日 | 2014-03-23 | 公開日 | 2014-05-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.807 Å) | 主引用文献 | Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression. Mol.Cell, 54, 2014
|
|
5MZN
| Helicase Sen1 | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Leonaite, B, Basquin, J, Conti, E. | 登録日 | 2017-02-01 | 公開日 | 2017-04-19 | 最終更新日 | 2017-06-14 | 実験手法 | X-RAY DIFFRACTION (1.787 Å) | 主引用文献 | Sen1 has unique structural features grafted on the architecture of the Upf1-like helicase family. EMBO J., 36, 2017
|
|
7PW4
| Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
|
|
7PW8
| Human SMG1-8-9 kinase complex bound to AMPPNP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
|
|
7PW6
| Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor - SMG1 body | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, INOSITOL HEXAKISPHOSPHATE, Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1 | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
|
|
7PW9
| Human SMG1-9 kinase complex bound to AMPPNP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
|
|
7PW7
| Human SMG1-9 kinase complex bound to a SMG1 inhibitor | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
|
|
7PW5
| |
2E2X
| |