1ZTZ
| Crystal structure of HIV protease- metallacarborane complex | 分子名称: | COBALT BIS(1,2-DICARBOLLIDE), PROTEASE RETROPEPSIN, autoproteolytic tetrapeptide | 著者 | Cigler, P, Kozisek, M, Rezacova, P, Brynda, J, Otwinowski, Z, Sedlacek, J, Bodem, J, Kraeusslich, H.-G, Kral, V, Konvalinka, J. | 登録日 | 2005-05-28 | 公開日 | 2005-11-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | From nonpeptide toward noncarbon protease inhibitors: Metallacarboranes as specific and potent inhibitors of HIV protease Proc.Natl.Acad.Sci.USA, 102, 2005
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3T3C
| Structure of HIV PR resistant patient derived mutant (comprising 22 mutations) in complex with DRV | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, BETA-MERCAPTOETHANOL, HIV-1 protease, ... | 著者 | Rezacova, P, Kozisek, M, Konvalinka, J, Saskova, K.G. | 登録日 | 2011-07-25 | 公開日 | 2012-06-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease. Antimicrob.Agents Chemother., 56, 2012
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2BUO
| HIV-1 capsid C-terminal domain in complex with an inhibitor of particle assembly | 分子名称: | ACETIC ACID, HIV-1 CAPSID PROTEIN, INHIBITOR OF CAPSID ASSEMBLY | 著者 | Ternois, F, Sticht, J, Duquerroy, S, Krausslich, H.-G, Rey, F.A. | 登録日 | 2005-06-17 | 公開日 | 2005-07-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The HIV-1 Capsid Protein C-Terminal Domain in Complex with a Virus Assembly Inhibitor Nat.Struct.Mol.Biol., 12, 2005
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