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Structure of plasmepsin II in complex with 2-aminoquinazolin-4(3H)-one based open-flap inhibitor
Descriptor:	2-azanyl-3-[[(2~{R})-oxolan-2-yl]methyl]-7-(5-phenylpentyl)quinazolin-4-one, Plasmepsin II
Authors:	Bobrovs, R, Jaudzems, K.
Deposit date:	2022-01-28
Release date:	2022-06-29
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (3.33 Å)
Cite:	Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials. J.Chem.Inf.Model., 62, 2022

Structure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors
Descriptor:	2-oxidanyl-5-[[4-(phenylmethyl)phenyl]sulfamoyl]benzoic acid, GLYCEROL, Threonine--tRNA ligase, ...
Authors:	Rodriguez, J.A, Parisini, E.
Deposit date:	2023-09-13
Release date:	2024-04-10
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Structure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors. Plos One, 19, 2024

NMR structure of BB_A03, Borrelia burgdorferi outer surface lipoprotein
Descriptor:	Putative outer membrane protein BBA03
Authors:	Fridmanis, J, Brangulis, K, Jaudzems, K.
Deposit date:	2019-02-20
Release date:	2020-03-18
Last modified:	2024-06-19
Method:	SOLUTION NMR
Cite:	Structural and Functional Analysis of BBA03, Borrelia burgdorferi Competitive Advantage Promoting Outer Surface Lipoprotein. Pathogens, 9, 2020

Solution structure of sortase A from S. aureus in complex with 2-(aminomethyl)-3-hydroxy-4H-pyran-4-one based prodrug
Descriptor:	6-(hydroxymethyl)-3-oxidanyl-2-(thiophen-3-ylmethyl)pyran-4-one, Sortase A
Authors:	Jaudzems, K, Leonchiks, A.
Deposit date:	2019-03-15
Release date:	2020-01-22
Last modified:	2023-06-14
Method:	SOLUTION NMR
Cite:	Targeting Bacterial Sortase A with Covalent Inhibitors: 27 New Starting Points for Structure-Based Hit-to-Lead Optimization. Acs Infect Dis., 6, 2020