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Aurora A kinase bound to a highly selective imidazopyridine inhibitor
Descriptor:	(S)-N-(1-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)pyrrolidin-3-yl)acetamide, AURORA KINASE A
Authors:	Joshi, A, Kosmopoulou, M, Bayliss, R.
Deposit date:	2013-07-19
Release date:	2013-11-20
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.75 Å)
Cite:	Aurora Isoform Selectivity: Design and Synthesis of Imidazo[4,5-B]Pyridine Derivatives as Highly Selective Inhibitors of Aurora-A Kinase in Cells. J.Med.Chem., 56, 2013

Aurora A kinase bound to a highly selective imidazopyridine inhibitor
Descriptor:	(S)-N-((1-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)pyrrolidin-3-yl)methyl)acetamide, AURORA KINASE A
Authors:	Joshi, A, Kosmopoulou, M, Bayliss, R.
Deposit date:	2013-07-19
Release date:	2013-11-20
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Aurora Isoform Selectivity: Design and Synthesis of Imidazo[4,5-B]Pyridine Derivatives as Highly Selective Inhibitors of Aurora-A Kinase in Cells. J.Med.Chem., 56, 2013

CDK8-CYCC IN COMPLEX WITH [6-Hydroxy-3-(3-methyl-benzyl)-1H-indazol-5-yl]-((S)-3-hydroxy-pyrrolidin-1-yl)-methanone
Descriptor:	1,2-ETHANEDIOL, Cyclin-C, Cyclin-dependent kinase 8, ...
Authors:	Musil, D, Blagg, J, Schiemann, K.
Deposit date:	2016-01-18
Release date:	2016-04-27
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (2.35 Å)
Cite:	CDK8-CYCC IN COMPLEX WITH [6-Hydroxy-3-(3-methyl-benzyl)-1H-indazol-5-yl]-((S)-3-hydroxy-pyrrolidin-1-yl)-methanone To Be Published