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3NGH
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BU of 3ngh by Molmil
Molecular Analysis of the Interaction of the HDL Receptor SR-BI with the Adaptor Protein PDZK1
分子名称: PDZ domain-containing protein 1
著者Kocher, O, Birrane, G, Krieger, M, Ladias, J.A.
登録日2010-06-11
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献In vitro and in vivo analysis of the binding of the C terminus of the HDL receptor scavenger receptor class B, type I (SR-BI), to the PDZ1 domain of its adaptor protein PDZK1.
J.Biol.Chem., 285, 2010
1G9O
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BU of 1g9o by Molmil
FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR
分子名称: NHE-RF
著者Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A.
登録日2000-11-26
公開日2001-05-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains.
J.Mol.Biol., 308, 2001
6WT3
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BU of 6wt3 by Molmil
Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase
分子名称: 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN
著者Luz, J.G, Birrane, G, Young, S.G, Meiyappan, M, Ploug, M.
登録日2020-05-01
公開日2020-07-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase.
J.Lipid Res., 61, 2020
6WN4
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BU of 6wn4 by Molmil
Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase
分子名称: 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN, Lipoprotein lipase peptide
著者Luz, J.G, Birrane, G, Young, S.G, Meiyappan, M, Ploug, M.
登録日2020-04-22
公開日2020-07-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase.
J.Lipid Res., 61, 2020
3R68
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BU of 3r68 by Molmil
Molecular Analysis of the PDZ3 domain of PDZK1
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Kocher, O, Birrane, G, Krieger, M.
登録日2011-03-21
公開日2011-05-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I.
J.Biol.Chem., 286, 2011
3R69
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BU of 3r69 by Molmil
Molecular analysis of the interaction of the HDL-receptor SR-BI with the PDZ3 domain of its adaptor protein PDZK1
分子名称: CITRIC ACID, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Scavenger receptor class B member 1
著者Kocher, O, Birrane, G, Krieger, M.
登録日2011-03-21
公開日2011-05-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I.
J.Biol.Chem., 286, 2011
2HO2
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BU of 2ho2 by Molmil
Structure of human FE65-WW domain in complex with hMena peptide.
分子名称: Amyloid beta A4 protein-binding family B member 1, GLYCEROL, Protein enabled homolog
著者Meiyappan, M, Birrane, G, Ladias, J.A.
登録日2006-07-13
公開日2007-07-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Structural Basis for Polyproline Recognition by the FE65 WW Domain.
J.Mol.Biol., 372, 2007
2I53
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BU of 2i53 by Molmil
Crystal structure of Cyclin K
分子名称: ACETATE ION, Cyclin K
著者Baek, K, Brown, R.S, Birrane, G, Ladias, J.A.A.
登録日2006-08-23
公開日2007-01-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Human Cyclin K, a Positive Regulator of Cyclin-dependent Kinase 9.
J.Mol.Biol., 366, 2007
2IDH
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BU of 2idh by Molmil
Crystal Structure of human FE65 WW domain
分子名称: Amyloid beta A4 protein-binding family B member 1, SULFATE ION, TETRAETHYLENE GLYCOL
著者Meiyappan, M, Birrane, G, Ladias, J.A.A.
登録日2006-09-15
公開日2007-07-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural Basis for Polyproline Recognition by the FE65 WW Domain.
J.Mol.Biol., 372, 2007
2KG2
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BU of 2kg2 by Molmil
Solution structure of a PDZ protein
分子名称: Tax1-binding protein 3
著者Durney, M.A, Birrane, G, Anklin, C, Soni, A, Ladias, J.A.A.
登録日2009-03-02
公開日2010-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the human Tax-interacting protein-1.
J.Biomol.Nmr, 45, 2009
2OEI
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BU of 2oei by Molmil
Crystal structure of human FE65-WW domain in complex with human Mena peptide
分子名称: Amyloid beta A4 protein-binding family B member 1, poly-proline peptide
著者Meiyappan, M, Birrane, G, Ladias, J.A.A.
登録日2006-12-29
公開日2007-07-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural Basis for Polyproline Recognition by the FE65 WW Domain.
J.Mol.Biol., 372, 2007
5C0N
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BU of 5c0n by Molmil
Development of a monoclonal antibody targeting secreted aP2 to treat diabetes and fatty liver disease
分子名称: Fab CA33 Heavy chain, Fab CA33 light chain, Fatty acid-binding protein, ...
著者Doyle, C.
登録日2015-06-12
公開日2015-06-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015
6NJ8
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BU of 6nj8 by Molmil
Encapsulin iron storage compartment from Quasibacillus thermotolerans
分子名称: Encapsulating protein for a DyP-type peroxidase, targeting peptide
著者Orlando, B.J, Giessen, T.W, Chambers, M.G, Liao, M, Silver, P.A.
登録日2019-01-02
公開日2019-08-07
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Large protein organelles form a new iron sequestration system with high storage capacity.
Elife, 8, 2019
5UEG
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BU of 5ueg by Molmil
RNA primer-template complex with guanosine dinucleotide G(5')pppp(5')G ligand
分子名称: RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl] hydrogen phosphate
著者Zhang, W, Tam, C.P, Szostak, J.W.
登録日2017-01-02
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UEF
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BU of 5uef by Molmil
RNA primer-template complex with guanosine dinucleotide p(5')G(3')p(5')G ligand
分子名称: RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), RNA (5'-R(P*GP*G)-3')
著者Zhang, W, Tam, C.P, Szostak, J.W.
登録日2017-01-02
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UED
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BU of 5ued by Molmil
RNA primer-template complex with guanosine dinucleotide ligand G(5')pp(5')G
分子名称: RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate
著者Zhang, W, Tam, C.P, Szostak, J.W.
登録日2017-01-01
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UEE
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BU of 5uee by Molmil
RNA primer-template complex with guanosine dinucleotide ligand G(5')ppp(5')G
分子名称: DIGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3')
著者Zhang, W, Tam, C.P, Szostak, J.W.
登録日2017-01-01
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1GQ4
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BU of 1gq4 by Molmil
STRUCTURAL DETERMINANTS OF THE NHERF INTERACTION WITH BETA2AR AND PDGFR
分子名称: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50
著者Karthikeyan, S, Leung, T, Ladias, J.A.A.
登録日2001-11-19
公開日2002-05-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors
J.Biol.Chem., 277, 2002
1GQ5
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BU of 1gq5 by Molmil
Structural Determinants of the NHERF Interaction with beta2-AR and PDGFR
分子名称: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50
著者Karthikeyan, S, Leung, T, Ladias, J.A.A.
登録日2001-11-20
公開日2002-11-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors
J.Biol.Chem., 277, 2002
1I92
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STRUCTURAL BASIS OF THE NHERF PDZ1-CFTR INTERACTION
分子名称: CHLORIDE ION, NA+/H+ EXCHANGE REGULATORY CO-FACTOR
著者Karthikeyan, S, Leung, T, Ladias, J.A.A.
登録日2001-03-16
公開日2001-06-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator.
J.Biol.Chem., 276, 2001
5HUZ
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BU of 5huz by Molmil
Solution structure of coiled coil domain of myosin binding subunit of myosin light chain phosphatase
分子名称: Protein phosphatase 1 regulatory subunit 12A
著者Sharma, A.K, Birrane, G, Anklin, C, Rigby, A.C, Pollak, M, Alper, S.L.
登録日2016-01-27
公開日2016-03-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献To be published
To Be Published
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219869

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