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4R2Z
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BU of 4r2z by Molmil
Molecular Analysis of the PDZ4 Domain of Mouse PDZK1
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3
著者Birrane, G, Kocher, O, Krieger, M.
登録日2014-08-13
公開日2015-08-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular Analysis of the PDZ4 domain from Mouse PDZK1
To be Published
4XWH
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BU of 4xwh by Molmil
Crystal structure of the human N-acetyl-alpha-glucosaminidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-N-acetylglucosaminidase, ...
著者Birrane, G, Meiyappan, M, Dassier, A.
登録日2015-01-28
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural characterization of the alpha-N-acetylglucosaminidase, a key enzyme in the pathogenesis of Sanfilippo syndrome B.
J.Struct.Biol., 205, 2019
4LG0
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BU of 4lg0 by Molmil
Structure of a ternary FOXO1-ETS1 DNA complex
分子名称: CALCIUM ION, DNA (5'-D(*DAP*DAP*DAP*DCP*DAP*DAP*DTP*DAP*DAP*DCP*DAP*DGP*DGP*DAP*DAP*DAP*DCP*DCP*DGP*DTP*DG)-3'), DNA (5'-D(*DTP*DTP*DCP*DAP*DCP*DGP*DGP*DTP*DTP*DTP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DTP*DTP*DGP*DT)-3'), ...
著者Birrane, G, Choy, W.C, Datta, D, Geiger, C.A, Grant, M.A.
登録日2013-06-27
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structure of a ternary FOXO1-ETS1 DNA complex
To be Published
6E7K
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BU of 6e7k by Molmil
Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride hydrolysis
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Birrane, G, Meiyappan, M.
登録日2018-07-26
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
3BYA
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BU of 3bya by Molmil
Structure of a Calmodulin Complex
分子名称: CALCIUM ION, Calmodulin, Glutamate [NMDA] receptor subunit zeta-1 peptide
著者Birrane, G, Soni, A, Ladias, J.A.A.
登録日2008-01-15
公開日2009-01-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of a Calmodulin Complex
To be Published
3CMY
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BU of 3cmy by Molmil
Structure of a homeodomain in complex with DNA
分子名称: 1,2-ETHANEDIOL, 5'-D(*DAP*DCP*DAP*DTP*DAP*DAP*DP*DCP*DGP*DAP*DTP*DTP*DAP*DC)-3', 5'-D(*DTP*DGP*DTP*DAP*DAP*DTP*DCP*DGP*DAP*DTP*DTP*DAP*DTP*DG)-3', ...
著者Birrane, G, Ladias, J.A.A, Soni, A.
登録日2008-03-24
公開日2009-02-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Basis for DNA Recognition by the Human PAX3 Homeodomain.
Biochemistry, 48, 2009
2NTE
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BU of 2nte by Molmil
Crystal Structure of the BARD1 BRCT Domains
分子名称: 1,2-ETHANEDIOL, BRCA1-associated RING domain protein 1, CHLORIDE ION, ...
著者Birrane, G, Varma, A.K, Soni, A, Ladias, J.A.A.
登録日2006-11-07
公開日2007-06-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the BARD1 BRCT domains.
Biochemistry, 46, 2007
1MFG
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BU of 1mfg by Molmil
The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor
分子名称: Erb-B2 INTERACTING PROTEIN, Erb-B2 carboxyl-terminal fragment
著者Birrane, G, Chung, J, Ladias, J.A.
登録日2002-08-10
公開日2003-01-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Novel mode of ligand recognition by the erbin PDZ domain
J.Biol.Chem., 278, 2003
1MFL
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BU of 1mfl by Molmil
The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor
分子名称: Erb-B2 INTERACTING PROTEIN, PHOSPHORYLATED Erb-B2 carboxyl-terminal fragment.
著者Birrane, G, Chung, J, Ladias, J.A.
登録日2002-08-12
公開日2003-01-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Novel mode of ligand recognition by the erbin PDZ domain
J.Biol.Chem., 278, 2003
3QH5
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BU of 3qh5 by Molmil
Structure of Thermolysin in complex with N-Carbobenzyloxy-L-aspartic acid and L-Phenylalanine Methyl Ester
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, N-[(benzyloxy)carbonyl]-L-aspartic acid, ...
著者Birrane, G, Bhyravbhatla, B, Navia, M.
登録日2011-01-25
公開日2012-01-04
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Synthesis of Aspartame by Thermolysin: An X-ray Structural Study.
ACS MED.CHEM.LETT., 5, 2014
3QGO
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BU of 3qgo by Molmil
Structure of Thermolysin in complex with L-Phenylalanine methylester
分子名称: ACETATE ION, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者Birrane, G, Bhyravbhatla, B, Navia, M.
登録日2011-01-24
公開日2012-01-04
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Synthesis of Aspartame by Thermolysin: An X-ray Structural Study.
ACS MED.CHEM.LETT., 5, 2014
3QH1
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BU of 3qh1 by Molmil
Structure of Thermolysin in complex with N-benzyloxycarbonyl-L-aspartic acid
分子名称: CALCIUM ION, N-[(benzyloxy)carbonyl]-L-aspartic acid, Thermolysin, ...
著者Birrane, G, Bhyravbhatla, B, Navia, M.
登録日2011-01-25
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Synthesis of Aspartame by Thermolysin: An X-ray Structural Study.
ACS MED.CHEM.LETT., 5, 2014
6XIY
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BU of 6xiy by Molmil
Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to methyl 2-(acetylamino)-2-deoxy-1-thio-alpha-D-galactopyranose
分子名称: C-type lectin domain family 10 member A, CALCIUM ION, CHLORIDE ION, ...
著者Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G.
登録日2020-06-22
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.307 Å)
主引用文献Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen.
Biochemistry, 60, 2021
6N63
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BU of 6n63 by Molmil
Crystal structure of an Iron binding protein
分子名称: ACETATE ION, ENCAPSULIN CARGO PROTEIN, FE (III) ION, ...
著者Birrane, G, Geissen, T.W.
登録日2018-11-24
公開日2019-07-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Large protein organelles form a new iron sequestration system with high storage capacity.
Elife, 8, 2019
4F8K
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BU of 4f8k by Molmil
Molecular analysis of the interaction between the prostacyclin receptor and the first PDZ domain of PDZK1
分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Prostacyclin receptor
著者Kocher, O, Birrane, G, Kinsella, B.T, Mulvaney, E.P.
登録日2012-05-17
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular Analysis of the Prostacyclin Receptor's Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1.
Plos One, 8, 2013
6W12
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BU of 6w12 by Molmil
Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to the Tumor-Associated Tn Antigen
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, C-type lectin domain family 10 member A, CALCIUM ION, ...
著者Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G.
登録日2020-03-03
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen.
Biochemistry, 60, 2021
6O31
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BU of 6o31 by Molmil
CRYSTAL STRUCTURE OF THE ACTIN-BINDING DOMAIN OF HUMAN ALPHA-ACTININ-4
分子名称: Alpha-actinin-4
著者Birrane, G, Feng, D.
登録日2019-02-25
公開日2020-02-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis.
J. Am. Soc. Nephrol., 31, 2020
6OA6
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BU of 6oa6 by Molmil
CRYSTAL STRUCTURE OF THE ACTIN-BINDING DOMAIN OF HUMAN ALPHA-ACTININ-4
分子名称: Alpha-actinin-4, GLYCEROL
著者Birrane, G, Feng, D.
登録日2019-03-15
公開日2020-03-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis.
J. Am. Soc. Nephrol., 31, 2020
6PY1
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BU of 6py1 by Molmil
Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, ACETATE ION, C-type lectin domain family 10 member A, ...
著者Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G.
登録日2019-07-28
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen.
Biochemistry, 60, 2021
6PUV
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BU of 6puv by Molmil
Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin
分子名称: C-type lectin domain family 10 member A, CALCIUM ION
著者Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G.
登録日2019-07-18
公開日2020-07-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen.
Biochemistry, 60, 2021
2ING
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BU of 2ing by Molmil
X-ray Structure of the BRCA1 BRCT mutant M1775K
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
著者Birrane, G, Soni, A, Ladias, J.A.A.
登録日2006-10-07
公開日2007-09-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
Eur.J.Hum.Genet., 16, 2008
1Q9H
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BU of 1q9h by Molmil
3-Dimensional structure of native Cel7A from Talaromyces emersonii
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, cellobiohydrolase I catalytic domain
著者Grassick, A, Thompson, R, Murray, P.G, Collins, C.M, Byrnes, L, Tuohy, M.G, Birrane, G, Higgins, T.M.
登録日2003-08-25
公開日2004-11-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Three-dimensional structure of a thermostable native cellobiohydrolase, CBH IB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii
Eur.J.Biochem., 271, 2004
5D8J
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BU of 5d8j by Molmil
Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes.
分子名称: Fatty acid-binding protein, adipocyte, HA3 Fab Heavy Chain, ...
著者Doyle, C, Birrane, G.
登録日2015-08-17
公開日2016-01-13
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015
1G9O
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BU of 1g9o by Molmil
FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR
分子名称: NHE-RF
著者Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A.
登録日2000-11-26
公開日2001-05-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains.
J.Mol.Biol., 308, 2001
1Y98
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BU of 1y98 by Molmil
Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, CtIP PHOSPHORYLATED PEPTIDE, ...
著者Varma, A.K, Brown, R.S, Birrane, G, Ladias, J.A.A.
登録日2004-12-14
公開日2005-08-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex.
Biochemistry, 44, 2005

 

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