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Novel kinase profile highlights the temporal basis of context dependent checkpoint pathways to cell death
Descriptor:	3-methyl-5-[5-(1-methylethyl)-1H-benzimidazol-2-yl]-N-(1-methylpiperidin-4-yl)-1H-pyrazole-4-carboxamide, Serine/threonine-protein kinase Chk1
Authors:	Massey, A.J, Borgognoni, J, Bentley, C, Foloppe, N, Fiumana, A, Walmsley, L.
Deposit date:	2010-06-21
Release date:	2011-05-18
Last modified:	2024-03-20
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Context-dependent cell cycle checkpoint abrogation by a novel kinase inhibitor Plos One, 5, 2010

Crystal structure of a polysaccharide-binding human Fab (F598)
Descriptor:	Fab (F598) Heavy Chain, Fab (F598) Light Chain
Authors:	Soliman, C, Ramsland, P.A.
Deposit date:	2017-10-24
Release date:	2018-02-21
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine. J. Biol. Chem., 293, 2018

Crystal structure of a polysaccharide-binding human Fab (F598) in complex with N-acetyl-D-glucosamine (GlcNAc)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Fab (F598) Heavy Chain, Fab (F598) Light Chain
Authors:	Soliman, C, Ramsland, P.A.
Deposit date:	2017-10-24
Release date:	2018-02-21
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine. J. Biol. Chem., 293, 2018

Crystal structure of a polysaccharide-binding human Fab (F598) in complex with nona-N-acetyl-D-glucosamine (9NAc)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab (F598) Heavy Chain, Fab(F598) Light Chain
Authors:	Soliman, C, Ramsland, P.A.
Deposit date:	2017-10-24
Release date:	2018-02-21
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine. J. Biol. Chem., 293, 2018