4POF
 
 | | PfMCM N-terminal domain without DNA | | Descriptor: | Cell division control protein 21, ZINC ION | | Authors: | Froelich, C.A, Kang, S, Epling, L.B, Bell, S.P, Enemark, E.J. | | Deposit date: | 2014-02-25 | | Release date: | 2014-04-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.648 Å) | | Cite: | A conserved MCM single-stranded DNA binding element is essential for replication initiation.
Elife, 3, 2014
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4POG
 | | MCM-ssDNA co-crystal structure | | Descriptor: | 30-mer oligo(dT), Cell division control protein 21, ZINC ION | | Authors: | Froelich, C.A, Kang, S, Epling, L.B, Bell, S.P, Enemark, E.J. | | Deposit date: | 2014-02-25 | | Release date: | 2014-04-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.203 Å) | | Cite: | A conserved MCM single-stranded DNA binding element is essential for replication initiation.
Elife, 3, 2014
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7O18
 | | N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH I-BET282 | | Descriptor: | (R)-4-(8-methoxy-1-(1-methoxypropan-2-yl)-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinolin-7-yl)-3,5-dimethylisoxazole, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | | Authors: | Chung, C. | | Deposit date: | 2021-03-28 | | Release date: | 2021-10-13 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Discovery of a Novel Bromodomain and Extra Terminal Domain (BET) Protein Inhibitor, I-BET282E, Suitable for Clinical Progression.
J.Med.Chem., 64, 2021
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