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1E5U
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BU of 1e5u by Molmil
NMR Representative Structure of Intimin-190 (Int190) from Enteropathogenic E. coli
Descriptor: INTIMIN
Authors:Prasannan, S, Matthews, S.J, Batchelor, M, Daniell, S, Reece, S, Frankel, G, Dougan, G, Connerton, I, Bloomberg, G.
Deposit date:2000-08-02
Release date:2000-08-16
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Structural Basis for Recognition of the Translocated Intimin Receptor (Tir) by Intimin from Enteropathogenic E. Coli
Embo J., 19, 2000
2W9D
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BU of 2w9d by Molmil
Structure of Fab fragment of the ICSM 18 - anti-Prp therapeutic antibody at 1.57 A resolution.
Descriptor: CALCIUM ION, ICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN, ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN
Authors:Antonyuk, S.V, Trevitt, C.R, Strange, R.W, Jackson, G.S, Sangar, D, Batchelor, M, Jones, S, Georgiou, T, Cooper, S, Fraser, C, Khalili-Shirazi, A, Clarke, A.R, Hasnain, S.S, Collinge, J.
Deposit date:2009-01-23
Release date:2009-02-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Crystal Structure of Human Prion Protein Bound to a Therapeutic Antibody.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WD1
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BU of 2wd1 by Molmil
Human c-Met Kinase in complex with azaindole inhibitor
Descriptor: 1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE, GAMMA-BUTYROLACTONE, HEPATOCYTE GROWTH FACTOR RECEPTOR
Authors:Porter, J, Lumb, S, Franklin, R.J, Gascon-Simorte, J.M, Calmiano, M, Le Riche, K, Lallemand, B, Keyaerts, J, Edwards, H, Maloney, A, Delgado, J, King, L, Foley, A, Lecomte, F, Reuberson, J, Meier, C, Batchelor, M.
Deposit date:2009-03-19
Release date:2009-04-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of 4-Azaindoles as Novel Inhibitors of C- met Kinase.
Bioorg.Med.Chem.Lett., 19, 2009
2W9E
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BU of 2w9e by Molmil
Structure of ICSM 18 (anti-Prp therapeutic antibody) Fab fragment complexed with human Prp fragment 119-231
Descriptor: ICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN, ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN, MAJOR PRION PROTEIN, ...
Authors:Antonyuk, S.V, Trevitt, C.R, Strange, R.W, Jackson, G.S, Sangar, D, Batchelor, M, Jones, S, Georgiou, T, Cooper, S, Fraser, C, Khalili-Shirazi, A, Clarke, A.R, Hasnain, S.S, Collinge, J.
Deposit date:2009-01-23
Release date:2009-02-03
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of Human Prion Protein Bound to a Therapeutic Antibody.
Proc.Natl.Acad.Sci.USA, 106, 2009
3F66
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BU of 3f66 by Molmil
Human c-Met Kinase in complex with quinoxaline inhibitor
Descriptor: 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol, GAMMA-BUTYROLACTONE, Hepatocyte growth factor receptor, ...
Authors:Meier, C, Ceska, T.
Deposit date:2008-11-05
Release date:2008-12-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase.
Bioorg.Med.Chem.Lett., 19, 2009
6SV2
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BU of 6sv2 by Molmil
Human prion protein (PrP) fragment 119-231 (G127V M129 variant) complexed to ICSM 18 (anti-Prp therapeutic antibody) Fab fragment
Descriptor: ICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN, ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN, Major prion protein, ...
Authors:Conners, R.
Deposit date:2019-09-17
Release date:2020-07-29
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural effects of the highly protective V127 polymorphism on human prion protein.
Commun Biol, 3, 2020
6SUZ
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BU of 6suz by Molmil
Human prion protein (PrP) fragment 119-231 (G127V V129 variant) complexed to ICSM 18 (anti-Prp therapeutic antibody) Fab fragment
Descriptor: ICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN, ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN, Major prion protein, ...
Authors:Conners, R.
Deposit date:2019-09-17
Release date:2020-08-12
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural effects of the highly protective V127 polymorphism on human prion protein.
Commun Biol, 3, 2020
8PR7
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BU of 8pr7 by Molmil
Aurora-A in complex with CEP192 and an inhibitory monobody
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, Centrosomal protein of 192 kDa, ...
Authors:Miles, J.A, Bayliss, R.
Deposit date:2023-07-12
Release date:2024-07-24
Last modified:2025-02-05
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2.
Embo J., 43, 2024

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