Search by PDB author

Crystal Structure of Benzamide Tetrahydro-4H-carbazol-4-one bound to Hsp90
分子名称:	2-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamide, Heat shock protein HSP 90-alpha
著者	Barta, T.E, Veal, J.M, Huang, K.H, Hall, S.H.
登録日	2008-05-01
公開日	2008-06-17
最終更新日	2024-04-10
実験手法	X-RAY DIFFRACTION (1.74 Å)
主引用文献	Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90 BIOORG.MED.CHEM.LETT., 18, 2008

MMP-13 in complex with selective tetrazole core inhibitor
分子名称:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, Collagenase 3, ...
著者	Kiefer, J.R, Barta, T.E, Becker, D.P, Mathis, K.J, Williams, J.
登録日	2010-07-22
公開日	2011-08-10
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	MMP-13 in complex with selective tetrazole core inhibitor To be Published

Crystal structure of MMP-13 in complex with SC-78080
分子名称:	1-(2-methoxyethyl)-N-oxo-4-({4-[4-(trifluoromethoxy)phenoxy]phenyl}sulfonyl)piperidine-4-carboxamide, CALCIUM ION, Collagenase 3, ...
著者	Kiefer, J.R, Williams, J.M, Becker, D.P.
登録日	2009-11-19
公開日	2010-10-06
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Orally-active MMP-1 sparing alpha-tetrahydropyranyl and alpha-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease J.Med.Chem., 53, 2010

Crystal Structure of Benzamide SNX-1321 bound to Hsp90
分子名称:	2-[(3,4,5-trimethoxyphenyl)amino]-4-(2,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)benzamide, Heat shock protein HSP 90-alpha
著者	Veal, J.M, Fadden, P, Huang, K.H, Rice, J, Hall, S.E, Haytstead, T.A.
登録日	2010-04-22
公開日	2010-08-11
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90. Chem.Biol., 17, 2010