5U81
 
 | | Acid ceramidase (ASAH1, aCDase) from naked mole rat, Cys143Ala, uncleaved | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid ceramidase isoform b, CHLORIDE ION, ... | | Authors: | Gebai, A, Gorelik, A, Illes, K, Nagar, B. | | Deposit date: | 2016-12-13 | | Release date: | 2018-03-28 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural basis for the activation of acid ceramidase.
Nat Commun, 9, 2018
|
|
5U85
 | | Murine saposin-D (SapD), open conformation | | Descriptor: | Saposin-D | | Authors: | Gebai, A, Gorelik, A, Illes, K, Nagar, B. | | Deposit date: | 2016-12-13 | | Release date: | 2018-06-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of saposin D in an open conformation.
J. Struct. Biol., 204, 2018
|
|
5U84
 | | Acid ceramidase (ASAH1, aCDase) from common minke whale, Cys143Ala, uncleaved | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, ... | | Authors: | Gebai, A, Gorelik, A, Illes, K, Nagar, B. | | Deposit date: | 2016-12-13 | | Release date: | 2018-03-28 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Structural basis for the activation of acid ceramidase.
Nat Commun, 9, 2018
|
|
5U7Z
 | | Human acid ceramidase (ASAH1, aCDase) self-activated | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid ceramidase, SULFATE ION, ... | | Authors: | Gebai, A, Gorelik, A, Illes, K, Nagar, B. | | Deposit date: | 2016-12-13 | | Release date: | 2018-03-28 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for the activation of acid ceramidase.
Nat Commun, 9, 2018
|
|
4L0G
 | | Crystal Structure of a GH48 cellobiohydrolase from Caldicellulosiruptor bescii | | Descriptor: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycoside hydrolase family 48, ... | | Authors: | Jiao, A, Bai, A, Yan, F, Geng, W. | | Deposit date: | 2013-05-31 | | Release date: | 2014-04-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystallization and preliminary X-ray analysis of a processive cellobiohydrolase CbCBH48A from Caldicellulosiruptor bescii
to be published
|
|
4L6X
 | |
3TTI
 | | Crystal Structure of JNK3 complexed with CC-930, an orally active anti-fibrotic JNK inhibitor | | Descriptor: | GLYCEROL, Mitogen-activated protein kinase 10, trans-4-({9-[(3S)-tetrahydrofuran-3-yl]-8-[(2,4,6-trifluorophenyl)amino]-9H-purin-2-yl}amino)cyclohexanol | | Authors: | Plantevin-Krenitsky, V, Nadolny, L, Delgado, M, Ayala, L, Clareen, S, Hilgraf, R, Albers, R, Hegde, S, D'Sidocky, N, Sapienza, J, Wright, J, McCarrick, M, Bahmanyar, S, Chamberlain, P, Delker, S.L, Muir, J, Giegel, D, Xu, L, Celeridad, M, Lachowitzer, J, Bennett, B, Moghaddam, M, Khatsenko, O, Katz, J, Fan, R, Bai, A, Tang, Y, Shirley, M.A, Benish, B, Bodine, T, Blease, K, Raymon, H, Cathers, B.E, Satoh, Y. | | Deposit date: | 2011-09-14 | | Release date: | 2012-02-01 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor.
Bioorg.Med.Chem.Lett., 22, 2012
|
|
9FV6
 | | MsbA in Amphipol A8-35 inward-facing wide open | | Descriptor: | ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FVA
 | | MsbA in MSP2N2 Nanodisc inward-facing wide open | | Descriptor: | ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FUT
 | | MsbA in GDN inward-facing narrow | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FV2
 | | MsbA in MSP1E3D1 Nanodisc inward-facing narrow open | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FV1
 | | MsbA in MSP1D1 (EPL:PC) Nanodisc inward-facing narrow open | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FV0
 | | MsbA in MSP1D1 Nanodisc inward-facing narrow open | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shearer, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FUV
 | | MsbA in Triton inward-facing wide open | | Descriptor: | ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FUS
 | | MsbA in LMNG inward-facing wide open | | Descriptor: | ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FV4
 | | MsbA in peptidisc inward-facing narrow (-) open | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FV5
 | | MsbA in peptidisc inward-facing narrow open | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FV8
 | | MsbA in Amphipol 18 inward-facing wide open | | Descriptor: | ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FUU
 | | MsbA in GDN inward-facing wide open | | Descriptor: | ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FUY
 | | MsbA in UDM inward-facing wide open | | Descriptor: | ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FV7
 | | MsbA in Amphipol A8-35 inward-facing wide (+) open | | Descriptor: | ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FUR
 | | MsbA in LMNG inward-facing narrow | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FUW
 | | MsbA in Triton inward-facing wide (+) open | | Descriptor: | ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FUZ
 | | MsbA in UDM inward-facing wide (+) open | | Descriptor: | ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
9FV3
 | | MsbA in MSP2N2 Nanodisc inward-facing narrow open | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase | | Authors: | Hoffmann, L, Baier, A, Jorde, L, Kamel, M, Schaefer, J, Schnelle, K, Scholz, A, Shvarev, D, Wong, J, Parey, K, Januliene, D, Moeller, A. | | Deposit date: | 2024-06-26 | | Release date: | 2025-03-19 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | The ABC transporter MsbA in a dozen environments.
Structure, 33, 2025
|
|
