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Crystal structure of apo-acyl carrier protein from Leishmania major
分子名称:	Acyl carrier protein
著者	Arya, R, Sharma, B, Makde, R.D, Kundu, S.
登録日	2018-05-16
公開日	2019-01-16
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	A conformational switch from a closed apo- to an open holo-form equips the acyl carrier protein for acyl chain accommodation. Biochim Biophys Acta Proteins Proteom, 1867, 2018

Crystal structure of the S37A mutant of apo-acyl carrier protein from Leishmania major
分子名称:	Acyl carrier protein
著者	Sharma, B, Arya, R, Kundu, S, Makde, R.D.
登録日	2018-05-16
公開日	2019-01-16
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	A conformational switch from a closed apo- to an open holo-form equips the acyl carrier protein for acyl chain accommodation. Biochim Biophys Acta Proteins Proteom, 1867, 2018

Human ERAP1 bound to phosphinic pseudotripeptide inhibitor DG013
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum aminopeptidase 1, Nalpha-[(2S)-2-{[[(1R)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]methyl}-4-methylpentanoyl]-L-tryptophanamide, ...
著者	Maben, Z, Stern, L.J.
登録日	2018-08-22
公開日	2019-12-18
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (3.31 Å)
主引用文献	Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism. Nat Commun, 12, 2021

ERAP1 in the open conformation bound to 10mer phosphinic inhibitor DG014
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum aminopeptidase 1, Phosphinic inhibitor DG014, ...
著者	Stern, L.J, Maben, Z.
登録日	2018-09-14
公開日	2019-12-18
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.92 Å)
主引用文献	Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism. Nat Commun, 12, 2021