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7SHI
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BU of 7shi by Molmil
Crystal Structure of Cytochrome P450 AmphL from Streptomyces nodosus and the Structural Basis for Substrate Selectivity in Macrolide Metabolizing P450s
Descriptor: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,22E,33S,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,22-diene-36-carboxylic acid, AmphL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Amaya, J.A, Poulos, T.L.
Deposit date:2021-10-08
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.00002766 Å)
Cite:Structural analysis of P450 AmphL from Streptomyces nodosus provides insights into substrate selectivity of polyene macrolide antibiotic biosynthetic P450s.
J.Biol.Chem., 298, 2022
6WE6
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BU of 6we6 by Molmil
Camphor bound P450cam D251E structure
Descriptor: CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ...
Authors:Amaya, J.A, Poulos, T.L, Batabyal, D.
Deposit date:2020-04-01
Release date:2020-07-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Proton Relay Network in the Bacterial P450s: CYP101A1 and CYP101D1.
Biochemistry, 59, 2020
6WFL
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BU of 6wfl by Molmil
Camphor soaked P450cam D251E
Descriptor: 5-EXO-HYDROXYCAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ...
Authors:Amaya, J.A, Poulos, T.L, Batabyal, D.
Deposit date:2020-04-03
Release date:2020-07-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Proton Relay Network in the Bacterial P450s: CYP101A1 and CYP101D1.
Biochemistry, 59, 2020
6WGW
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BU of 6wgw by Molmil
CYP101D1 D259E Hydroxycamphor bound
Descriptor: 5-EXO-HYDROXYCAMPHOR, CAMPHOR, Cytochrome P450 101D1, ...
Authors:Amaya, J.A, Poulos, T.L, Batabyal, D.
Deposit date:2020-04-06
Release date:2020-07-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Proton Relay Network in the Bacterial P450s: CYP101A1 and CYP101D1.
Biochemistry, 59, 2020
6WPL
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BU of 6wpl by Molmil
Structure of Cytochrome P450tcu
Descriptor: 5-EXO-HYDROXYCAMPHOR, Cytochrome P-450cam, subunit of camphor 5-monooxygenase system, ...
Authors:Murarka, V.C, Batabyal, D, Amaya, J.A, Sevrioukova, I.F, Poulos, T.L.
Deposit date:2020-04-27
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Unexpected Differences between Two Closely Related Bacterial P450 Camphor Monooxygenases.
Biochemistry, 59, 2020
8FZ8
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BU of 8fz8 by Molmil
Structure of cytochrome P450sky2
Descriptor: Cytochrome P450, OCTANOIC ACID (CAPRYLIC ACID), PROTOPORPHYRIN IX CONTAINING FE
Authors:Murarka, V.C, Poulos, T.L.
Deposit date:2023-01-27
Release date:2024-02-07
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Biosynthesis of a new skyllamycin in Streptomyces nodosus : a cytochrome P450 forms an epoxide in the cinnamoyl chain.
Org.Biomol.Chem., 22, 2024
4QGN
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BU of 4qgn by Molmil
Human acireductone dioxygenase with iron ion and L-methionine in active center
Descriptor: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, ACETATE ION, CHLORIDE ION, ...
Authors:Milaczewska, A.M, Chruszcz, M, Petkowski, J.J, Niedzialkowska, E, Minor, W, Borowski, T.
Deposit date:2014-05-23
Release date:2015-05-27
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:On the Structure and Reaction Mechanism of Human Acireductone Dioxygenase.
Chemistry, 24, 2018

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