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2X7U
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Structures of human carbonic anhydrase II inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors.
分子名称: (9BETA,14BETA,17BETA)-17-HYDROXY-2-METHOXYESTRA-1,3,5(10)-TRIEN-3-YL SULFAMATE, CARBONIC ANHYDRASE 2, GLYCEROL, ...
著者Cozier, G.E, Leese, M.P, Lloyd, M.D, Baker, M.D, Thiyagarajan, N, Acharya, K.R, Potter, B.V.L.
登録日2010-03-03
公開日2010-03-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structures of Human Carbonic Anhydrase II/Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Non-Steroidal Inhibitors.
Biochemistry, 49, 2010
2XHM
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Crystal structure of AnCE-K26 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ANGIOTENSIN CONVERTING ENZYME, ...
著者Akif, M, Ntai, I, Sturrock, E.D, Isaac, R.E, Bachmann, B.O, Acharya, K.R.
登録日2010-06-18
公開日2010-07-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal Structure of a Phosphonotripeptide K-26 in Complex with Angiotensin Converting Enzyme Homologue (Ance) from Drosophila Melanogaster.
Biochem.Biophys.Res.Commun., 398, 2010
2XY9
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Human Angiotensin converting enzyme in complex with phosphinic tripeptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ...
著者Akif, M, Schwager, S.L, Anthony, C.S, Czarny, B, Beau, F, Dive, V, Sturrock, E.D, Acharya, K.R.
登録日2010-11-16
公開日2011-05-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Novel Mechanism of Inhibition of Human Angiotensin-I-Converting Enzyme (Ace) by a Highly Specific Phosphinic Tripeptide.
Biochem.J., 436, 2011
2XYD
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human Angiotenisn converting enzyme N-domain in complex with Phosphinic tripeptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, CHLORIDE ION, ...
著者Akif, M, Schwager, S.L, Anthony, C.S, Czarny, B, Beau, F, Dive, V, Sturrock, E.D, Acharya, K.R.
登録日2010-11-17
公開日2011-05-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Novel Mechanism of Inhibition of Human Angiotensin-I-Converting Enzyme (Ace) by a Highly Specific Phosphinic Tripeptide.
Biochem.J., 436, 2011
2XHL
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Structure of a functional derivative of Clostridium botulinum neurotoxin type B
分子名称: BOTULINUM NEUROTOXIN B HEAVY CHAIN, BOTULINUM NEUROTOXIN B LIGHT CHAIN, ZINC ION
著者Masuyer, G, Beard, M, Cadd, V.A, Chaddock, J.A, Acharya, K.R.
登録日2010-06-18
公開日2010-12-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and Activity of a Functional Derivative of Clostridium Botulinum Neurotoxin B.
J.Struct.Biol., 174, 2011
1QKQ
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CHARCOT-LEYDEN CRYSTAL PROTEIN - MANNOSE COMPLEX
分子名称: EOSINOPHIL LYSOPHOSPHOLIPASE, alpha-D-mannopyranose
著者Swaminathan, G.J, Leonidas, D.D, Acharya, K.R.
登録日1999-07-31
公開日2000-01-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Selective recognition of mannose by the human eosinophil Charcot-Leyden crystal protein (galectin-10): a crystallographic study at 1.8 A resolution.
Biochemistry, 38, 1999
2YDM
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Structural characterization of angiotensin-I converting enzyme in complex with a selenium analogue of captopril
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN CONVERTING ENZYME, CHLORIDE ION, ...
著者Akif, M, Masuyer, G, Schwager, S.L.U, Bhuyan, B.J, Mugesh, G, Sturrock, E.D, Acharya, K.R.
登録日2011-03-22
公開日2011-09-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural Characterization of Angiotensin-I Converting Enzyme in Complex with a Selenium Analogue of Captopril
FEBS J., 278, 2011
2Y6T
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Molecular Recognition of Chymotrypsin by the Serine Protease Inhibitor Ecotin from Yersinia pestis
分子名称: CHYMOTRYPSINOGEN A, ECOTIN, SULFATE ION
著者Clark, E.A, Walker, N, Ford, D.C, Cooper, I.A, Oyston, P.C.F, Acharya, K.R.
登録日2011-01-26
公開日2011-04-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Molecular Recognition of Chymotrypsin by the Serine Protease Inhibitor Ecotin from Yersinia Pestis.
J.Biol.Chem., 286, 2011
1UN5
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ARH-II, AN ANGIOGENIN/RNASE A CHIMERA
分子名称: ANGIOGENIN, CITRIC ACID
著者Holloway, D.E, Baker, M.D, Acharya, K.R.
登録日2003-09-04
公開日2004-02-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystallographic Studies on Structural Features that Determine the Enzymatic Specificity and Potency of Human Angiogenin: Thr44, Thr80 and Residues 38-41
Biochemistry, 43, 2004
1UN3
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CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT T44D
分子名称: ANGIOGENIN
著者Holloway, D.E, Chavali, G.B, Acharya, K.R.
登録日2003-09-04
公開日2004-02-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystallographic Studies on Structural Features that Determine the Enzymatic Specificity and Potency of Human Angiogenin: Thr44, Thr80 and Residues 38-41
Biochemistry, 43, 2004
1UN4
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CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT T80A
分子名称: ANGIOGENIN, CITRIC ACID
著者Holloway, D.E, Chavali, G.B, Acharya, K.R.
登録日2003-09-04
公開日2004-02-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic Studies on Structural Features that Determine the Enzymatic Specificity and Potency of Human Angiogenin: Thr44, Thr80 and Residues 38-41
Biochemistry, 43, 2004
1UUP
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Crystal Structure of A Dimeric Form of Streptococcal Pyrogenic Exotoxin A (SpeA1).
分子名称: EXOTOXIN TYPE A, ZINC ION
著者Baker, M.D, Gendlina, I, Collins, C.M, Acharya, K.R.
登録日2004-01-08
公開日2004-08-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of a Dimeric Form of Streptococcal Pyrogenic Exotoxin a (Spea1)
Protein Sci., 13, 2004
6QS1
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Crystal structure of human Angiotensin-1 converting enzyme N-domain in complex with BPPb
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Cozier, G.E, Acharya, K.R.
登録日2019-02-20
公開日2019-05-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the C-domain-selective angiotensin-converting enzyme inhibition by bradykinin-potentiating peptide b (BPPb).
Biochem.J., 476, 2019
6S1Z
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Crystal structure of Anopheles gambiae AnoACE2 in complex with fosinoprilat
分子名称: Angiotensin-converting enzyme, ZINC ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Cozier, G.E, Acharya, K.R, Cashman, J.S.
登録日2019-06-19
公開日2019-11-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of angiotensin-converting enzyme from Anopheles gambiae in its native form and with a bound inhibitor.
Biochem.J., 476, 2019
6S1Y
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Crystal structure of Anopheles gambiae AnoACE2 in complex with gamma-Polyglutamic Acid.
分子名称: (2~{S})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]pentanedioic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Cozier, G.E, Acharya, K.R, Cashman, J.S.
登録日2019-06-19
公開日2019-11-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of angiotensin-converting enzyme from Anopheles gambiae in its native form and with a bound inhibitor.
Biochem.J., 476, 2019
6SH2
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Crystal structure of human neprilysin E584D in complex with C-type natriuretic peptide.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type natriuretic peptide fragment (CNP), CHLORIDE ION, ...
著者Moss, S, Subramanian, V, Acharya, K.R.
登録日2019-08-05
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of peptide-bound neprilysin reveals key binding interactions.
Febs Lett., 594, 2020
1AFK
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CRYSTAL STRUCTURE OF RIBONUCLEASE A IN COMPLEX WITH 5'-DIPHOSPHOADENOSINE-3'-PHOSPHATE
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, RIBONUCLEASE A
著者Leonidas, D.D, Acharya, K.R.
登録日1997-03-08
公開日1998-03-18
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution.
Biochemistry, 36, 1997
1A4Y
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RIBONUCLEASE INHIBITOR-ANGIOGENIN COMPLEX
分子名称: ANGIOGENIN, RIBONUCLEASE INHIBITOR
著者Papageorgiou, A.C, Acharya, K.R.
登録日1998-02-08
公開日1998-10-14
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular recognition of human angiogenin by placental ribonuclease inhibitor--an X-ray crystallographic study at 2.0 A resolution.
EMBO J., 16, 1997
1AFU
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STRUCTURE OF RIBONUCLEASE A AT 2.0 ANGSTROMS FROM MONOCLINIC CRYSTALS
分子名称: RIBONUCLEASE A
著者Leonidas, D.D, Acharya, K.R.
登録日1997-03-14
公開日1998-03-18
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution.
Biochemistry, 36, 1997
1ABB
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BU of 1abb by Molmil
CONTROL OF PHOSPHORYLASE B CONFORMATION BY A MODIFIED COFACTOR: CRYSTALLOGRAPHIC STUDIES ON R-STATE GLYCOGEN PHOSPHORYLASE RECONSTITUTED WITH PYRIDOXAL 5'-DIPHOSPHATE
分子名称: GLYCOGEN PHOSPHORYLASE B, INOSINIC ACID, PYRIDOXAL-5'-DIPHOSPHATE, ...
著者Leonidas, D.D, Oikonomakos, N.G, Papageorgiou, A.C, Acharya, K.R, Barford, D, Johnson, L.N.
登録日1992-04-09
公開日1993-10-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate.
Protein Sci., 1, 1992
1K58
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Crystal Structure of Human Angiogenin Variant D116H
分子名称: Angiogenin
著者Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R.
登録日2001-10-10
公開日2002-03-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1K59
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Crystal Structure of Human Angiogenin Variant Q117G
分子名称: CITRIC ACID, angiogenin
著者Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R.
登録日2001-10-10
公開日2002-03-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1K5B
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Crystal Structure of Human Angiogenin Variant des(121-123)
分子名称: Angiogenin, CITRIC ACID
著者Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R.
登録日2001-10-10
公開日2002-03-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1K5A
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Crystal structure of human angiogenin double variant I119A/F120A
分子名称: Angiogenin
著者Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R.
登録日2001-10-10
公開日2002-03-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1AFL
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RIBONUCLEASE A IN COMPLEX WITH 5'-DIPHOSPHOADENOSINE 2'-PHOSPHATE AT 1.7 ANGSTROM RESOLUTION
分子名称: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, RIBONUCLEASE A
著者Leonidas, D.D, Acharya, K.R.
登録日1997-03-08
公開日1998-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution.
Biochemistry, 36, 1997

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