1LPA
 
 | | INTERFACIAL ACTIVATION OF THE LIPASE-PROCOLIPASE COMPLEX BY MIXED MICELLES REVEALED BY X-RAY CRYSTALLOGRAPHY | | 分子名称: | CALCIUM ION, COLIPASE, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | 著者 | Van Tilbeurgh, H, Egloff, M.-P, Cambillau, C. | | 登録日 | 1994-08-19 | | 公開日 | 1994-11-01 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | | 主引用文献 | Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-ray crystallography.
Nature, 362, 1993
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1H99
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1N8S
 | | Structure of the pancreatic lipase-colipase complex | | 分子名称: | Triacylglycerol lipase, pancreatic, colipase II | | 著者 | van Tilbeurgh, H, Sarda, L, Verger, R, Cambillau, C. | | 登録日 | 2002-11-21 | | 公開日 | 2002-12-18 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | | 主引用文献 | Structure of the pancreatic lipase-procolipase complex
Nature, 359, 1992
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1B56
 | | HUMAN RECOMBINANT EPIDERMAL FATTY ACID BINDING PROTEIN | | 分子名称: | FATTY ACID BINDING PROTEIN, PALMITIC ACID | | 著者 | Van Tilbeurgh, H, Hohoff, C, Borchers, T, Spener, F. | | 登録日 | 1999-01-12 | | 公開日 | 1999-10-05 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Expression, purification, and crystal structure determination of recombinant human epidermal-type fatty acid binding protein.
Biochemistry, 38, 1999
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1H54
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1LPB
 | | THE 2.46 ANGSTROMS RESOLUTION STRUCTURE OF THE PANCREATIC LIPASE COLIPASE COMPLEX INHIBITED BY A C11 ALKYL PHOSPHONATE | | 分子名称: | CALCIUM ION, COLIPASE, LIPASE, ... | | 著者 | Egloff, M.-P, Van Tilbeurgh, H, Cambillau, C. | | 登録日 | 1994-08-19 | | 公開日 | 1994-11-01 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | The 2.46 A resolution structure of the pancreatic lipase-colipase complex inhibited by a C11 alkyl phosphonate.
Biochemistry, 34, 1995
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5DCQ
 | | Crystal structure of bacterial adhesin, FNE from Streptococcus equi spp. equi. | | 分子名称: | FORMIC ACID, Fibronectin-binding protein, artificial repeat proteins (alphaREP3) | | 著者 | Tiouajni, M, Graille, M, van Tilbeurgh, H. | | 登録日 | 2015-08-24 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structural and functional analysis of the fibronectin-binding protein FNE from Streptococcus equi spp. equi.
FEBS J., 281, 2014
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6ZUQ
 | | Crystal structure of the effector Ecp11-1 from Fulvia fulva | | 分子名称: | Extracellular protein 11-1, GLYCEROL, ZINC ION | | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | | 登録日 | 2020-07-23 | | 公開日 | 2021-08-04 | | 最終更新日 | 2022-07-27 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
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6ZUS
 | | Crystal structure of the effector Ecp11-1 from Fulvia fulva | | 分子名称: | DI(HYDROXYETHYL)ETHER, Extracellular protein 11-1, GLYCEROL, ... | | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | | 登録日 | 2020-07-23 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
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7AD5
 | | Crystal structure of the effector AvrLm5-9 from Leptosphaeria maculans | | 分子名称: | ACETATE ION, Avirulence protein LmJ1, GLYCEROL, ... | | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | | 登録日 | 2020-09-14 | | 公開日 | 2021-10-06 | | 最終更新日 | 2022-07-27 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
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6XUI
 | | Crystal structure of human phosphoglucose isomerase in complex with inhibitor | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 5-PHOSPHOARABINONIC ACID, GLYCEROL, ... | | 著者 | Li de la Sierra-Gallay, I, Ahmad, L, Plancqueel, S, van Tilbeurgh, H, Salmon, L. | | 登録日 | 2020-01-20 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Novel N-substituted 5-phosphate-d-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: Synthesis, structure-activity relationship and crystallographic studies.
Bioorg.Chem., 102, 2020
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5MTZ
 | | Crystal structure of a long form RNase Z from yeast | | 分子名称: | PHOSPHATE ION, Ribonuclease Z, ZINC ION | | 著者 | Li de la Sierra-Gallay, I, Miao, M, van Tilbeurgh, H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-06-21 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | The crystal structure of Trz1, the long form RNase Z from yeast.
Nucleic Acids Res., 45, 2017
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6XUH
 | | Crystal structure of human phosphoglucose isomerase in complex with inhibitor | | 分子名称: | (2R,3R,4S)-5-((2-aminoethyl)amino)-2,3,4-trihydroxy-5-oxopentyl dihydrogen phosphate, 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase | | 著者 | Li de la Sierra-Gallay, I, Ahmad, L, Plancqueel, S, van Tilbeurgh, H, Salmon, L. | | 登録日 | 2020-01-20 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Novel N-substituted 5-phosphate-d-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: Synthesis, structure-activity relationship and crystallographic studies.
Bioorg.Chem., 102, 2020
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7B76
 | | Crystal structure of the effector AvrLm5-9 from Leptosphaeria maculans | | 分子名称: | Avirulence protein LmJ1, IODIDE ION | | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | | 登録日 | 2020-12-09 | | 公開日 | 2022-01-12 | | 最終更新日 | 2023-03-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
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5CM2
 | | Structure of Y. lipolytica Trm9-Trm112 complex, a methyltransferase modifying U34 in the anticodon loop of some tRNAs | | 分子名称: | TRNA METHYLTRANSFERASE, TRNA METHYLTRANSFERASE ACTIVATOR SUBUNIT, ZINC ION | | 著者 | Letoquart, J, van Tran, N, Caroline, V, Aleksandrov, A, Lazar, N, Van Tilbeurgh, H, Liger, D, Graille, M. | | 登録日 | 2015-07-16 | | 公開日 | 2015-10-21 | | 最終更新日 | 2021-03-17 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure.
Nucleic Acids Res., 43, 2015
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2ZBK
 | | Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms | | 分子名称: | RADICICOL, Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit A | | 著者 | Graille, M, Cladiere, L, Durand, D, Lecointe, F, Forterre, P, van Tilbeurgh, H, Paris-Sud Yeast Structural Genomics (YSG) | | 登録日 | 2007-10-22 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.56 Å) | | 主引用文献 | Crystal Structure of an Intact Type II DNA Topoisomerase: Insights into DNA Transfer Mechanisms
Structure, 16, 2008
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6S84
 | | TsaBDE complex from Thermotoga maritima | | 分子名称: | ATPase YjeE, predicted to have essential role in cell wall biosynthesis, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... | | 著者 | Missoury, S, Li-de-La-Sierra-Gallay, I, van Tilbeurgh, H. | | 登録日 | 2019-07-08 | | 公開日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | The structure of the TsaB/TsaD/TsaE complex reveals an unexpected mechanism for the bacterial t6A tRNA-modification.
Nucleic Acids Res., 46, 2018
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6SX4
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6SWZ
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6Z81
 | | TsaBD bound to the inhibitor | | 分子名称: | (2~{S},3~{R})-2-[2-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]ethanoylamino]-3-oxidanyl-butanoic acid, ACETATE ION, ADENOSINE MONOPHOSPHATE, ... | | 著者 | Missoury, S, Van Tilbeurgh, H. | | 登録日 | 2020-06-02 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structure of a reaction intermediate mimic in t6A biosynthesis bound in the active site of the TsaBD heterodimer from Escherichia coli.
Nucleic Acids Res., 49, 2021
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6F89
 | | Structure of H234A/Y235A P.abyssi Sua5 | | 分子名称: | BICARBONATE ION, THREONINE, Threonylcarbamoyl-AMP synthase | | 著者 | Pichard-Kostuch, A, Zhang, W, Liger, D, Daugeron, M.C, Letoquart, J, Li de la Sierra-Gallay, I, Forterre, P, Collinet, B, van Tilbeurgh, H, Basta, T. | | 登録日 | 2017-12-12 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification.
RNA, 24, 2018
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6F87
 | | Crystal structure of P. abyssi Sua5 complexed with L-threonine and PPi | | 分子名称: | PYROPHOSPHATE 2-, THREONINE, Threonylcarbamoyl-AMP synthase | | 著者 | Pichard-Kostuch, A, Zhang, W, Liger, D, Daugeron, M.C, Letoquart, J, Li de la Sierra-Gallay, I, Forterre, P, Collinet, B, van Tilbeurgh, H, Basta, T. | | 登録日 | 2017-12-12 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification.
RNA, 24, 2018
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6F8Y
 | | Crystal structure of P. abyssi Sua5 complexed with L-threonine | | 分子名称: | THREONINE, Threonylcarbamoyl-AMP synthase | | 著者 | Pichard-Kostuch, A, Zhang, W, Liger, D, Daugeron, M.C, Letoquart, J, Li de la Sierra-Gallay, I, Forterre, P, Collinet, B, van Tilbeurgh, H, Basta, T. | | 登録日 | 2017-12-13 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification.
RNA, 24, 2018
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6FJ1
 | | Structure of the Ldtfm-avibactam carbamoyl enzyme | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 3,6,9,12,15-PENTAOXAHEPTADECANE, CHLORIDE ION, ... | | 著者 | Li de la Sierra Gallay, I, Iannazzo, L, Compain, F, Fonvielle, M, van Tilbeurgh, H, Edoo, Z, Arthur, M, Etheve-Quelquejeu, M, Hugonnet, J. | | 登録日 | 2018-01-19 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Synthesis of Avibactam Derivatives and Activity on beta-Lactamases and Peptidoglycan Biosynthesis Enzymes of Mycobacteria.
Chemistry, 24, 2018
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4WW9
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