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6IYR
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BU of 6iyr by Molmil
Crystal Structure of the acyltransferase domain from module 8 of the salinomycin polyketide synthase
Descriptor: PHOSPHATE ION, Type I modular polyketide synthase
Authors:Zhang, F, Zheng, J.
Deposit date:2018-12-17
Release date:2019-07-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Insights into the Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase.
Biochemistry, 58, 2019
6L3M
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BU of 6l3m by Molmil
Crystal Structure of the acyltransferase domain from the third module of the ansamitocin polyketide synthase
Descriptor: 2-methoxypropanedioic acid, GLYCEROL, PHOSPHATE ION, ...
Authors:Zhang, F, Zheng, J.
Deposit date:2019-10-11
Release date:2019-12-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural and Biochemical Insight into the Recruitment of Acyl Carrier Protein-Linked Extender Units in Ansamitocin Biosynthesis.
Chembiochem, 21, 2020
6L3N
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BU of 6l3n by Molmil
Crystal Structure of the acyltransferase domain from the third module of the ansamitocin polyketide synthase
Descriptor: GLYCEROL, METHYLMALONIC ACID, PHOSPHATE ION, ...
Authors:Zhang, F, Zheng, J.
Deposit date:2019-10-11
Release date:2019-12-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural and Biochemical Insight into the Recruitment of Acyl Carrier Protein-Linked Extender Units in Ansamitocin Biosynthesis.
Chembiochem, 21, 2020
7EDR
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BU of 7edr by Molmil
The crystal structure of the FERM and C-terminal domain complex of Drosophila Merlin
Descriptor: Moesin/ezrin/radixin homolog 2
Authors:Zhang, F, Long, J, Zhou, H.
Deposit date:2021-03-16
Release date:2021-04-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.527 Å)
Cite:The crystal structure of the FERM and C-terminal domain complex of Drosophila Merlin.
Biochem.Biophys.Res.Commun., 553, 2021
7F0W
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BU of 7f0w by Molmil
Crystal structure of KRAS-G12D bound to GDP with switch 1 open conformation
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION
Authors:Zhang, F.
Deposit date:2021-06-07
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Crystal structure of KRAS-G12D bound to GDP with switch 1 open conformation
To Be Published
4RQW
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BU of 4rqw by Molmil
Crystal structure of Myc3 N-terminal JAZ-binding domain [44-238] from Arabidopsis
Descriptor: CALCIUM ION, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J, Zhou, M, Xu, H.E, Melcher, K, He, S.Y.
Deposit date:2014-11-05
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RRU
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BU of 4rru by Molmil
Myc3 N-terminal JAZ-binding domain[5-242] from arabidopsis
Descriptor: CALCIUM ION, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J.S, Zhou, M, Xu, H.E, Melcher, K, He, S.Y.
Deposit date:2014-11-06
Release date:2015-08-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RS9
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BU of 4rs9 by Molmil
Structure of Myc3 N-terminal JAZ-binding domain [44-238] in complex with Jas motif of JAZ9
Descriptor: Protein TIFY 7, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J.S, Zhou, M, Xu, H.E, Melcher, K, He, S.Y.
Deposit date:2014-11-07
Release date:2015-08-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4YWC
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BU of 4ywc by Molmil
Crystal structure of Myc3(5-242) fragment in complex with Jaz9(218-239) peptide
Descriptor: Protein TIFY 7, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Brunzelle, J.S, Xu, H.E, Melcher, K, He, S.Y.
Deposit date:2015-03-20
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4YZ6
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BU of 4yz6 by Molmil
Crystal Structure of Myc3[44-238] from Arabidopsis in complex with Jaz1 peptide [200-221]
Descriptor: Protein TIFY 10A, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Brunzelle, J, Xu, H.E, Melcher, K, HE, S.Y.
Deposit date:2015-03-24
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
3H4P
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BU of 3h4p by Molmil
Proteasome 20S core particle from Methanocaldococcus jannaschii
Descriptor: Proteasome subunit alpha, Proteasome subunit beta
Authors:Jeffrey, P.D, Zhang, F, Hu, M, Tian, G, Zhang, P, Finley, D, Shi, Y.
Deposit date:2009-04-20
Release date:2009-06-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii.
Mol.Cell, 34, 2009
3H4M
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BU of 3h4m by Molmil
AAA ATPase domain of the proteasome- activating nucleotidase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Proteasome-activating nucleotidase
Authors:Jeffrey, P, Zhang, F, Hu, M, Tian, G, Zhang, P, Finley, D, Shi, Y.
Deposit date:2009-04-20
Release date:2009-06-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii.
Mol.Cell, 34, 2009
3H43
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BU of 3h43 by Molmil
N-terminal domain of the proteasome-activating nucleotidase of Methanocaldococcus jannaschii
Descriptor: Proteasome-activating nucleotidase
Authors:Jeffrey, P.D, Zhang, F, Hu, M, Tian, G, Zhang, P, Finley, D, Shi, Y.
Deposit date:2009-04-17
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii.
Mol.Cell, 34, 2009
5KCM
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BU of 5kcm by Molmil
Crystal structure of iron-sulfur cluster containing photolyase PhrB mutant I51W
Descriptor: (6-4) photolyase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Yang, X, Bowatte, K, Zhang, F, Lamparter, T.
Deposit date:2016-06-06
Release date:2017-01-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.149 Å)
Cite:Crystal Structures of Bacterial (6-4) Photolyase Mutants with Impaired DNA Repair Activity.
Photochem. Photobiol., 93, 2017
5LFA
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BU of 5lfa by Molmil
Crystal structure of iron-sulfur cluster containing bacterial (6-4) photolyase PhrB - Y424F mutant with impaired DNA repair activity
Descriptor: (6-4) photolyase, 1-deoxy-1-(6,7-dimethyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Kwiatkowski, D, Zhang, F, Krauss, N, Lamparter, T, Scheerer, P.
Deposit date:2016-06-30
Release date:2017-01-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Bacterial (6-4) Photolyase Mutants with Impaired DNA Repair Activity.
Photochem. Photobiol., 93, 2017
1PYE
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BU of 1pye by Molmil
Crystal structure of CDK2 with inhibitor
Descriptor: Cell division protein kinase 2, [2-AMINO-6-(2,6-DIFLUORO-BENZOYL)-IMIDAZO[1,2-A]PYRIDIN-3-YL]-PHENYL-METHANONE
Authors:Zhang, F, Hamdouchi, C.
Deposit date:2003-07-08
Release date:2004-07-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines.
MOL.CANCER THER., 3, 2004
1PY5
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BU of 1py5 by Molmil
Crystal Structure of TGF-beta receptor I kinase with inhibitor
Descriptor: 4-(3-PYRIDIN-2-YL-1H-PYRAZOL-4-YL)QUINOLINE, SULFATE ION, TGF-beta receptor type I
Authors:Zhang, F, Sawyer, J.S.
Deposit date:2003-07-08
Release date:2004-07-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain.
Bioorg.Med.Chem.Lett., 14, 2004
1RW8
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BU of 1rw8 by Molmil
Crystal Structure of TGF-beta receptor I kinase with ATP site inhibitor
Descriptor: 3-(4-FLUOROPHENYL)-2-(6-METHYLPYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOLE, TGF-beta receptor type I
Authors:Zhang, F, Sawyer, J.S.
Deposit date:2003-12-16
Release date:2005-02-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain.
Bioorg.Med.Chem.Lett., 14, 2004
4DJA
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BU of 4dja by Molmil
Crystal structure of a prokaryotic (6-4) photolyase PhrB from Agrobacterium Tumefaciens with an Fe-S cluster and a 6,7-dimethyl-8-ribityllumazine antenna chromophore at 1.45A resolution
Descriptor: 1-deoxy-1-(6,7-dimethyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Scheerer, P, Zhang, F, Oberpichler, I, Lamparter, T, Krauss, N.
Deposit date:2012-02-01
Release date:2013-04-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of a prokaryotic (6-4) photolyase with an Fe-S cluster and a 6,7-dimethyl-8-ribityllumazine antenna chromophore.
Proc.Natl.Acad.Sci.USA, 110, 2013
5T0Q
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BU of 5t0q by Molmil
Crystal structure of the Myc3 N-terminal domain [44-242] in complex with JAZ10 Jas domain [166-192] from arabidopsis
Descriptor: Protein TIFY 9, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Brunzelle, J.S, He, S.Y, Xu, H.E, Melcher, K.
Deposit date:2016-08-16
Release date:2017-01-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural insights into alternative splicing-mediated desensitization of jasmonate signaling.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5T0F
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BU of 5t0f by Molmil
Crystal structure of the Myc3 N-terminal domain [44-242] in complex with JAZ10 CMID domain [16-58] from arabidopsis
Descriptor: Protein TIFY 9, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Brunzelle, J.S, He, S.Y, Xu, H.E, Melcher, K.
Deposit date:2016-08-16
Release date:2017-01-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into alternative splicing-mediated desensitization of jasmonate signaling.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6DKL
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BU of 6dkl by Molmil
Crystal Structure of a Rationally Designed Six-Fold Symmetric DNA Scaffold
Descriptor: DNA (5'-D(P*CP*AP*CP*AP*CP*CP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*GP*AP*TP*GP*CP*AP*CP*A)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*GP*AP*TP*CP*CP*AP*G)-3'), ...
Authors:Simmons, C.R, Zhang, F, Yan, H.
Deposit date:2018-05-29
Release date:2018-08-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.034 Å)
Cite:Self-Assembly of a 3D DNA Crystal Structure with Rationally Designed Six-Fold Symmetry.
Angew. Chem. Int. Ed. Engl., 57, 2018
4IU6
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BU of 4iu6 by Molmil
Human Methionine Aminopeptidase in complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1
Descriptor: 4-[4-(4-methoxyphenyl)piperazin-1-yl]-2-(pyridin-2-yl)quinazoline, COBALT (II) ION, Methionine aminopeptidase 1, ...
Authors:Gabelli, S.B, Zhang, F, Miller, M, Liu, J, Amzel, L.M.
Deposit date:2013-01-19
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells.
J.Med.Chem., 56, 2013
5UMO
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BU of 5umo by Molmil
STRUCTURE OF EXTRACELLULAR SIGNAL-REGULATED KINASE
Descriptor: Mitogen-activated protein kinase 1, SULFATE ION
Authors:CHLEBOWICZ, J, ZHANG, F, GOLDSMITH, E.J.
Deposit date:2017-01-27
Release date:2017-03-01
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Atomic structure of the MAP kinase ERK2 at 2.3 A resolution.
Nature, 367, 1994
5XXY
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BU of 5xxy by Molmil
Crystal structure of PD-L1 complexed with atezolizumab fab at 2.9A
Descriptor: Programmed cell death 1 ligand 1, heavy chain of atezolizumab fab, light chain of atezolizumab fab
Authors:Zhou, A, Zhang, F.
Deposit date:2017-07-05
Release date:2017-09-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the therapeutic anti-PD-L1 antibody atezolizumab.
Oncotarget, 8, 2017

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