5YGP
| Human TNFRSF25 death domain mutant-D412E | 分子名称: | SULFATE ION, TNFRSF25 death domain, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Yin, X, Jin, T.C. | 登録日 | 2017-09-25 | 公開日 | 2018-10-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure and activation mechanism of DR3 death domain. Febs J., 286, 2019
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4M65
| In situ thermolysin crystallized on a MiTeGen micromesh with asparagine ligand | 分子名称: | 1,2-ETHANEDIOL, ASPARAGINE, CALCIUM ION, ... | 著者 | Yin, X, Scalia, A, Leroy, L, Cuttitta, C.M, Polizzo, G.M, Ericson, D.L, Roessler, C.G, Campos, O, Agarwal, R, Allaire, M, Orville, A.M, Jackimowicz, R, Ma, M.Y, Sweet, R.M, Soares, A.S. | 登録日 | 2013-08-08 | 公開日 | 2013-10-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Hitting the target: fragment screening with acoustic in situ
co-crystallization of proteins plus fragment libraries on
pin-mounted data-collection micromeshes Acta Crystallogr.,Sect.D, D70
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4N8Z
| In situ lysozyme crystallized on a MiTeGen micromesh with benzamidine ligand | 分子名称: | BENZAMIDINE, CHLORIDE ION, Lysozyme C, ... | 著者 | Yin, X, Scalia, A, Leroy, L, Cuttitta, C.M, Polizzo, G.M, Ericson, D.L, Roessler, C.G, Campos, O, Agarwal, R, Allaire, M, Orville, A.M, Jackimowicz, R, Ma, M.Y, Sweet, R.M, Soares, A.S. | 登録日 | 2013-10-18 | 公開日 | 2013-10-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes. Acta Crystallogr.,Sect.D, 70, 2014
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4NCY
| In situ trypsin crystallized on a MiTeGen micromesh with imidazole ligand | 分子名称: | 1,2-ETHANEDIOL, BENZAMIDINE, CALCIUM ION, ... | 著者 | Yin, X, Scalia, A, Leroy, L, Cuttitta, C.M, Polizzo, G.M, Ericson, D.L, Roessler, C.G, Campos, O, Agarwal, R, Allaire, M, Orville, A.M, Jackimowicz, R, Ma, M.Y, Sweet, R.M, Soares, A.S. | 登録日 | 2013-10-25 | 公開日 | 2014-04-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes. Acta Crystallogr.,Sect.D, 70, 2014
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5Y3R
| Cryo-EM structure of Human DNA-PK Holoenzyme | 分子名称: | DNA (34-MER), DNA (36-MER), DNA-dependent protein kinase catalytic subunit, ... | 著者 | Yin, X, Liu, M, Tian, Y, Wang, J, Xu, Y. | 登録日 | 2017-07-29 | 公開日 | 2017-09-06 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Cryo-EM structure of human DNA-PK holoenzyme Cell Res., 27, 2017
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5YEV
| Murine DR3 death domain | 分子名称: | SULFATE ION, TNFRSF25 death domain | 著者 | Yin, X, Jin, T. | 登録日 | 2017-09-19 | 公開日 | 2018-09-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure and activation mechanism of DR3 death domain. Febs J., 286, 2019
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5YGS
| Human TNFRSF25 death domain | 分子名称: | Human TNRSF25 death domain, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Yin, X, Jin, T. | 登録日 | 2017-09-26 | 公開日 | 2018-10-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.691 Å) | 主引用文献 | Crystal structure and activation mechanism of DR3 death domain. Febs J., 286, 2019
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5ZNY
| Structure of mDR3_DD-C363G with MBP tag | 分子名称: | Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25, SULFATE ION | 著者 | Yin, X, Jin, T. | 登録日 | 2018-04-11 | 公開日 | 2019-04-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Crystal structure and activation mechanism of DR3 death domain. Febs J., 286, 2019
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7EMF
| Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation | 分子名称: | Isoform 2 of Mediator of RNA polymerase II transcription subunit 16, Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, ... | 著者 | Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. | 登録日 | 2021-04-13 | 公開日 | 2021-05-05 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
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7ENJ
| Human Mediator (deletion of MED1-IDR) in a Tail-bent conformation (MED-B) | 分子名称: | Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ... | 著者 | Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. | 登録日 | 2021-04-17 | 公開日 | 2021-05-19 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
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5ZNZ
| Structure of mDR3 DD with MBP tag mutant-I387V | 分子名称: | Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25, SULFATE ION | 著者 | Jin, T, Yin, X. | 登録日 | 2018-04-12 | 公開日 | 2019-04-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure and activation mechanism of DR3 death domain. Febs J., 286, 2019
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4U7P
| Crystal structure of DNMT3A-DNMT3L complex | 分子名称: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Wang, L, Guo, X, Li, J, Xiao, J, Yin, X, He, S, Wang, J, Xu, Y. | 登録日 | 2014-07-31 | 公開日 | 2014-11-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.821 Å) | 主引用文献 | Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
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4U7T
| Crystal structure of DNMT3A-DNMT3L in complex with histone H3 | 分子名称: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Guo, X, Wang, L, Yin, X, Li, J, Xiao, J, He, S, Wang, J, Xu, Y. | 登録日 | 2014-07-31 | 公開日 | 2014-11-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
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1P2A
| The structure of cyclin dependent kinase 2 (CKD2) with a trisubstituted naphthostyril inhibitor | 分子名称: | 5-[(2-AMINOETHYL)AMINO]-6-FLUORO-3-(1H-PYRROL-2-YL)BENZO[CD]INDOL-2(1H)-ONE, Cell division protein kinase 2 | 著者 | Liu, J.-J, Dermatakis, A, Lukacs, C.M, Konzelmann, F, Chen, Y, Kammlott, U, Depinto, W, Yang, H, Yin, X, Chen, Y, Schutt, A, Simcox, M.E, Luk, K.-C. | 登録日 | 2003-04-15 | 公開日 | 2003-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | 3,5,6-Trisubstituted Naphthostyrils as CDK2 Inhibitors BIOORG.MED.CHEM., 13, 2003
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8GXQ
| PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y. | 登録日 | 2022-09-21 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (5.04 Å) | 主引用文献 | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
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8GXS
| PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X. | 登録日 | 2022-09-21 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
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5XBM
| Structure of SCARB2-JL2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosome membrane protein 2, ... | 著者 | Zhang, X, Yang, P, Wang, N, Zhang, J, Li, J, Guo, H, Yin, X, Rao, Z, Wang, X, Zhang, L. | 登録日 | 2017-03-20 | 公開日 | 2018-06-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.501 Å) | 主引用文献 | The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection. Protein Cell, 8, 2017
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7ENA
| TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | 登録日 | 2021-04-16 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (4.07 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
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7ENC
| TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | 登録日 | 2021-04-16 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
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7LG9
| ChsB1 | 分子名称: | 3-ketoacyl-ACP reductase | 著者 | Yuan, T, Werman, J.M, Yin, X, Yang, M, Garcia-Diaz, M, Sampson, N.S. | 登録日 | 2021-01-19 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Enzymatic beta-Oxidation of the Cholesterol Side Chain in Mycobacterium tuberculosis Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA. Acs Infect Dis., 7, 2021
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7LGB
| ChsB1 in complex with NAD+ | 分子名称: | 3-ketoacyl-ACP reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Yuan, T, Werman, J.M, Yin, X, Yang, M, Garcia-Diaz, M, Sampson, N.S. | 登録日 | 2021-01-19 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Enzymatic beta-Oxidation of the Cholesterol Side Chain in Mycobacterium tuberculosis Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA. Acs Infect Dis., 7, 2021
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7YF5
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5GPP
| Crystal structure of zebrafish ASC PYD domain | 分子名称: | ACETATE ION, Maltose-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, SULFATE ION, ... | 著者 | Jin, T, Li, Y. | 登録日 | 2016-08-04 | 公開日 | 2017-08-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Functional and structural characterization of zebrafish ASC. FEBS J., 285, 2018
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5GPQ
| Crystal Structure of zebrafish ASC CARD Domain | 分子名称: | CITRIC ACID, Maltose-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Jin, T, Li, Y. | 登録日 | 2016-08-04 | 公開日 | 2017-08-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional and structural characterization of zebrafish ASC. FEBS J., 285, 2018
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5GP1
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