6BIT
| SIRPalpha antibody complex | 分子名称: | KWAR23 Fab heavy chain, KWAR23 Fab light chain, Tyrosine-protein phosphatase non-receptor type substrate 1 | 著者 | Ring, N.G, Herndler-Brandstetter, D, Weiskopf, K, Shan, L, Volkmer, J.P, George, B.M, Lietzenmayer, M, McKenna, K.M, Naik, T.J, McCarty, A, Zheng, Y, Ring, A.M, Flavell, R.A, Weissman, I.L. | 登録日 | 2017-11-03 | 公開日 | 2017-12-06 | 最終更新日 | 2019-11-20 | 実験手法 | X-RAY DIFFRACTION (2.191 Å) | 主引用文献 | Anti-SIRP alpha antibody immunotherapy enhances neutrophil and macrophage antitumor activity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5IWL
| CD47-diabody complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5F9 diabody, Leukocyte surface antigen CD47, ... | 著者 | Di, W, Jude, K.M, Garcia, K.C. | 登録日 | 2016-03-22 | 公開日 | 2016-06-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. J.Clin.Invest., 126, 2016
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4KJY
| Complex of high-affinity SIRP alpha variant FD6 with CD47 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, High-affinity SIRPa variant FD6, Leukocyte surface antigen CD47, ... | 著者 | Ring, A.M, Ozkan, E, Ho, C.C.M, Garcia, K.C. | 登録日 | 2013-05-04 | 公開日 | 2013-06-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Engineered SIRP alpha variants as immunotherapeutic adjuvants to anticancer antibodies. Science, 341, 2013
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4Y5Y
| Diabody 330 complex with EpoR | 分子名称: | Erythropoietin receptor, GLYCEROL, diabody 330 VH domain, ... | 著者 | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | 登録日 | 2015-02-12 | 公開日 | 2015-03-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands. Cell, 160, 2015
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4Y5X
| Diabody 305 complex with EpoR | 分子名称: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, Erythropoietin receptor, ... | 著者 | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | 登録日 | 2015-02-12 | 公開日 | 2015-03-18 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands. Cell, 160, 2015
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4Y5V
| Diabody 305 complex with EpoR | 分子名称: | DI(HYDROXYETHYL)ETHER, Diabody 305 VL domain, Erythropoietin receptor, ... | 著者 | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | 登録日 | 2015-02-12 | 公開日 | 2015-04-29 | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | 主引用文献 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands. Cell, 160, 2015
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