6Z26
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7BJI
| Crystal structure of the Danio rerio centrosomal protein Cep135 coiled-coil fragment 64-190 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Centrosomal protein of 135 kDa, ... | Authors: | Li, Q, Hatzopoulos, G, Iller, O, Vakonakis, I. | Deposit date: | 2021-01-14 | Release date: | 2021-01-27 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Crystal structure of the Danio rerio centrosomal protein Cep135 coiled-coil fragment 64-190 To Be Published
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6SY0
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1M2E
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1M2F
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4GFC
| N-terminal coiled-coil dimer of C.elegans SAS-6, crystal form B | Descriptor: | 1,2-ETHANEDIOL, IMIDAZOLE, Spindle assembly abnormal protein 6, ... | Authors: | Erat, M.C, Vakonakis, I. | Deposit date: | 2012-08-03 | Release date: | 2013-06-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc.Natl.Acad.Sci.USA, 110, 2013
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4GFA
| N-terminal coiled-coil dimer of C.elegans SAS-6, crystal form A | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Spindle assembly abnormal protein 6 | Authors: | Erat, M.C, Vakonakis, I. | Deposit date: | 2012-08-03 | Release date: | 2013-06-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc.Natl.Acad.Sci.USA, 110, 2013
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4G79
| Structure a C. elegans SAS-6 variant | Descriptor: | GLYCEROL, Spindle assembly abnormal protein 6, TETRAETHYLENE GLYCOL | Authors: | Erat, M.C, Vakonakis, I. | Deposit date: | 2012-07-20 | Release date: | 2013-06-19 | Last modified: | 2017-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc.Natl.Acad.Sci.USA, 110, 2013
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4GEX
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4GEU
| Structure of a stabilised ceSAS-6 dimer | Descriptor: | GLYCEROL, Spindle assembly abnormal protein 6, TETRAETHYLENE GLYCOL | Authors: | Erat, M.C, Vakonakis, I. | Deposit date: | 2012-08-02 | Release date: | 2013-06-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc.Natl.Acad.Sci.USA, 110, 2013
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3EJH
| Crystal Structure of the Fibronectin 8-9FnI Domain Pair in Complex with a Type-I Collagen Peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen type-I a1 chain, Fibronectin, ... | Authors: | Erat, M.C, Lowe, E.D, Campbell, I.D, Vakonakis, I. | Deposit date: | 2008-09-18 | Release date: | 2009-02-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Identification and structural analysis of type I collagen sites in complex with fibronectin fragments. Proc.Natl.Acad.Sci.USA, 106, 2009
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3G9W
| Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ... | Authors: | Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D. | Deposit date: | 2009-02-15 | Release date: | 2009-10-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.165 Å) | Cite: | The structure of an integrin/talin complex reveals the basis of inside-out signal transduction Embo J., 28, 2009
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3GXE
| Complex of a Low Affinity Collagen Site with the Fibronectin 8-9FnI Domain Pair | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(I) chain, Fibronectin, ... | Authors: | Sladek, B, Campbell, I.D, Vakonakis, I. | Deposit date: | 2009-04-02 | Release date: | 2010-04-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural analysis of collagen type I interactions with human fibronectin reveals a cooperative binding mode J.Biol.Chem., 288, 2013
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6YRL
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6YRN
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6YS4
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6Z4A
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6ZHI
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7NQZ
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z1827898537 | Descriptor: | (3S)-N-benzylpyrrolidin-3-amine, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... | Authors: | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | Deposit date: | 2021-03-02 | Release date: | 2021-03-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.319 Å) | Cite: | Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
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7NQR
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z287256168 | Descriptor: | (S)-N-(1-cyclopropylethyl)-6-methylpicolinamide, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, AMP PHOSPHORAMIDATE, ... | Authors: | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | Deposit date: | 2021-03-02 | Release date: | 2021-03-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
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7NQU
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z396380540 | Descriptor: | AMP PHOSPHORAMIDATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | Deposit date: | 2021-03-02 | Release date: | 2021-03-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
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7NQS
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z1203107138 | Descriptor: | 1-ethyl-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide, AMP PHOSPHORAMIDATE, GLYCEROL, ... | Authors: | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | Deposit date: | 2021-03-02 | Release date: | 2021-03-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
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7OOG
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823 | Descriptor: | 4-bromanylpyridin-2-amine, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... | Authors: | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | Deposit date: | 2021-05-27 | Release date: | 2021-06-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823 To Be Published
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7OOE
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z321318226 | Descriptor: | AMP PHOSPHORAMIDATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | Deposit date: | 2021-05-27 | Release date: | 2021-06-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.369 Å) | Cite: | Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
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4JLE
| Structure of the P. falciparum PFI1780w PHIST domain | Descriptor: | ACETATE ION, CHLORIDE ION, PHIST | Authors: | Slater, L, Vakonakis, I. | Deposit date: | 2013-03-12 | Release date: | 2014-04-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | A Plasmodium falciparum PHIST protein binds the virulence factor PfEMP1 and comigrates to knobs on the host cell surface. Faseb J., 28, 2014
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