7TC0
| The structure of human ABCA1 in digitonin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ... | Authors: | Sun, Y, Li, X. | Deposit date: | 2021-12-22 | Release date: | 2022-01-26 | Last modified: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states. Nat Cardiovasc Res, 1, 2022
|
|
7TBY
| The structure of human ABCA1 in nanodisc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ... | Authors: | Sun, Y, Li, X. | Deposit date: | 2021-12-22 | Release date: | 2022-01-26 | Last modified: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states. Nat Cardiovasc Res, 1, 2022
|
|
4MYD
| 1.37 Angstrom Crystal Structure of E. Coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH) in complex with SHCHC | Descriptor: | 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | Authors: | Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z. | Deposit date: | 2013-09-27 | Release date: | 2014-04-23 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (1.374 Å) | Cite: | Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad. J.Biol.Chem., 289, 2014
|
|
4MXD
| 1.45 angstronm crystal structure of E.coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH) | Descriptor: | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z. | Deposit date: | 2013-09-26 | Release date: | 2014-04-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad. J.Biol.Chem., 289, 2014
|
|
4I42
| E.coli. 1,4-dihydroxy-2-naphthoyl coenzyme A synthase (ecMenB) in complex with 1-hydroxy-2-naphthoyl-CoA | Descriptor: | 1,2-ETHANEDIOL, 1,4-Dihydroxy-2-naphthoyl-CoA synthase, 1-hydroxy-2-naphthoyl-CoA, ... | Authors: | Sun, Y, Song, H, Li, J, Li, Y, Jiang, M, Zhou, J, Guo, Z. | Deposit date: | 2012-11-27 | Release date: | 2013-05-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.848 Å) | Cite: | Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamily Plos One, 8, 2013
|
|
4MYS
| 1.4 Angstrom Crystal Structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase with SHCHC and Pyruvate | Descriptor: | 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, GLYCEROL, ... | Authors: | Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z. | Deposit date: | 2013-09-28 | Release date: | 2014-04-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.423 Å) | Cite: | Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad. J.Biol.Chem., 289, 2014
|
|
2N1I
| |
7DRB
| Crystal structure of plant receptor like protein RXEG1 with xyloglucanase XEG1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cell 12A endoglucanase, ... | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | Deposit date: | 2020-12-27 | Release date: | 2022-06-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase. Nature, 610, 2022
|
|
7DRC
| Cryo-EM structure of plant receptor like protein RXEG1 in complex with xyloglucanase XEG1 and BAK1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Brassinosteroid insensitive 1-associated receptor kinase 1, ... | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | Deposit date: | 2020-12-27 | Release date: | 2022-06-22 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase. Nature, 610, 2022
|
|
4MG3
| Crystal Structural Analysis of 2A Protease from Coxsackievirus A16 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PENTAETHYLENE GLYCOL, Protease 2A, ... | Authors: | Sun, Y, Wang, X, Dang, M, Yuan, S. | Deposit date: | 2013-08-28 | Release date: | 2014-03-26 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | An open conformation determined by a structural switch for 2A protease from coxsackievirus A16. Protein Cell, 4, 2013
|
|
7W3V
| Plant receptor like protein RXEG1 in complex with xyloglucanase XEG1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cell 12A endoglucanase, ... | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | Deposit date: | 2021-11-26 | Release date: | 2022-06-22 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase. Nature, 610, 2022
|
|
7W3X
| Cryo-EM structure of plant receptor like protein RXEG1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Membrane-localized LRR receptor-like protein, ... | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | Deposit date: | 2021-11-26 | Release date: | 2022-06-22 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase. Nature, 610, 2022
|
|
7W3T
| Cryo-EM structure of plant receptor like kinase NbBAK1 in RXEG1-BAK1-XEG1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Brassinosteroid insensitive 1-associated receptor kinase 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | Deposit date: | 2021-11-26 | Release date: | 2022-06-22 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase. Nature, 610, 2022
|
|
7E5S
| SARS-CoV-2 S trimer with four-antibody cocktail complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | Authors: | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | Deposit date: | 2021-02-20 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms. Cell Res., 31, 2021
|
|
6BM0
| Cryo-EM structure of human CPSF-160-WDR33 complex at 3.8 A resolution | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33 | Authors: | Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L. | Deposit date: | 2017-11-12 | Release date: | 2017-11-22 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular basis for the recognition of the human AAUAAA polyadenylation signal. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6BLY
| Cryo-EM structure of human CPSF-160-WDR33 complex at 3.36A resolution | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33 | Authors: | Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L. | Deposit date: | 2017-11-12 | Release date: | 2017-11-22 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Molecular basis for the recognition of the human AAUAAA polyadenylation signal. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
7E5R
| SARS-CoV-2 S trimer with three-antibody cocktail complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | Authors: | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | Deposit date: | 2021-02-20 | Release date: | 2021-10-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms. Cell Res., 31, 2021
|
|
6O5K
| Murine TRIM28 Bbox1 domain | Descriptor: | Transcription intermediary factor 1-beta, ZINC ION | Authors: | Sun, Y, Keown, J.R, Goldstone, D.C. | Deposit date: | 2019-03-03 | Release date: | 2019-06-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family. J.Mol.Biol., 431, 2019
|
|
8HXQ
| Nanobody1 in complex with human BCMA ECD | Descriptor: | Nanobody1, Tumor necrosis factor receptor superfamily member 17 | Authors: | Sun, Y, Zhang, B. | Deposit date: | 2023-01-05 | Release date: | 2024-01-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity. Signal Transduct Target Ther, 8, 2023
|
|
8HXR
| Nanobody2 in complex with human BCMA ECD | Descriptor: | Nanobody2, Tumor necrosis factor receptor superfamily member 17 | Authors: | Sun, Y, Zhang, B. | Deposit date: | 2023-01-05 | Release date: | 2024-01-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity. Signal Transduct Target Ther, 8, 2023
|
|
8BCM
| |
6URG
| Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complex | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 4, ... | Authors: | Sun, Y, Zhang, Y, Walz, T, Tong, L. | Deposit date: | 2019-10-23 | Release date: | 2019-11-27 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery. Mol.Cell, 77, 2020
|
|
6URO
| Cryo-EM structure of human CPSF160-WDR33-CPSF30-PAS RNA-CstF77 complex | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, Cleavage stimulation factor subunit 3, ... | Authors: | Sun, Y, Zhang, Y, Walz, T, Tong, L. | Deposit date: | 2019-10-23 | Release date: | 2019-11-27 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery. Mol.Cell, 77, 2020
|
|
4M7E
| Structural insight into BL-induced activation of the BRI1-BAK1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1, ... | Authors: | Chai, J, Han, Z, Sun, Y. | Deposit date: | 2013-08-12 | Release date: | 2013-10-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.602 Å) | Cite: | Structural insight into BL-induced activation of the BRI1-BAK1 complex To be Published
|
|
4MNA
| Crystal structure of the free FLS2 ectodomains | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LRR receptor-like serine/threonine-protein kinase FLS2, ZINC ION | Authors: | Chai, J, Han, Z, Sun, Y. | Deposit date: | 2013-09-10 | Release date: | 2013-12-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.998 Å) | Cite: | Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex. Science, 342, 2013
|
|