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Crystal Structure of IRAK4 kinase in complex with a small molecule inhibitor
Descriptor:	Interleukin-1 receptor-associated kinase 4, N-(2-morpholin-4-yl-1,3-benzoxazol-6-yl)-6-pyridin-4-yl-pyridine-2-carboxamide
Authors:	Krishnamurthy, N.R, Anirudha, L.
Deposit date:	2020-05-09
Release date:	2020-11-25
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (3.2 Å)
Cite:	Discovery of CA-4948, an Orally Bioavailable IRAK4 Inhibitor for Treatment of Hematologic Malignancies. Acs Med.Chem.Lett., 11, 2020

Crystal structure of Androgen Receptor in complex with the ligand
Descriptor:	2-chloro-4-[(3S,3aS,4S)-4-hydroxy-3-methoxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-3-methylbenzonitrile, Androgen receptor
Authors:	Krishnamurthy, N, Sangeetha, R, Ghadiyaram, C, Sasmal, S, Subramanya, H.S.
Deposit date:	2014-06-11
Release date:	2015-06-17
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	3-alkoxy-pyrrolo[1,2-b]pyrazolines as selective androgen receptor modulators with ideal physicochemical properties for transdermal administration J.Med.Chem., 57, 2014