Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4QL8

Crystal structure of Androgen Receptor in complex with the ligand

Summary for 4QL8
Entry DOI10.2210/pdb4ql8/pdb
DescriptorAndrogen receptor, 2-chloro-4-[(3S,3aS,4S)-4-hydroxy-3-methoxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-3-methylbenzonitrile (3 entities in total)
Functional Keywordstranscription regulation, receptor, transcription
Biological sourceHomo sapiens (human)
Cellular locationNucleus: P10275
Total number of polymer chains1
Total formula weight30456.98
Authors
Krishnamurthy, N.,Sangeetha, R.,Ghadiyaram, C.,Sasmal, S.,Subramanya, H.S. (deposition date: 2014-06-11, release date: 2015-06-17, Last modification date: 2023-11-08)
Primary citationUllrich, T.,Sasmal, S.,Boorgu, V.,Pasagadi, S.,Cheera, S.,Rajagopalan, S.,Bhumireddy, A.,Shashikumar, D.,Chelur, S.,Belliappa, C.,Pandit, C.,Krishnamurthy, N.,Mukherjee, S.,Ramanathan, A.,Ghadiyaram, C.,Ramachandra, M.,Santos, P.G.,Lagu, B.,Bock, M.G.,Perrone, M.H.,Weiler, S.,Keller, H.
3-alkoxy-pyrrolo[1,2-b]pyrazolines as selective androgen receptor modulators with ideal physicochemical properties for transdermal administration
J.Med.Chem., 57:7396-7411, 2014
Cited by
PubMed: 25121964
DOI: 10.1021/jm5009049
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon