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2H64
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BU of 2h64 by Molmil
Crystal structure of a ternary ligand-receptor complex of BMP-2
Descriptor: Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
Authors:Mueller, T.D, Sebald, W, Weber, D.
Deposit date:2006-05-30
Release date:2007-04-10
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
Bmc Struct.Biol., 7, 2007
3EVS
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BU of 3evs by Molmil
Crystal structure of the GDF-5:BMP receptor IB complex.
Descriptor: Bone morphogenetic protein receptor type-1B, Growth/differentiation factor 5
Authors:Kotzsch, A, Mueller, T.D.
Deposit date:2008-10-13
Release date:2009-03-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity.
Embo J., 28, 2009
2K3G
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BU of 2k3g by Molmil
NMR structure analysis of a BMP receptor
Descriptor: Bone morphogenetic protein receptor type-1A
Authors:Klages, J, Kotzsch, A, Mueller, T, Kessler, H.
Deposit date:2008-05-07
Release date:2008-12-16
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:The solution structure of BMPR-IA reveals a local disorder-to-order transition upon BMP-2 binding.
Biochemistry, 47, 2008
3B5K
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BU of 3b5k by Molmil
Crystal structure of murine interleukin-5
Descriptor: Interleukin-5
Authors:Mueller, T.D, Patino, E.
Deposit date:2007-10-26
Release date:2008-11-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of murine interleukin-5
To be Published
6H41
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BU of 6h41 by Molmil
Structure of the complex of the IL-5 inhibitory peptide AF17121 bound to the IL-5 receptor IL-5Ralpha
Descriptor: Interleukin-5 receptor subunit alpha, VAL-ASP-GLU-CYS-TRP-ARG-ILE-ILE-ALA-SER-HIS-THR-TRP-PHE-CYS-ALA-GLU-GLU
Authors:Mueller, T.D, Scheide, J.P.
Deposit date:2018-07-20
Release date:2018-12-26
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121.
J. Mol. Biol., 431, 2019
1HZI
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BU of 1hzi by Molmil
INTERLEUKIN-4 MUTANT E9A
Descriptor: INTERLEUKIN-4, SULFATE ION
Authors:Hulsmeyer, M, Scheufler, C, Dreyer, M.K.
Deposit date:2001-01-25
Release date:2001-08-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of interleukin 4 mutant E9A suggests polar steering in receptor-complex formation.
Acta Crystallogr.,Sect.D, 57, 2001
2QJ9
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BU of 2qj9 by Molmil
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B1
Descriptor: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
Authors:Kotzsch, A, Mueller, T.D.
Deposit date:2007-07-06
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QJA
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BU of 2qja by Molmil
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B12
Descriptor: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
Authors:Kotzsch, A, Mueller, T.D.
Deposit date:2007-07-06
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QJB
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BU of 2qjb by Molmil
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant IA/IB
Descriptor: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA, CHLORIDE ION
Authors:Kotzsch, A, Mueller, T.D.
Deposit date:2007-07-06
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2H62
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BU of 2h62 by Molmil
Crystal structure of a ternary ligand-receptor complex of BMP-2
Descriptor: Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
Authors:Mueller, T.D.
Deposit date:2006-05-30
Release date:2007-04-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
Bmc Struct.Biol., 7, 2007
1HIK
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BU of 1hik by Molmil
INTERLEUKIN-4 (WILD-TYPE)
Descriptor: INTERLEUKIN-4
Authors:Mueller, T, Buehner, M.
Deposit date:1995-06-01
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
J.Mol.Biol., 247, 1995
1HIJ
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BU of 1hij by Molmil
INTERLEUKIN-4 MUTANT WITH ARG 88 REPLACED WITH GLN (R88Q)
Descriptor: INTERLEUKIN-4
Authors:Mueller, T, Buehner, M.
Deposit date:1995-06-01
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
J.Mol.Biol., 247, 1995
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219869

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