6QRJ
 
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6QRL
 | | Crystal structure of ShkA _Rec1 in complex with c-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Hybrid kinase, SULFATE ION | | 著者 | Dubey, B.N, Schirmer, T. | | 登録日 | 2019-02-19 | | 公開日 | 2020-01-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Hybrid histidine kinase activation by cyclic di-GMP-mediated domain liberation.
Proc.Natl.Acad.Sci.USA, 117, 2020
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2OAT
 | | ORNITHINE AMINOTRANSFERASE COMPLEXED WITH 5-FLUOROMETHYLORNITHINE | | 分子名称: | 1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE, ORNITHINE AMINOTRANSFERASE | | 著者 | Storici, P, Schirmer, T. | | 登録日 | 1998-05-07 | | 公開日 | 1998-12-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine.
J.Mol.Biol., 285, 1999
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6ZXC
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6ZXB
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6ZXM
 | | Diguanylate cyclase DgcR in complex with c-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Putative GGDEF/response regulator receiver domain protein | | 著者 | Teixeira, R.D, Schirmer, T. | | 登録日 | 2020-07-29 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase.
Nat Commun, 12, 2021
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2YGU
 | | Crystal structure of fire ant venom allergen, Sol I 2 | | 分子名称: | HEPTANE, VENOM ALLERGEN 2 | | 著者 | Borer, A.S, Wassmann, P, Schirmer, T, Markovic-Housley, Z. | | 登録日 | 2011-04-20 | | 公開日 | 2011-11-23 | | 最終更新日 | 2012-02-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of Sol I 2, a Major Allergen from Fire Ant Venom
J.Mol.Biol., 415, 2012
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4KIE
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5IDM
 | | Bifunctional histidine kinase CckA (domain, CA) in complex with c-di-GMP and AMPPNP/Mg2+ | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Cell cycle histidine kinase CckA, MAGNESIUM ION, ... | | 著者 | Dubey, B.N, Schirmer, T. | | 登録日 | 2016-02-24 | | 公開日 | 2016-10-05 | | 最終更新日 | 2022-09-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking.
Sci Adv, 2, 2016
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4LJ3
 | | Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with substrate c-di-GMP and Ca++ | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Cyclic di-GMP phosphodiesterase YahA, ... | | 著者 | Sundriyal, A, Schirmer, T. | | 登録日 | 2013-07-04 | | 公開日 | 2014-01-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Inherent Regulation of EAL Domain-catalyzed Hydrolysis of Second Messenger Cyclic di-GMP.
J.Biol.Chem., 289, 2014
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5JFF
 | | E. coli EcFicT mutant G55R in complex with EcFicA | | 分子名称: | CHLORIDE ION, Probable adenosine monophosphate-protein transferase fic, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, ... | | 著者 | Stanger, F.V, Schirmer, T. | | 登録日 | 2016-04-19 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin.
Plos One, 11, 2016
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5JFZ
 | | E. coli EcFicT in complex with EcFicA mutant E28G | | 分子名称: | Probable adenosine monophosphate-protein transferase fic, Uncharacterized protein YhfG | | 著者 | Stanger, F.V, Schirmer, T. | | 登録日 | 2016-04-19 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin.
Plos One, 11, 2016
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4LYK
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1W25
 | | Response regulator PleD in complex with c-diGMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, STALKED-CELL DIFFERENTIATION CONTROLLING PROTEIN, ... | | 著者 | Chan, C, Schirmer, T, Jenal, U. | | 登録日 | 2004-06-28 | | 公開日 | 2004-11-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Basis of Activity and Allosteric Control of Diguanylate Cyclase
Proc.Natl.Acad.Sci.USA, 101, 2004
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3PYK
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4XJY
 | | Periplasmic repressor protein YfiR | | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, L(+)-TARTARIC ACID, YfiR | | 著者 | Kauer, S, Schirmer, T. | | 登録日 | 2015-01-09 | | 公開日 | 2016-01-20 | | 最終更新日 | 2017-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Periplasmic repressor protein YfiR at 1.8 Angstroms resolution
To Be Published
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2WPU
 | | Chaperoned ruthenium metallodrugs that recognize telomeric DNA | | 分子名称: | (3AS,4S,6AR)-4-(5-((3R,4R)-3,4-DIAMINOPYRROLIDIN-1-YL)-5-OXOPENTYL)TETRAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-2(3H)-ONE-P-CYMENE-CHLORO-RUTHENIUM(III), GLYCEROL, STREPTAVIDIN, ... | | 著者 | Heinisch, T, Schirmer, T, Zimbron, J.M, Sardo, A, Wohlschlager, T, Gradinaru, J, Creus, M, Ward, T.R. | | 登録日 | 2009-08-10 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Chemo-Genetic Optimization of DNA Recognition by Metallodrugs Using a Presenter-Protein Strategy.
Chemistry, 16, 2010
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1MPQ
 | | MALTOPORIN TREHALOSE COMPLEX | | 分子名称: | MALTOPORIN, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | | 著者 | Dutzler, R, Schirmer, T. | | 登録日 | 1997-03-24 | | 公開日 | 1998-03-25 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Channel specificity: structural basis for sugar discrimination and differential flux rates in maltoporin.
J.Mol.Biol., 272, 1997
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4GJV
 | | Streptavidin-S112H | | 分子名称: | CHLORIDE ION, Rhodium, Streptavidin, ... | | 著者 | Heinisch, T, Schirmer, T. | | 登録日 | 2012-08-10 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A dual anchoring strategy for the localization and activation of artificial metalloenzymes based on the biotin-streptavidin technology.
J.Am.Chem.Soc., 135, 2013
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4GJS
 | | Streptavidin-K121H | | 分子名称: | Rhodium, Streptavidin, trichloro{(1,2,3,4,5-eta)-1,2,3,4-tetramethyl-5-[2-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethyl]cyclopentadienyl}rhodium(1+) | | 著者 | Heinisch, T, Schirmer, T. | | 登録日 | 2012-08-10 | | 公開日 | 2013-02-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A dual anchoring strategy for the localization and activation of artificial metalloenzymes based on the biotin-streptavidin technology.
J.Am.Chem.Soc., 135, 2013
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1OPF
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3ZP9
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2JK8
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4PGL
 | | Crystal structure of engineered D-tagatose 3-epimerase PcDTE-ILS6 | | 分子名称: | D-tagatose 3-epimerase, L-sorbose, L-tagatose, ... | | 著者 | Hee, C.S, Bosshart, A, Schirmer, T. | | 登録日 | 2014-05-02 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Directed Divergent Evolution of a Thermostable D-Tagatose Epimerase towards Improved Activity for Two Hexose Substrates.
Chembiochem, 16, 2015
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4PRX
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