6F5H
 
 | | Crystal structure of USP7 in complex with a 4-hydroxypiperidine based inhibitor | | 分子名称: | 3-[[4-oxidanyl-1-[(3~{R})-3-phenylbutanoyl]piperidin-4-yl]methyl]-6-(2-pyrrolidin-1-ylethylamino)pyrimidin-4-one, GLYCEROL, SULFATE ION, ... | | 著者 | Harrison, T, Gavory, G, O'Dowd, C, Helm, M, Flasz, J, Dossang, A, Hughes, C, Cassidy, E, McClelland, K, Odrzywol, E, Page, N, Barker, O, Miel, H, Feutron-Burton, S, Rountree, J.S.S. | | 登録日 | 2017-12-01 | | 公開日 | 2018-04-11 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.
ACS Med Chem Lett, 9, 2018
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8Q61
 | | Co-crystal structure of human AKT2 with compound 3 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-[4-(1-azanyl-3-methyl-3-oxidanyl-cyclobutyl)phenyl]-7-phenyl-1-propyl-pyrido[2,3-b][1,4]oxazin-2-one, GLYCEROL, ... | | 著者 | Harrison, T, Barker, O. | | 登録日 | 2023-08-10 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development.
Sci Rep, 12, 2022
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