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6Z6B
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BU of 6z6b by Molmil
Structure of full-length La Crosse virus L protein (polymerase)
分子名称: RNA (5'-R(*GP*CP*UP*AP*CP*UP*AP*A)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*GP*UP*GP*C)-3'), RNA (5'-R(P*UP*UP*AP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), ...
著者Cusack, S, Gerlach, P, Reguera, J.
登録日2020-05-28
公開日2020-07-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.961 Å)
主引用文献Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
6Z6G
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BU of 6z6g by Molmil
Cryo-EM structure of La Crosse virus polymerase at pre-initiation stage
分子名称: 3'vRNA 1-16, 5'vRNA 1-10, 5'vRNA 9-16, ...
著者Arragain, B, Effantin, G, Gerlach, P, Reguera, J, Schoehn, G, Cusack, S, Malet, H.
登録日2020-05-28
公開日2020-07-29
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
5LG6
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BU of 5lg6 by Molmil
Structure of the deglycosylated porcine aminopeptidase N ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ZINC ION
著者Santiago, C, Reguera, J, Mudgal, G, Casasnovas, J.M.
登録日2016-07-06
公開日2017-04-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.
Sci Rep, 7, 2017
5LDS
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BU of 5lds by Molmil
Structure of the porcine aminopeptidase N ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Santiago, C, Reguera, J, Mudgal, G, Casasnovas, J.M.
登録日2016-06-27
公開日2017-04-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.
Sci Rep, 7, 2017
5MUS
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BU of 5mus by Molmil
Structure of the C-terminal domain of a reptarenavirus L protein
分子名称: CHLORIDE ION, GLYCEROL, L protein
著者Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S.
登録日2017-01-14
公開日2017-05-17
最終更新日2017-05-24
実験手法X-RAY DIFFRACTION (2.009 Å)
主引用文献Structural insights into reptarenavirus cap-snatching machinery.
PLoS Pathog., 13, 2017
5MUY
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BU of 5muy by Molmil
Structure of a C-terminal domain of a reptarenavirus L protein with m7GTP
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, L protein
著者Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S.
登録日2017-01-14
公開日2017-05-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural insights into reptarenavirus cap-snatching machinery.
PLoS Pathog., 13, 2017
5MV0
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BU of 5mv0 by Molmil
Structure of an N-terminal domain of a reptarenavirus L protein
分子名称: L protein, PHOSPHATE ION
著者Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S.
登録日2017-01-14
公開日2017-05-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural insights into reptarenavirus cap-snatching machinery.
PLoS Pathog., 13, 2017
5MUZ
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BU of 5muz by Molmil
Structure of a C-terminal domain of a reptarenavirus L protein
分子名称: L protein
著者Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S.
登録日2017-01-14
公開日2017-05-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.776 Å)
主引用文献Structural insights into reptarenavirus cap-snatching machinery.
PLoS Pathog., 13, 2017
7Z0H
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BU of 7z0h by Molmil
Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.6 A (focus subunit AC40).
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Nguyen, P.Q, Huecas, S, Plaza-Pegueroles, A, Fernandez-Tornero, C.
登録日2022-02-22
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
7Z2Z
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BU of 7z2z by Molmil
Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A
分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
著者Nguyen, P.Q, Fernandez-Tornero, C.
登録日2022-03-01
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
7Z30
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BU of 7z30 by Molmil
Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.9 A (focus subunit C11 terminal Zn-ribbon in the funnel pore).
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Nguyen, P.Q, Fernandez-Tornero, C.
登録日2022-03-01
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
7Z31
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BU of 7z31 by Molmil
Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore).
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Nguyen, P.Q, Huecas, S, Plaza-Pegueroles, A, Fernandez-Tornero, C.
登録日2022-03-01
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
8BWS
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BU of 8bws by Molmil
Structure of yeast RNA Polymerase III elongation complex at 3.3 A
分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
著者Nguyen, P.Q, Fernandez-Tornero, C.
登録日2022-12-07
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
6Z8K
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BU of 6z8k by Molmil
La Crosse virus polymerase at elongation mimicking stage
分子名称: La Crosse virus 3' vRNA (1-16), La Crosse virus 5' vRNA (9-16), La Crosse virus 5' vRNA 1-10, ...
著者Arragain, B, Effantin, G, Schoehn, G, Cusack, S, Malet, H.
登録日2020-06-02
公開日2020-07-29
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
5LHD
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BU of 5lhd by Molmil
Structure of glycosylated human aminopeptidase N
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Recacha, R, Mudgal, G, Santiago, C, Casasnovas, J.M.
登録日2016-07-11
公開日2017-04-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.
Sci Rep, 7, 2017
8C4T
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BU of 8c4t by Molmil
Hantaan virus polymerase bound to its 5' viral RNA
分子名称: MAGNESIUM ION, RNA (5'-R(P*UP*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*A)-3'), RNA-directed RNA polymerase L
著者Durieux trouilleton, Q, Arragain, B, Malet, H.
登録日2023-01-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
8C4U
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BU of 8c4u by Molmil
Hantaan virus polymerase in replication pre-initiation state
分子名称: MAGNESIUM ION, RNA (5'-R(P*UP*AP*GP*GP*AP*GP*UP*AP*UP*CP*CP*AP*CP*CP*GP*CP*AP*AP*GP*A)-3'), RNA (5'-R(P*UP*UP*UP*UP*GP*CP*GP*GP*AP*GP*UP*AP*CP*UP*AP*CP*UP*A)-3'), ...
著者Durieux trouilleton, Q, Arragain, B, Malet, H.
登録日2023-01-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
8C4S
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BU of 8c4s by Molmil
Apo Hantaan virus polymerase core
分子名称: RNA-directed RNA polymerase L
著者Durieux trouilleton, Q, Arragain, B, Malet, H.
登録日2023-01-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
8C4V
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BU of 8c4v by Molmil
Hantaan virus polymerase in replication elongation state
分子名称: MAGNESIUM ION, RNA (5'-R(P*AP*CP*UP*AP*CP*UP*A)-3'), RNA (5'-R(P*AP*GP*GP*AP*GP*UP*AP*UP*CP*CP*AP*CP*CP*GP*CP*AP*AP*GP*A)-3'), ...
著者Durieux trouilleton, Q, Arragain, B, Malet, H.
登録日2023-01-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
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