1SUH
 
 | | AMINO-TERMINAL DOMAIN OF EPITHELIAL CADHERIN IN THE CALCIUM BOUND STATE, NMR, 20 STRUCTURES | | 分子名称: | EPITHELIAL CADHERIN | | 著者 | Overduin, M, Tong, K.I, Kay, C.M, Ikura, M. | | 登録日 | 1996-01-30 | | 公開日 | 1996-07-11 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 1H, 15N and 13C resonance assignments and monomeric structure of the amino-terminal extracellular domain of epithelial cadherin.
J.Biomol.NMR, 7, 1996
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1AB2
 | | THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY 2 DOMAIN OF C-ABL | | 分子名称: | C-ABL TYROSINE KINASE SH2 DOMAIN | | 著者 | Overduin, M, Rios, C.B, Mayer, B.J, Baltimore, D, Cowburn, D. | | 登録日 | 1993-07-19 | | 公開日 | 1994-01-31 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of the src homology 2 domain of c-abl.
Cell(Cambridge,Mass.), 70, 1992
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2HBP
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4QMD
 | | Crystal structure of human envoplakin plakin repeat domain | | 分子名称: | Envoplakin | | 著者 | Mohammed, F, Al-Jassar, C, White, S.A, Fogl, C, Jeeves, M, Knowles, T.J, Odinstova, E, Rodriguez-Zamora, P, Overduin, M, Chidgey, M. | | 登録日 | 2014-06-16 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin.
Nat Commun, 7, 2016
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7A2D
 | | Structure-function analyses of dual-BON domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation to the cell division site | | 分子名称: | Uncharacterized protein YraP | | 著者 | Bryant, J.A, Morris, F.C, Knowles, T.J, Maderbocus, R, Heinz, E, Boelter, G, Alodaini, D, Colyer, A, Wotherspoon, P.J, Staunton, K.A, Jeeves, M, Browning, D.F, Sevastsyanovich, Y.R, Wells, T.J, Rossiter, A.E, Bavro, V.N, Sridhar, P, Ward, D.G, Chong, Z.S, Goodall, E.C.A, Icke, C, Teo, A, Chng, S.S, Roper, D.I, Lithgow, T, Cunningham, A.F, Banzhaf, M, Overduin, M, Henderson, I.R. | | 登録日 | 2020-08-17 | | 公開日 | 2020-12-30 | | 最終更新日 | 2021-02-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of dual BON-domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation.
Elife, 9, 2020
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2V9H
 | | Solution Structure of an Escherichia coli YaeT tandem POTRA domain | | 分子名称: | OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR YAET | | 著者 | Knowles, T.J, Jeeves, M, Bobat, S, Dancea, F, Mcclelland, D.M, Palmer, T, Overduin, M, Henderson, I.R. | | 登録日 | 2007-08-23 | | 公開日 | 2008-05-06 | | 最終更新日 | 2020-01-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Fold and Function of Polypeptide Transport-Associated Domains Responsible for Delivering Unfolded Proteins to Membranes.
Mol.Microbiol., 68, 2008
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1C07
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1J9I
 | | STRUCTURE OF THE DNA BINDING DOMAIN OF THE GPNU1 SUBUNIT OF LAMBDA TERMINASE | | 分子名称: | TERMINASE SMALL SUBUNIT | | 著者 | De Beer, T, Meyer, J, Ortega, M, Yang, Q, Maes, L, Duffy, C, Berton, N, Sippy, J, Overduin, M, Feiss, M, Catalano, C. | | 登録日 | 2001-05-25 | | 公開日 | 2002-08-14 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into specific DNA recognition during the assembly of a viral genome packaging machine.
Mol.Cell, 9, 2002
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2KCJ
 | | solution structure of FAPP1 PH domain | | 分子名称: | Pleckstrin homology domain-containing family A member 3 | | 著者 | Lenoir, M, Coskun, U, James, J, Simons, K, Overduin, M. | | 登録日 | 2008-12-22 | | 公開日 | 2009-12-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domains.
Embo Rep., 11, 2010
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1EDH
 | | E-CADHERIN DOMAINS 1 AND 2 IN COMPLEX WITH CALCIUM | | 分子名称: | CALCIUM ION, E-CADHERIN, MERCURY (II) ION | | 著者 | Nagar, B, Overduin, M, Ikura, M, Rini, J.M. | | 登録日 | 1996-05-15 | | 公開日 | 1997-01-11 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of calcium-induced E-cadherin rigidification and dimerization.
Nature, 380, 1996
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1FF1
 | | STRUCTURE OF THE SECOND EPS15 HOMOLOGY DOMAIN OF HUMAN EPS15 IN COMPLEX WITH PTGSSSTNPFL | | 分子名称: | CALCIUM ION, EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15, PTGSSSTNPFL PEPTIDE | | 著者 | De Beer, T, Hoofnagle, A.N, Enmon, J.L, Bowers, R.C, Yamabhai, M, Kay, B.K, Overduin, M. | | 登録日 | 2000-07-24 | | 公開日 | 2000-11-01 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular mechanism of NPF recognition by EH domains.
Nat.Struct.Biol., 7, 2000
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1F8H
 | | STRUCTURE OF THE SECOND EPS15 HOMOLOGY DOMAIN OF HUMAN EPS15 IN COMPLEX WITH PTGSSSTNPFR | | 分子名称: | CALCIUM ION, EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15, PTGSSSTNPFR | | 著者 | De Beer, T, Hoofnagle, A.N, Enmon, J.L, Bowers, R.C, Yamabhai, M, Kay, B.K, Overduin, M. | | 登録日 | 2000-06-30 | | 公開日 | 2000-11-01 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular mechanism of NPF recognition by EH domains.
Nat.Struct.Biol., 7, 2000
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2LG1
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2KM7
 | | Solution Structure of BamE, a component of the outer membrane protein assembly machinery in Escherichia coli | | 分子名称: | Small protein A | | 著者 | Knowles, T.J, Sridhar, P, Rajesh, S, Manoli, E, Henderson, I.R, Overduin, M. | | 登録日 | 2009-07-24 | | 公開日 | 2011-02-02 | | 最終更新日 | 2021-10-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and function of BamE within the outer membrane and the beta-barrel assembly machine.
Embo Rep., 12, 2011
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1HYJ
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1HYI
 | | SOLUTION STRUCTURE OF THE EEA1 FYVE DOMAIN COMPLEXED WITH INOSITOL 1,3-BISPHOSPHATE | | 分子名称: | ENDOSOME-ASSOCIATED PROTEIN, PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTER, ZINC ION | | 著者 | Kutateladze, T, Overduin, M. | | 登録日 | 2001-01-19 | | 公開日 | 2001-03-14 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural mechanism of endosome docking by the FYVE domain.
Science, 291, 2001
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1EH2
 | | STRUCTURE OF THE SECOND EPS15 HOMOLOGY DOMAIN OF HUMAN EPS15, NMR, 20 STRUCTURES | | 分子名称: | CALCIUM ION, EPS15 | | 著者 | De Beer, T, Carter, R.E, Lobel-Rice, K.E, Sorkin, A, Overduin, M. | | 登録日 | 1998-07-10 | | 公開日 | 1999-07-22 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Asn-Pro-Phe binding pocket of the Eps15 homology domain.
Science, 281, 1998
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2MLS
 | | Membrane Bilayer complex with Matrix Metalloproteinase-12 at its Beta-face | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Macrophage metalloelastase, ... | | 著者 | Koppisetti, R.K, Fulcher, Y.G, Prior, S.H, Lenoir, M, Overduin, M, Van Doren, S.R. | | 登録日 | 2014-03-04 | | 公開日 | 2014-12-03 | | 最終更新日 | 2014-12-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ambidextrous binding of cell and membrane bilayers by soluble matrix metalloproteinase-12.
Nat Commun, 5, 2014
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2MDX
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2MLR
 | | Membrane Bilayer complex with Matrix Metalloproteinase-12 at its Alpha-face | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Macrophage metalloelastase, ... | | 著者 | Koppisetti, R.K, Fulcher, Y.G, Prior, S.H, Lenoir, M, Overduin, M, Van Doren, S.R. | | 登録日 | 2014-03-04 | | 公開日 | 2014-12-03 | | 最終更新日 | 2014-12-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ambidextrous binding of cell and membrane bilayers by soluble matrix metalloproteinase-12.
Nat Commun, 5, 2014
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2N4I
 | | The solution structure of Skint-1, a critical determinant of dendritic epidermal gamma-delta T cell selection | | 分子名称: | Selection and upkeep of intraepithelial T-cells protein 1 | | 著者 | Salim, M, Knowles, T.J, Hart, R, Mohammed, F, Woodward, M.J, Willcox, C.R, Overduin, M, Hayday, A.C, Willcox, B.E. | | 登録日 | 2015-06-18 | | 公開日 | 2016-03-02 | | 最終更新日 | 2016-05-11 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Characterization of a Putative Receptor Binding Surface on Skint-1, a Critical Determinant of Dendritic Epidermal T Cell Selection.
J.Biol.Chem., 291, 2016
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1AWO
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3RCP
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6T28
 | | Crystal structure of human calmodulin-dependent protein kinase 1D (CAMK1D) bound to compound 19 (CS640) | | 分子名称: | 1,2-ETHANEDIOL, 2-[(3~{S})-3-azanylpiperidin-1-yl]-4-[[2,6-di(propan-2-yl)pyridin-4-yl]amino]pyrimidine-5-carboxamide, Calcium/calmodulin-dependent protein kinase type 1D, ... | | 著者 | Kraemer, A, Sorrell, F, Butterworth, S, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2019-10-08 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesityin VivoMouse Model.
J.Med.Chem., 63, 2020
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6T29
 | | Crystal structure of human calmodulin-dependent protein kinase 1D (CAMK1D) bound to compound 18 (CS587) | | 分子名称: | 1,2-ETHANEDIOL, 2-[(3~{S})-3-azanylpiperidin-1-yl]-4-[[3,5-bis(2-cyanopropan-2-yl)phenyl]amino]pyrimidine-5-carboxamide, Calcium/calmodulin-dependent protein kinase type 1D, ... | | 著者 | Kraemer, A, Sorrell, F, Butterworth, S, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2019-10-08 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.484 Å) | | 主引用文献 | Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesityin VivoMouse Model.
J.Med.Chem., 63, 2020
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