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2XG6
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BU of 2xg6 by Molmil
Molecular insights into clinically isolated OmpC mutants and their role in multi-drug resistance
分子名称: OMPC, SULFATE ION
著者Lou, H, Naismith, J.H.
登録日2010-05-31
公開日2010-07-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.47 Å)
主引用文献Altered Antibiotic Transport in Ompc Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. Coli.
Plos One, 6, 2011
2XE2
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BU of 2xe2 by Molmil
Molecular insights into clinically isolated OmpC20 mutants and their role in multi-drug resistance
分子名称: N-OCTYL-2-HYDROXYETHYL SULFOXIDE, OUTER MEMBRANE PORIN C
著者Bamford, V.A, Naismith, J.H.
登録日2010-05-10
公開日2010-05-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Altered Antibiotic Transport in Ompc Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. Coli.
Plos One, 6, 2011
2XU2
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BU of 2xu2 by Molmil
Crystal Structure of the hypothetical protein PA4511 from Pseudomonas aeruginosa
分子名称: CITRIC ACID, UPF0271 PROTEIN PA4511
著者Oke, M, Carter, L.G, Johnson, K.A, Liu, H, McMahon, S.A, White, M.F, Naismith, J.H.
登録日2010-10-14
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
2XE1
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BU of 2xe1 by Molmil
Molecular insights into clinically isolated OmpC mutants and their role in multi-drug resistance
分子名称: DECANE, HEXANE, OUTER MEMBRANE PROTEIN C
著者Bamford, V.A, Naismith, J.H.
登録日2010-05-10
公開日2010-05-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Altered Antibiotic Transport in Ompc Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. Coli.
Plos One, 6, 2011
2XBN
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BU of 2xbn by Molmil
Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, MAGNESIUM ION, SERINE PALMITOYLTRANSFERASE
著者Lowther, J, Yard, B.A, Johnson, K.A, Carter, L.G, Bhat, V.T, Raman, M.C.C, Clarke, D.J, Ramakers, B, McMahon, S.A, Naismith, J.H, Campopiano, D.J.
登録日2010-04-13
公開日2010-05-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Inhibition of the Plp-Dependent Enzyme Serine Palmitoyltransferase by Cycloserine: Evidence for a Novel Decarboxylative Mechanism of Inactivation.
Mol.Biosystems, 6, 2010
2YNK
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BU of 2ynk by Molmil
Wzi, an Outer Membrane Protein Involved in Group 1 Capsule Assembly in Escherichia coli, is a Carbohydrate Binding Beta-Barrel
分子名称: DODECANE, HEXANE, N-OCTANE, ...
著者Bushell, S.R, Mainprize, I.L, Wear, M.A, Lou, H, Kong, L, Davis, B, Bayley, H, Whitfield, C, Naismith, J.H.
登録日2012-10-16
公開日2013-05-15
最終更新日2013-05-29
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Wzi is an Outer Membrane Lectin that Underpins Group 1 Capsule Assembly in Escherichia Coli.
Structure, 21, 2013
2WJ9
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BU of 2wj9 by Molmil
ArdB
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Weikart, N.D, Roberts, G, Johnson, K.A, Oke, M, Cooper, L.P, McMahon, S.A, White, J.H, Liu, H, Carter, L.G, Walkinshaw, M.D, Blakely, G.W, Naismith, J.H, Dryden, D.T.F.
登録日2009-05-25
公開日2010-08-18
最終更新日2018-05-02
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
3ZXY
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BU of 3zxy by Molmil
Structure of S218A mutant of the protease domain of PatA
分子名称: SUBTILISIN-LIKE PROTEIN
著者Koehnke, J, Zollman, D, Vendome, J, Raab, A, Houssen, W.E, Smith, M.C, Jaspars, M, Naismith, J.H.
登録日2011-08-16
公開日2012-08-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献The Discovery of New Cyanobactins from Cyanothece Pcc 7425 Defines a New Signature for Processing of Patellamides.
Chembiochem, 13, 2012
3ZXX
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BU of 3zxx by Molmil
Structure of self-cleaved protease domain of PatA
分子名称: SUBTILISIN-LIKE PROTEIN
著者Koehnke, J, Zollman, D, Vendome, J, Raab, A, Houssen, W.E, Smith, M.C, Jaspars, M, Naismith, J.H.
登録日2011-08-16
公開日2012-08-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Discovery of New Cyanobactins from Cyanothece Pcc 7425 Defines a New Signature for Processing of Patellamides.
Chembiochem, 13, 2012
3ZFV
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BU of 3zfv by Molmil
Crystal structure of an archaeal CRISPR-associated Cas6 nuclease
分子名称: CRISPR-ASSOCIATED ENDORIBONUCLEASE CAS6 1, GLYCEROL
著者Reeks, J, Liu, H, White, M.F, Naismith, J.H.
登録日2012-12-12
公開日2013-04-03
最終更新日2013-05-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of a Dimeric Crenarchaeal Cas6 Enzyme with an Atypical Active Site for Crispr RNA Processing
Biochem.J., 452, 2013
3ZC4
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BU of 3zc4 by Molmil
The structure of Csa5 from Sulfolobus solfataricus.
分子名称: DI(HYDROXYETHYL)ETHER, SSO1398
著者Reeks, J, Anderson, L, White, M.F, Naismith, J.H.
登録日2012-11-15
公開日2013-02-20
最終更新日2013-07-31
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structure of the Archaeal Cascade Subunit Csa5: Relating the Small Subunits of Crispr Effector Complexes.
RNA Biol., 10, 2013
3ZLK
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BU of 3zlk by Molmil
Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
分子名称: CHLORIDE ION, GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, N-(6-AMINO-1-BENZYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL)BENZENESULFONAMIDE
著者Alphey, M.S, Pirrie, L, Torrie, L.S, Gardiner, M, Sarkar, A, Brenk, R, Westwood, N.J, Gray, D, Naismith, J.H.
登録日2013-02-01
公開日2013-02-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa.
ACS Chem. Biol., 8, 2013
3ZLL
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BU of 3zll by Molmil
Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-azanyl-6-oxidanyl-1-(phenylmethyl)pyrimidine-2,4-dione, CHLORIDE ION, ...
著者Alphey, M.S, Pirrie, L, Torrie, L.S, Gardiner, M, Sarkar, A, Brenk, R, Westwood, N.J, Gray, D, Naismith, J.H.
登録日2013-02-01
公開日2013-02-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa.
ACS Chem. Biol., 8, 2013
4AGE
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BU of 4age by Molmil
MTSSL spin labeled D67C mutant of MscS in the open form
分子名称: SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL
著者Pliotas, C, Brannigan, E, Naismith, J.H.
登録日2012-01-26
公開日2012-08-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4.84 Å)
主引用文献Conformational State of the Mscs Mechanosensitive Channel in Solution Revealed by Pulsed Electron-Electron Double Resonance (Peldor) Spectroscopy.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AGF
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BU of 4agf by Molmil
MTSSL spin labeled L124C mutant of MscS in the open form
分子名称: SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL
著者Pliotas, C, Brannigan, E, Naismith, J.H.
登録日2012-01-26
公開日2012-08-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4.7 Å)
主引用文献Conformational State of the Mscs Mechanosensitive Channel in Solution Revealed by Pulsed Electron-Electron Double Resonance (Peldor) Spectroscopy.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AKS
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BU of 4aks by Molmil
PatG macrocyclase domain
分子名称: THIAZOLINE OXIDASE/SUBTILISIN-LIKE PROTEASE
著者Koehnke, J, Bent, A, Houssen, W.E, Zollman, D, Morawitz, F, Shirran, S, Vendome, J, Nneoyiegbe, A.F, Trembleau, L, Botting, C.H, Smith, M.C.M, Jaspars, M, Naismith, J.H.
登録日2012-02-28
公開日2012-07-18
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The Mechanism of Patellamide Macrocyclization Revealed by the Characterization of the Patg Macrocyclase Domain.
Nat.Struct.Mol.Biol., 19, 2012
4AKT
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BU of 4akt by Molmil
PatG macrocyclase in complex with peptide
分子名称: SUBSTRATE ANALOGUE, THIAZOLINE OXIDASE/SUBTILISIN-LIKE PROTEASE
著者Koehnke, J, Bent, A, Houssen, W.E, Zollman, D, Morawitz, F, Shirran, S, Vendome, J, Nneoyiegbe, A.F, Trembleau, L, Botting, C.H, Smith, M.C.M, Jaspars, M, Naismith, J.H.
登録日2012-02-28
公開日2012-07-18
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献The Mechanism of Patellamide Macrocyclization Revealed by the Characterization of the Patg Macrocyclase Domain.
Nat.Struct.Mol.Biol., 19, 2012
4AP4
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BU of 4ap4 by Molmil
Rnf4 - ubch5a - ubiquitin heterotrimeric complex
分子名称: E3 UBIQUITIN LIGASE RNF4, UBIQUITIN C, UBIQUITIN-CONJUGATING ENZYME E2 D1, ...
著者Plechanovova, A, Hay, R.T, Tatham, M.H, Jaffray, E, Naismith, J.H.
登録日2012-03-30
公開日2012-07-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structure of a Ring E3 Ligase and Ubiquitin-Loaded E2 Primed for Catalysis
Nature, 489, 2012
4AAY
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BU of 4aay by Molmil
Crystal Structure of the arsenite oxidase protein complex from Rhizobium species strain NT-26
分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, AROA, AROB, ...
著者Oke, M, Santini, J.M, Naismith, J.H.
登録日2011-12-05
公開日2012-12-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Respiratory Arsenite Oxidase: Structure and the Role of Residues Surrounding the Rieske Cluster.
Plos One, 8, 2013
4AI5
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BU of 4ai5 by Molmil
Crystal structure of Y16F of 3-methyladenine DNA glycosylase I (TAG) in complex with 3-methyladenine
分子名称: 3-METHYL-3H-PURIN-6-YLAMINE, DNA-3-METHYLADENINE GLYCOSYLASE I, SULFATE ION, ...
著者Zhu, X, Naismith, J.H.
登録日2012-02-08
公開日2012-02-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献A Model for 3-Methyladenine Recognition by 3-Methyladenine DNA Glycosylase I (Tag) from Staphylococcus Aureus.
Acta Crystallogr.,Sect.F, 68, 2012
4AIA
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BU of 4aia by Molmil
The structural basis of 3-methyladenine recognition by 3- methyladenine DNA glycosylase I (TAG) from Staphylococcus aureus
分子名称: 3-METHYL-3H-PURIN-6-YLAMINE, DNA-3-METHYLADENINE GLYCOSYLASE I, SULFATE ION, ...
著者Yan, X, Naismith, J.H.
登録日2012-02-08
公開日2012-02-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Model for 3-Methyladenine Recognition by 3-Methyladenine DNA Glycosylase I (Tag) from Staphylococcus Aureus.
Acta Crystallogr.,Sect.F, 68, 2012
4B42
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BU of 4b42 by Molmil
Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, ...
著者Alphey, M.S, Pirrie, L, Torrie, L.S, Gardiner, M, Sarkar, A, Brenk, R, Westwood, N.J, Gray, D, Naismith, J.H.
登録日2012-07-27
公開日2012-10-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.505 Å)
主引用文献Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa.
ACS Chem. Biol., 8, 2013
4B2W
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BU of 4b2w by Molmil
Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, ...
著者Alphey, M.S, Pirrie, L, Torrie, L, Gardiner, M, Westwood, N.J, Gray, D, Naismith, J.H.
登録日2012-07-18
公開日2013-05-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa.
ACS Chem. Biol., 8, 2013
4AVR
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BU of 4avr by Molmil
Crystal structure of the hypothetical protein Pa4485 from Pseudomonas aeruginosa
分子名称: PA4485
著者McMahon, S.A, Moynie, L, Liu, H, Duthie, F, Alphey, M.S, Naismith, J.H.
登録日2012-05-29
公開日2013-01-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery.
Acta Crystallogr.,Sect.F, 69, 2013
4ARW
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BU of 4arw by Molmil
Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, ...
著者Alphey, M.S, Pirrie, L, Torrie, L.S, Gardiner, M, Westwood, N.J, Gray, D, Naismith, J.H.
登録日2012-04-26
公開日2012-10-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa.
ACS Chem. Biol., 8, 2013

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