1QQT
 
 | | METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI | | Descriptor: | METHIONYL-TRNA SYNTHETASE, ZINC ION | | Authors: | Mechulam, Y, Schmitt, E, Maveyraud, L, Zelwer, C, Nureki, O, Yokoyama, S, Konno, M, Blanquet, S. | | Deposit date: | 1999-06-08 | | Release date: | 2000-01-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features.
J.Mol.Biol., 294, 1999
|
|
2QN6
 | | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Translation initiation factor 2 alpha subunit, ... | | Authors: | Mechulam, Y, Yatime, L, Blanquet, S, Schmitt, E. | | Deposit date: | 2007-07-18 | | Release date: | 2007-11-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states.
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
3V11
 | |
1MKH
 | |
4U5M
 | | Structure of a left-handed DNA G-quadruplex | | Descriptor: | DNA (28-MER), MAGNESIUM ION, POTASSIUM ION | | Authors: | Schmitt, E, Mechulam, Y, Phan, A.T, Brahim, H, Chung, W.J, Lim, K.W. | | Deposit date: | 2014-07-25 | | Release date: | 2015-02-25 | | Last modified: | 2015-03-11 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of a left-handed DNA G-quadruplex.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
2FMT
 | | METHIONYL-TRNAFMET FORMYLTRANSFERASE COMPLEXED WITH FORMYL-METHIONYL-TRNAFMET | | Descriptor: | FORMYL-METHIONYL-TRNAFMET2, MAGNESIUM ION, METHIONYL-TRNA FMET FORMYLTRANSFERASE, ... | | Authors: | Schmitt, E, Mechulam, Y, Blanquet, S. | | Deposit date: | 1998-07-29 | | Release date: | 1999-07-29 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of methionyl-tRNAfMet transformylase complexed with the initiator formyl-methionyl-tRNAfMet.
EMBO J., 17, 1998
|
|
6Q6R
 | | Recognition of different base tetrads by RHAU: X-ray crystal structure of G4 recognition motif bound to the 3-end tetrad of a DNA G-quadruplex | | Descriptor: | ATP-dependent DNA/RNA helicase DHX36, POTASSIUM ION, Parallel stranded DNA G-quadruplex | | Authors: | Heddi, B, Cheong, V.V, Schmitt, E, Mechulam, Y, Phan, A.T. | | Deposit date: | 2018-12-11 | | Release date: | 2019-10-16 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex.
J.Struct.Biol., 209, 2020
|
|
6QJO
 | | DNA containing both right- and left-handed parallel-stranded G-quadruplexes | | Descriptor: | DNA (28-MER), POTASSIUM ION | | Authors: | Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Schmitt, E, Mechulam, Y, Phan, A.T. | | Deposit date: | 2019-01-24 | | Release date: | 2019-07-03 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes.
Nucleic Acids Res., 47, 2019
|
|
2QMU
 | | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, Translation initiation factor 2 alpha subunit, ... | | Authors: | Yatime, L, Mechulam, Y, Blanquet, S, Schmitt, E. | | Deposit date: | 2007-07-17 | | Release date: | 2007-11-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states.
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
5OCD
 | |
3M4X
 | |
1RQG
 | | Methionyl-tRNA synthetase from Pyrococcus abyssi | | Descriptor: | Methionyl-tRNA synthetase, ZINC ION | | Authors: | Crepin, T, Schmitt, E, Blanquet, S, Mechulam, Y. | | Deposit date: | 2003-12-05 | | Release date: | 2004-05-25 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Three-dimensional structure of methionyl-tRNA synthetase from Pyrococcus abyssi.
Biochemistry, 43, 2004
|
|
6Y4B
 | |
6EZ3
 | |
6FQ2
 | | Structure of minimal sequence for left -handed G-quadruplex formation | | Descriptor: | DNA (5'-D(*GP*TP*GP*GP*TP*GP*GP*TP*GP*GP*TP*G)-3'), POTASSIUM ION | | Authors: | Schmitt, E, Mechulam, Y, Phan, A.T, Heddi, B, Bakalar, B. | | Deposit date: | 2018-02-13 | | Release date: | 2018-12-05 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew. Chem. Int. Ed. Engl., 58, 2019
|
|
6Y3G
 | | Crystal structure of phenylalanine tRNA from Escherichia coli | | Descriptor: | CALCIUM ION, GLYCEROL, GUANIDINE, ... | | Authors: | Bourgeois, G, Mechulam, Y, Schmitt, E. | | Deposit date: | 2020-02-18 | | Release date: | 2020-12-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates.
Rna, 26, 2020
|
|
8PHV
 | | Structure of Human selenomethionylated Cdc123 bound to domain 3 of eIF2 gamma | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division cycle protein 123 homolog, Eukaryotic translation initiation factor 2 subunit 3 | | Authors: | Schmitt, E, Mechulam, Y, Cardenal Peralta, C, Fagart, J, Seufert, W. | | Deposit date: | 2023-06-20 | | Release date: | 2023-08-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Binding of human Cdc123 to eIF2 gamma.
J.Struct.Biol., 215, 2023
|
|
8PHD
 | | Structure of Human Cdc123 bound to domain 3 of eIF2 gamma and ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division cycle protein 123 homolog, Eukaryotic translation initiation factor 2 subunit 3, ... | | Authors: | Schmitt, E, Mechulam, Y, Cardenal Peralta, C, Fagart, J, Seufert, W. | | Deposit date: | 2023-06-19 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Binding of human Cdc123 to eIF2 gamma.
J.Struct.Biol., 215, 2023
|
|
8BRU
 | | Escherichia coli methionyl-tRNA synthetase mutant L13M,I297C | | Descriptor: | CITRIC ACID, Methionine--tRNA ligase, ZINC ION | | Authors: | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | | Deposit date: | 2022-11-24 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
|
|
8BRV
 | | Escherichia coli methionyl-tRNA synthetase mutant L13M,I297C complexed with beta3-methionine. | | Descriptor: | (3R)-3-amino-5-(methylsulfanyl)pentanoic acid, CITRIC ACID, Methionine--tRNA ligase, ... | | Authors: | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | | Deposit date: | 2022-11-24 | | Release date: | 2023-08-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
|
|
8BRX
 | | Escherichia coli methionyl-tRNA synthetase mutant L13C,I297C complexed with beta-3-methionine | | Descriptor: | (3R)-3-amino-5-(methylsulfanyl)pentanoic acid, CITRIC ACID, Methionine--tRNA ligase, ... | | Authors: | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | | Deposit date: | 2022-11-24 | | Release date: | 2023-08-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
|
|
8BRW
 | | Escherichia coli methionyl-tRNA synthetase mutant L13C,I297C | | Descriptor: | Methionine--tRNA ligase, ZINC ION | | Authors: | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | | Deposit date: | 2022-11-24 | | Release date: | 2023-08-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
|
|
5L4O
 | |
5MLQ
 | | Structure of CDPS from Nocardia brasiliensis | | Descriptor: | CDPS, CITRIC ACID | | Authors: | Bourgeois, G, Seguin, J, Moutiez, M, Babin, M, Belin, P, Mechulam, Y, Gondry, M, Schmitt, E. | | Deposit date: | 2016-12-07 | | Release date: | 2018-05-02 | | Last modified: | 2019-05-15 | | Method: | X-RAY DIFFRACTION (3.18 Å) | | Cite: | Structural basis for partition of the cyclodipeptide synthases into two subfamilies.
J.Struct.Biol., 203, 2018
|
|
1FMT
 | | METHIONYL-TRNAFMET FORMYLTRANSFERASE FROM ESCHERICHIA COLI | | Descriptor: | METHIONYL-TRNA FMET FORMYLTRANSFERASE | | Authors: | Schmitt, E, Mechulam, Y. | | Deposit date: | 1997-10-13 | | Release date: | 1998-01-28 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of crystalline Escherichia coli methionyl-tRNA(f)Met formyltransferase: comparison with glycinamide ribonucleotide formyltransferase.
EMBO J., 15, 1996
|
|
