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180L
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BU of 180l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: LYSOZYME
Authors:Kuroki, R, Weaver, L, Zhang, X.-J, Matthews, B.W.
Deposit date:1995-03-24
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
189L
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BU of 189l by Molmil
ENHANCEMENT OF PROTEIN STABILITY BY THE COMBINATION OF POINT MUTATIONS IN T4 LYSOZYME IS ADDITIVE
Descriptor: T4 LYSOZYME
Authors:Zhang, X.-J, Matthews, B.W.
Deposit date:1995-05-09
Release date:1995-07-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Enhancement of protein stability by the combination of point mutations in T4 lysozyme is additive.
Protein Eng., 8, 1995
157L
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BU of 157l by Molmil
CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Blaber, M, Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
171L
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BU of 171l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Heinz, D, Matthews, B.W.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
150L
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BU of 150l by Molmil
CONSERVATION OF SOLVENT-BINDING SITES IN 10 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Faber, H.R, Matthews, B.W.
Deposit date:1994-01-25
Release date:1994-04-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conservation of solvent-binding sites in 10 crystal forms of T4 lysozyme.
Protein Sci., 3, 1994
175L
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BU of 175l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Baldwin, E, Matthews, B.W.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
159L
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BU of 159l by Molmil
CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Blaber, M, Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
168L
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BU of 168l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Zhang, X.-J, Matthews, B.W.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
169L
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BU of 169l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Zhang, X.-J, Matthews, B.W.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
148L
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BU of 148l by Molmil
A COVALENT ENZYME-SUBSTRATE INTERMEDIATE WITH SACCHARIDE DISTORTION IN A MUTANT T4 LYSOZYME
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, BETA-MERCAPTOETHANOL, SUBSTRATE CLEAVED FROM CELL WALL OF ESCHERICHIA COLI, ...
Authors:Kuroki, R, Weaver, L.H, Matthews, B.W.
Deposit date:1993-10-27
Release date:1994-04-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A covalent enzyme-substrate intermediate with saccharide distortion in a mutant T4 lysozyme.
Science, 262, 1993
165L
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BU of 165l by Molmil
CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Blaber, M, Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
172L
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BU of 172l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:Weaver, L.H, Zhang, X.-J, Matthews, B.W.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
153L
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BU of 153l by Molmil
THE REFINED STRUCTURES OF GOOSE LYSOZYME AND ITS COMPLEX WITH A BOUND TRISACCHARIDE SHOW THAT THE "GOOSE-TYPE LYSOZYMES LACK A CATALYTIC ASPARTATE
Descriptor: GOOSE LYSOZYME
Authors:Weaver, L.H, Gruetter, M.G, Matthews, B.W.
Deposit date:1994-05-05
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The refined structures of goose lysozyme and its complex with a bound trisaccharide show that the "goose-type" lysozymes lack a catalytic aspartate residue.
J.Mol.Biol., 245, 1995
178L
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BU of 178l by Molmil
Protein flexibility and adaptability seen in 25 crystal forms of T4 LYSOZYME
Descriptor: CHLORIDE ION, T4 LYSOZYME
Authors:Matsumura, M, Weaver, L, Zhang, X.-J, Matthews, B.W.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
1OWZ
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BU of 1owz by Molmil
T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 4-FluoroPhenEthyl Alcohol
Descriptor: 4-FLUOROPHENETHYL ALCOHOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2003-03-31
Release date:2004-04-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Testing a Flexible-receptor Docking Algorithm in a Model Binding Site
J.Mol.Biol., 337, 2004
1OVK
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BU of 1ovk by Molmil
T4 Lysozyme Cavity Mutant L99A/M102Q Bound with N-Allyl-Aniline
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2003-03-26
Release date:2004-04-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Testing a Flexible-receptor Docking Algorithm in a Model Binding Site
J.Mol.Biol., 337, 2004
1OVH
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BU of 1ovh by Molmil
T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 2-Chloro-6-Methyl-Aniline
Descriptor: 2-CHLORO-6-METHYL-ANILINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2003-03-26
Release date:2004-04-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Testing a Flexible-receptor Docking Algorithm in a Model Binding Site
J.Mol.Biol., 337, 2004
1OYU
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BU of 1oyu by Molmil
Long-Distance conformational changes in a protein engineered by modulated sequence duplication
Descriptor: Lysozyme
Authors:Sagermann, M, Gay, L, Matthews, B.W.
Deposit date:2003-04-07
Release date:2003-07-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Long-distance conformational changes in a protein engineered by modulated sequence duplication
Proc.Natl.Acad.Sci.USA, 100, 2003
1OWY
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BU of 1owy by Molmil
T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 2-Propyl-Aniline
Descriptor: 2-PROPYL-ANILINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2003-03-31
Release date:2004-04-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Testing a Flexible-receptor Docking Algorithm in a Model Binding Site
J.Mol.Biol., 337, 2004
1OV5
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BU of 1ov5 by Molmil
T4 Lysozyme Cavity Mutant L99a/M102Q Bound With 2-Allylphenol
Descriptor: 2-ALLYLPHENOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2003-03-25
Release date:2004-04-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Testing a Flexible-receptor Docking Algorithm in a Model Binding Site
J.Mol.Biol., 337, 2004
1OVJ
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BU of 1ovj by Molmil
T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 3-Fluoro-2-Methyl_Aniline
Descriptor: 3-FLUORO-2-METHYL-ANILINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2003-03-26
Release date:2004-04-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Testing a Flexible-receptor Docking Algorithm in a Model Binding Site
J.Mol.Biol., 337, 2004
1OV7
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BU of 1ov7 by Molmil
T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 2-Allyl-6-Methyl-Phenol
Descriptor: 2-ALLYL-6-METHYL-PHENOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2003-03-25
Release date:2004-04-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Testing a Flexible-receptor Docking Algorithm in a Model Binding Site
J.Mol.Biol., 337, 2004
1PE5
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BU of 1pe5 by Molmil
Thermolysin with tricyclic inhibitor
Descriptor: (6-METHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL)METHYLPHOSPHINATE, 3-METHYLBUTAN-1-AMINE, CALCIUM ION, ...
Authors:Juers, D, Holland, D, Morgan, B.P, Bartlett, P.A, Matthews, B.W.
Deposit date:2003-05-21
Release date:2004-06-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformational Constraint and Structural Complementarity in Thermolysin Inhibitors: Structures of Enzyme Complexes and Conclusions
To be Published
1PE7
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BU of 1pe7 by Molmil
Thermolysin with bicyclic inhibitor
Descriptor: 2-(4-METHYLPHENOXY)ETHYLPHOSPHINATE, 3-METHYLBUTAN-1-AMINE, CALCIUM ION, ...
Authors:Juers, D, Yusuff, N, Bartlett, P.A, Matthews, B.W.
Deposit date:2003-05-21
Release date:2004-06-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Conformational Constraint and Structural Complementarity in Thermolysin Inhibitors: Structures of Enzyme Complexes and Conclusions
To be Published
1PE8
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BU of 1pe8 by Molmil
Thermolysin with monocyclic inhibitor
Descriptor: 2-ETHOXYETHYLPHOSPHINATE, 3-METHYLBUTAN-1-AMINE, CALCIUM ION, ...
Authors:Juers, D, Pyun, H.-J, Bartlett, P.A, Matthews, B.W.
Deposit date:2003-05-21
Release date:2004-06-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational Constraint and Structural Complementarity in Thermolysin Inhibitors: Structures of Enzyme Complexes and Conclusions
To be Published

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