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2YH1
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BU of 2yh1 by Molmil
Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding
分子名称: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', SPLICING FACTOR U2AF 65 KDA SUBUNIT
著者Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M.
登録日2011-04-26
公開日2011-07-20
最終更新日2019-09-25
実験手法SOLUTION NMR
主引用文献Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Nature, 475, 2011
2YH0
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BU of 2yh0 by Molmil
Solution structure of the closed conformation of human U2AF65 tandem RRM1 and RRM2 domains
分子名称: SPLICING FACTOR U2AF 65 KDA SUBUNIT
著者Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M.
登録日2011-04-26
公開日2011-07-20
最終更新日2019-09-25
実験手法SOLUTION NMR
主引用文献Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Nature, 475, 2011
1SXE
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BU of 1sxe by Molmil
The solution structure of the Pointed (PNT) domain from the transcrition factor Erg
分子名称: Transcriptional regulator ERG
著者Mackereth, C.D, Schaerpf, M, Gentile, L.N, MacIntosh, S.E, Slupsky, C.M, McIntosh, L.P.
登録日2004-03-30
公開日2004-09-21
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Diversity in Structure and Function of the Ets Family PNT Domains.
J.Mol.Biol., 342, 2004
1SXD
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BU of 1sxd by Molmil
Solution Structure of the Pointed (PNT) Domain from mGABPa
分子名称: GA repeat binding protein, alpha
著者Mackereth, C.D, Schaerpf, M, Gentile, L.N, MacIntosh, S.E, Slupsky, C.M, McIntosh, L.P.
登録日2004-03-30
公開日2004-09-21
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Diversity in Structure and Function of the Ets Family PNT Domains.
J.Mol.Biol., 342, 2004
1EF4
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BU of 1ef4 by Molmil
SOLUTION STRUCTURE OF THE ESSENTIAL RNA POLYMERASE SUBUNIT RPB10 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
分子名称: DNA-DIRECTED RNA POLYMERASE, ZINC ION
著者Mackereth, C.D, Arrowsmith, C.H, Edwards, A.M, Mcintosh, L.P, Northeast Structural Genomics Consortium (NESG)
登録日2000-02-07
公開日2000-06-14
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA, 97, 2000
6SO9
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BU of 6so9 by Molmil
Mouse RBM20 RRM domain in complex with AUCUUA RNA
分子名称: AUCUUA, RNA-binding protein 20
著者Mackereth, C.D, Upadhyay, S.K.
登録日2019-08-29
公開日2019-11-06
最終更新日2020-05-13
実験手法SOLUTION NMR
主引用文献Structural basis of UCUU RNA motif recognition by splicing factor RBM20.
Nucleic Acids Res., 48, 2020
6SOE
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BU of 6soe by Molmil
Mouse RBM20 RRM domain
分子名称: RNA-binding protein 20
著者Mackereth, C.D, Upadhyay, S.K.
登録日2019-08-29
公開日2019-11-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis of UCUU RNA motif recognition by splicing factor RBM20.
Nucleic Acids Res., 48, 2020
6DG0
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BU of 6dg0 by Molmil
MEC-8 C-terminal RRM domain bound to AGCACA
分子名称: DNA (5'-D(*AP*GP*CP*AP*CP*A)-3'), Mec-8 protein
著者Mackereth, C.D, Soufari, H.
登録日2018-05-16
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.457 Å)
主引用文献Structure of MEC-8 RRM2 in complex with AGCACA
To Be Published
7QUU
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BU of 7quu by Molmil
Red1-Iss10 complex
分子名称: NURS complex subunit red1, Uncharacterized protein C7D4.14c
著者Mackereth, C.D, Kadlec, J, Laroussi, H.
登録日2022-01-18
公開日2022-09-07
最終更新日2022-11-16
実験手法SOLUTION NMR
主引用文献Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex.
Nat Commun, 13, 2022
1ZZP
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BU of 1zzp by Molmil
Solution structure of the F-actin binding domain of Bcr-Abl/c-Abl
分子名称: Proto-oncogene tyrosine-protein kinase ABL1
著者Hantschel, O, Wiesner, S, Guttler, T, Mackereth, C.D, Rix, L.L.R, Mikes, Z, Dehne, J, Gorlich, D, Sattler, M, Superti-Furga, G.
登録日2005-06-14
公開日2005-08-30
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structural Basis for the Cytoskeletal Association of Bcr-Abl/c-Abl.
Mol.Cell, 19, 2005
5BJR
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BU of 5bjr by Molmil
Crystal structure of the N-terminal RRM domain from MEC-8
分子名称: AMMONIUM ION, Mec-8 protein
著者Soufari, H, Mackereth, C.D.
登録日2016-10-22
公開日2017-01-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family.
RNA, 23, 2017
5TKZ
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BU of 5tkz by Molmil
MEC-8 N-terminal RRM bound to tandem GCAC ligand
分子名称: DNA (5'-D(*AP*GP*CP*AP*CP*AP*TP*TP*TP*TP*TP*TP*TP*TP*AP*GP*CP*AP*CP*A)-3'), Mec-8 protein
著者Soufari, H, Mackereth, C.D.
登録日2016-10-10
公開日2017-01-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.529 Å)
主引用文献Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family.
RNA, 23, 2017
6RQS
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BU of 6rqs by Molmil
RW16 peptide
分子名称: ARG-ARG-TRP-ARG-ARG-TRP-TRP-ARG-ARG-TRP-TRP-ARG-ARG-TRP-ARG-ARG
著者Jobin, M.-L, Grelard, A, Alves, I, Mackereth, C.D.
登録日2019-05-16
公開日2019-10-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Biophysical Insight on the Membrane Insertion of an Arginine-Rich Cell-Penetrating Peptide.
Int J Mol Sci, 20, 2019
2XC7
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BU of 2xc7 by Molmil
Solution Structure of PHAX-RBD in complex with ssRNA
分子名称: 5'-(AP*UP*CP*GP)-3', PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN
著者Mourao, A, Mackereth, C.D, Varrot, A, Cusack, S, Sattler, M.
登録日2010-04-18
公開日2010-04-28
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax.
RNA, 16, 2010
4CIO
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BU of 4cio by Molmil
RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA
分子名称: 5'-R(*GP*GP*UP*GP*UP*GP*CP)-3', PROTEIN SUP-12, ISOFORM A
著者Amrane, S, Mackereth, C.D.
登録日2013-12-12
公開日2014-09-03
最終更新日2014-09-17
実験手法SOLUTION NMR
主引用文献Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition
Nat.Commun., 5, 2014
4CH1
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BU of 4ch1 by Molmil
RRM domain from C. elegans SUP-12 bound to GGTGTGC DNA
分子名称: GGTGTGC, PROTEIN SUP-12, ISOFORM B
著者Amrane, S, Mackereth, C.D.
登録日2013-11-28
公開日2014-09-03
最終更新日2018-01-24
実験手法SOLUTION NMR
主引用文献Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition
Nat.Commun., 5, 2014
4CH0
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BU of 4ch0 by Molmil
RRM domain from C. elegans SUP-12
分子名称: PROTEIN SUP-12, ISOFORM B
著者Amrane, S, Mackereth, C.D.
登録日2013-11-27
公開日2014-09-03
最終更新日2016-05-04
実験手法SOLUTION NMR
主引用文献Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition
Nat.Commun., 5, 2014
2JUO
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BU of 2juo by Molmil
GABPa OST domain
分子名称: GA-binding protein alpha chain
著者Kang, H, Nelson, M.L, Mackereth, C.D, Schaerpf, M, Graves, B.J, McIntosh, L.P.
登録日2007-08-31
公開日2008-04-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Identification and structural characterization of a CBP/p300-binding domain from the ETS family transcription factor GABP alpha
J.Mol.Biol., 377, 2008
2L9B
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BU of 2l9b by Molmil
Heterodimer between Rna14p monkeytail domain and Rna15p hinge domain of the yeast CF IA complex
分子名称: mRNA 3'-end-processing protein RNA14, mRNA 3'-end-processing protein RNA15
著者Moreno-Morcillo, M, Minvielle-Sebastia, L, Fribourg, S, Mackereth, C.D.
登録日2011-02-07
公開日2011-04-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Locked Tether Formation by Cooperative Folding of Rna14p Monkeytail and Rna15p Hinge Domains in the Yeast CF IA Complex.
Structure, 19, 2011
8B7T
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BU of 8b7t by Molmil
CPSF73 CTD3
分子名称: CPSF73
著者Thore, S, Mackereth, C.
登録日2022-10-03
公開日2023-05-03
最終更新日2023-12-06
実験手法SOLUTION NMR
主引用文献Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin.
Open Biology, 13, 2023
8BA1
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BU of 8ba1 by Molmil
CTD12-CTD12 heterodimer from CPSF73 and CPSF100
分子名称: Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 3
著者Thore, S, Mackereth, C.
登録日2022-10-10
公開日2023-05-03
最終更新日2023-12-06
実験手法SOLUTION NMR
主引用文献Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin.
Open Biology, 13, 2023
6Q9T
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BU of 6q9t by Molmil
Protein-aromatic foldamer complex crystal structure
分子名称: 2-(8-azanyl-2-methanoyl-quinolin-4-yl)ethanoic acid, 6-(aminomethyl)pyridine-2-carboxylic acid, 8-azanyl-4-(2-hydroxy-2-oxoethyloxy)quinoline-2-carboxylic acid, ...
著者Post, S, Langlois d'Estaintot, B, Fischer, L, Granier, T, Huc, I.
登録日2018-12-18
公開日2019-09-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structure Elucidation of Helical Aromatic Foldamer-Protein Complexes with Large Contact Surface Areas.
Chemistry, 25, 2019
6HZX
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BU of 6hzx by Molmil
Protein-aromatic foldamer complex crystal structure
分子名称: 2-(8-azanyl-2-methanoyl-quinolin-4-yl)ethanoic acid, 6-(aminomethyl)pyridine-2-carboxylic acid, 8-azanyl-4-(2-hydroxy-2-oxoethyloxy)quinoline-2-carboxylic acid, ...
著者Post, S, Langlois d'Estaintot, B, Fischer, L, Granier, T, Huc, I.
登録日2018-10-24
公開日2019-09-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Structure Elucidation of Helical Aromatic Foldamer-Protein Complexes with Large Contact Surface Areas.
Chemistry, 25, 2019
5M9Z
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BU of 5m9z by Molmil
Second zinc-binding domain from yeast Pcf11
分子名称: Protein PCF11, ZINC ION
著者Mackereth, C.
登録日2016-11-02
公開日2017-08-02
最終更新日2019-05-08
実験手法SOLUTION NMR
主引用文献Distinct roles of Pcf11 zinc-binding domains in pre-mRNA 3'-end processing.
Nucleic Acids Res., 45, 2017
4BF8
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Fpr4 PPI domain
分子名称: FPR4
著者Monneau, Y, Mackereth, C.
登録日2013-03-15
公開日2013-07-31
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure and Activity of the Peptidyl-Prolyl Isomerase Domain from the Histone Chaperone Fpr4 Towards Histone H3 Proline Isomerization
J.Biol.Chem., 288, 2013

 

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