7W1K
| Crystal structure of carboxylesterase from Thermobifida fusca | 分子名称: | Carboxylesterase | 著者 | Han, X, Gerlis, H, Li, Z, Gao, J, Wei, R, Liu, W. | 登録日 | 2021-11-19 | 公開日 | 2022-11-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization Acs Catalysis, 12, 2022
|
|
7W1L
| Crystal structure of carboxylesterase mutant from Thermobifida fusca with C8X | 分子名称: | Carboxylesterase, bis(2-hydroxyethyl) benzene-1,4-dicarboxylate | 著者 | Han, X, Gerlis, H, Li, Z, Gao, J, Wei, R, Liu, W. | 登録日 | 2021-11-19 | 公開日 | 2022-11-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization Acs Catalysis, 12, 2022
|
|
7W1J
| Crystal structure of carboxylesterase from Thermobifida fusca with J1K | 分子名称: | 4-(2-hydroxyethylcarbamoyl)benzoic acid, Carboxylesterase | 著者 | Han, X, Gerlis, H, Li, Z, Gao, J, Wei, R, Liu, W. | 登録日 | 2021-11-19 | 公開日 | 2022-11-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization Acs Catalysis, 12, 2022
|
|
7W1I
| Crystal structure of carboxylesterase mutant from Thermobifida fusca with C8X and C9C | 分子名称: | 4-(2-hydroxyethyloxycarbonyl)benzoic acid, Carboxylesterase, bis(2-hydroxyethyl) benzene-1,4-dicarboxylate | 著者 | Han, X, Gerlis, H, Li, Z, Gao, J, Wei, R, Liu, W. | 登録日 | 2021-11-19 | 公開日 | 2022-11-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization Acs Catalysis, 12, 2022
|
|
7XS2
| Monomer structure of HtrA from Helicobacter pylori | 分子名称: | Periplasmic serine endoprotease DegP-like | 著者 | Cui, L, Liu, W. | 登録日 | 2022-05-12 | 公開日 | 2023-05-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structures and solution conformations of HtrA from Helicobacter pylori reveal pH-dependent oligomeric conversion and conformational rearrangements. Int.J.Biol.Macromol., 243, 2023
|
|
7XS0
| |
7TLL
| Structure of SARS-CoV-2 Mpro Omicron P132H in complex with Nirmatrelvir (PF-07321332) | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | 著者 | Greasley, S.E, Ferre, R.A, Plotnikova, O, Liu, W, Stewart, A.E. | 登録日 | 2022-01-18 | 公開日 | 2022-01-26 | 最終更新日 | 2022-06-15 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Structural basis for the in vitro efficacy of nirmatrelvir against SARS-CoV-2 variants. J.Biol.Chem., 298, 2022
|
|
7CUN
| The structure of human Integrator-PP2A complex | 分子名称: | Integrator complex subunit 1, Integrator complex subunit 11, Integrator complex subunit 2, ... | 著者 | Zheng, H, Qi, Y, Liu, W, Li, J, Wang, J, Xu, Y. | 登録日 | 2020-08-23 | 公開日 | 2020-11-25 | 最終更新日 | 2020-12-09 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase. Science, 370, 2020
|
|
7CWY
| Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP | 分子名称: | Decarboxylase | 著者 | Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R. | 登録日 | 2020-09-01 | 公開日 | 2021-09-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP to be published
|
|
7CWZ
| Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis K392A mutant in complex with the cofactor PLP and L-dopa | 分子名称: | Decarboxylase, L-DOPAMINE, MAGNESIUM ION, ... | 著者 | Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R. | 登録日 | 2020-09-01 | 公開日 | 2021-09-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis K392A mutant in complex with the cofactor PLP and L-dopa to be published
|
|
7CX0
| Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor carbidopa | 分子名称: | CARBIDOPA, Decarboxylase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R. | 登録日 | 2020-09-01 | 公開日 | 2021-09-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor carbidopa to be published
|
|
7CX1
| Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor methyl-tyrosine | 分子名称: | 4-[(2R)-2-(methylamino)propyl]phenol, Decarboxylase | 著者 | Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R. | 登録日 | 2020-09-01 | 公開日 | 2021-09-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor methyl-tyrosine to be published
|
|
7CWX
| Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis | 分子名称: | DI(HYDROXYETHYL)ETHER, Decarboxylase, GLYCEROL | 著者 | Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R. | 登録日 | 2020-09-01 | 公開日 | 2021-09-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis to be published
|
|
7D1G
| Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase GAPDH from Clostridium beijerinckii | 分子名称: | BETA-MERCAPTOETHANOL, Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION | 著者 | Chen, Y, Lan, J, Liu, W, Wang, L, Xu, Y. | 登録日 | 2020-09-14 | 公開日 | 2021-03-17 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase GAPDH from Clostridium beijerinckii To Be Published
|
|
7DCT
| |
7DCJ
| |
7DCU
| |
7DCS
| |
7VBA
| Structure of the pre state human RNA Polymerase I Elongation Complex | 分子名称: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(P*A*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*GP*C)-3'), DNA (5'-D(P*GP*CP*CP*AP*GP*AP*GP*AP*CP*AP*GP*CP*GP*AP*GP*TP*CP*AP*GP*CP*AP*A)-3'), ... | 著者 | Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y. | 登録日 | 2021-08-31 | 公開日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Structure of the human RNA polymerase I elongation complex. Cell Discov, 7, 2021
|
|
7VBC
| Back track state of human RNA Polymerase I Elongation Complex | 分子名称: | DNA (5'-D(*GP*TP*AP*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*G)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*AP*GP*CP*GP*TP*GP*TP*CP*AP*GP*CP*AP*AP*TP*A)-3'), DNA-directed RNA polymerase I subunit RPA1, ... | 著者 | Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y. | 登録日 | 2021-08-31 | 公開日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structure of the human RNA polymerase I elongation complex. Cell Discov, 7, 2021
|
|
7VBB
| Structure of the post state human RNA Polymerase I Elongation Complex | 分子名称: | DNA (25-MER), DNA (5'-D(*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*GP*CP*GP*A)-3'), DNA-directed RNA polymerase I subunit RPA1, ... | 著者 | Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y. | 登録日 | 2021-08-31 | 公開日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Structure of the human RNA polymerase I elongation complex. Cell Discov, 7, 2021
|
|
7EMF
| Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation | 分子名称: | Isoform 2 of Mediator of RNA polymerase II transcription subunit 16, Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, ... | 著者 | Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. | 登録日 | 2021-04-13 | 公開日 | 2021-05-05 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
|
|
7ENJ
| Human Mediator (deletion of MED1-IDR) in a Tail-bent conformation (MED-B) | 分子名称: | Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ... | 著者 | Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. | 登録日 | 2021-04-17 | 公開日 | 2021-05-19 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
|
|
7ENA
| TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | 登録日 | 2021-04-16 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (4.07 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
|
|
7ENC
| TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | 登録日 | 2021-04-16 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
|
|