Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7EUZ
DownloadVisualize
BU of 7euz by Molmil
Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis.
分子名称: (2S,3R)-2-azanyl-3-(1H-indol-3-yl)butanoic acid, Cupin domain-containing protein, FE (III) ION, ...
著者Li, T.L, Li, Y.S, Chen, M.H.
登録日2021-05-19
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.91028166 Å)
主引用文献Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
7EUE
DownloadVisualize
BU of 7eue by Molmil
Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis.
分子名称: 3-(1H-INDOL-3-YL)-2-OXOPROPANOIC ACID, Cupin domain-containing protein, FE (III) ION
著者Li, T.L, Li, Y.S, Chen, M.H.
登録日2021-05-17
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.08757067 Å)
主引用文献Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
7EUP
DownloadVisualize
BU of 7eup by Molmil
Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis.
分子名称: (2S,3R)-2-azanyl-3-phenyl-butanoic acid, Cupin domain-containing protein, FE (III) ION
著者Li, T.L, Li, Y.S, Chen, M.H.
登録日2021-05-18
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.11043429 Å)
主引用文献Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
6IIY
DownloadVisualize
BU of 6iiy by Molmil
Crystal structure of deacetylase triple mutant (Orf2*T) that involving in teicoplanin biosynthetic pathway
分子名称: COBALT (II) ION, IMIDAZOLE, deacetylase
著者Li, T.L, Huang, C.M.
登録日2018-10-08
公開日2019-10-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Teicoplanin Reprogrammed with the N-Acyl-Glucosamine Pharmacophore at the Penultimate Residue of Aglycone Acquires Broad-Spectrum Antimicrobial Activities Effectively Killing Gram-Positive and -Negative Pathogens.
Acs Infect Dis., 5, 2019
6IIX
DownloadVisualize
BU of 6iix by Molmil
The crystal structure of acyltransferase mutant, orf11*-W163A, in complex with octanoyl-CoA
分子名称: OCTANOYL-COENZYME A, SULFATE ION, acyltransferase
著者Li, T.L, Huang, C.M.
登録日2018-10-08
公開日2019-10-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Teicoplanin Reprogrammed with the N-Acyl-Glucosamine Pharmacophore at the Penultimate Residue of Aglycone Acquires Broad-Spectrum Antimicrobial Activities Effectively Killing Gram-Positive and -Negative Pathogens.
Acs Infect Dis., 5, 2019
7VZ6
DownloadVisualize
BU of 7vz6 by Molmil
The crystal structure of Non-hydrolyzing UDPGlcNAc 2-epimerase in complex with UDP-glucose
分子名称: Putative UDP-N-acetylglucosamine 2-epimerase, SODIUM ION, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Li, T.L, Rattinam, R.
登録日2021-11-15
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.092 Å)
主引用文献KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity.
Biomedicines, 10, 2022
7VZA
DownloadVisualize
BU of 7vza by Molmil
The crystal structure of Non-hydrolyzing UDPGlcNAc 2-epimerase in complex with UDP
分子名称: Putative UDP-N-acetylglucosamine 2-epimerase, SODIUM ION, URIDINE-5'-DIPHOSPHATE
著者Li, T.L, Rattinam, R.
登録日2021-11-15
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity.
Biomedicines, 10, 2022
7VYY
DownloadVisualize
BU of 7vyy by Molmil
The crystal structure of Non-hydrolyzing UDPGlcNAc 2-epimerase
分子名称: Putative UDP-N-acetylglucosamine 2-epimerase, SODIUM ION
著者Li, T.L, Rattinam, R.
登録日2021-11-15
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.443 Å)
主引用文献KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity.
Biomedicines, 10, 2022
4NE0
DownloadVisualize
BU of 4ne0 by Molmil
Crystal structure of non-heme iron oxygenase OrfP D157A mutant in complex with (3S)-hydroxy-L-Arg
分子名称: (2S,3S)-3-HYDROXYARGININE, FE (III) ION, L-arginine beta-hydroxylase, ...
著者Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L.
登録日2013-10-28
公開日2014-06-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms
Angew.Chem.Int.Ed.Engl., 53, 2014
4Q38
DownloadVisualize
BU of 4q38 by Molmil
The crystal structure of acyltransferase in complex with decanoyl-CoA and teicoplanin
分子名称: 2-amino-6-O-decanoyl-2-deoxy-beta-D-glucopyranose, COENZYME A, Putative uncharacterized protein tcp24, ...
著者Li, T.-L, Lyu, S.-Y, Liu, Y.-C, Chang, C.-Y, Huang, C.-J.
登録日2014-04-11
公開日2014-09-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus
J.Am.Chem.Soc., 136, 2014
4Q36
DownloadVisualize
BU of 4q36 by Molmil
The crystal structure of acyltransferase in complex with octanoyl-CoA and teicoplanin
分子名称: 2-amino-2-deoxy-beta-D-glucopyranose, OCTANOYL-COENZYME A, Putative uncharacterized protein tcp24, ...
著者Li, T.-L, Lyu, S.-Y, Liu, Y.-C, Chang, C.-Y, Huang, C.-J.
登録日2014-04-11
公開日2014-09-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus
J.Am.Chem.Soc., 136, 2014
7F0C
DownloadVisualize
BU of 7f0c by Molmil
Crystal structure of capreomycin phosphotransferase in complex with CMN IIA
分子名称: Capreomycin phosphotransferase, DPP-SER-DPP-UAL-MYN-KBE
著者Chang, C.Y, Pan, Y.C, Wang, Y.L, Toh, S.I.
登録日2021-06-03
公開日2022-05-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin.
Acs Chem.Biol., 17, 2022
7F0B
DownloadVisualize
BU of 7f0b by Molmil
Crystal structure of capreomycin phosphotransferase in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Capreomycin phosphotransferase
著者Chang, C.Y, Pan, Y.C, Wang, Y.L, Toh, S.I.
登録日2021-06-03
公開日2022-05-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin.
Acs Chem.Biol., 17, 2022
7F0A
DownloadVisualize
BU of 7f0a by Molmil
Crystal structure of capreomycin phosphotransferase
分子名称: Capreomycin phosphotransferase
著者Chang, C.Y, Pan, Y.C, Wang, Y.L, Toh, S.I.
登録日2021-06-03
公開日2022-05-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin.
Acs Chem.Biol., 17, 2022
7F0F
DownloadVisualize
BU of 7f0f by Molmil
Crystal structure of capreomycin phosphotransferase in complex with CMN IIB
分子名称: Capreomycin phosphotransferase, DPP-ALA-DPP-UAL-MYN-KBE
著者Chang, C.Y, Pan, Y.C, Wang, Y.L, Toh, S.I.
登録日2021-06-03
公開日2022-05-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin.
Acs Chem.Biol., 17, 2022
8GRI
DownloadVisualize
BU of 8gri by Molmil
Orf1-E312A-glycine-glycylthricin
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCINE, N-formimidoyl fortimicin A synthase, ...
著者Wang, Y.L, Li, T.L.
登録日2022-09-01
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.365 Å)
主引用文献N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.
Nat Commun, 14, 2023
7V4O
DownloadVisualize
BU of 7v4o by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
分子名称: 3,6,9,12,15-PENTAOXAHEPTADECANE, Beta-hydroxylase
著者Li, T.L, Saeid, M.Z.
登録日2021-08-13
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4N
DownloadVisualize
BU of 7v4n by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
分子名称: Beta-hydroxylase, FE (III) ION
著者Li, T.L, Saeid, M.Z.
登録日2021-08-13
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4M
DownloadVisualize
BU of 7v4m by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
分子名称: 2-OXOGLUTARIC ACID, Beta-hydroxylase, FE (III) ION, ...
著者Li, T.L, Saeid, M.Z.
登録日2021-08-13
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4P
DownloadVisualize
BU of 7v4p by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
分子名称: Beta-hydroxylase, FE (III) ION
著者Li, T.L, Saeid, M.Z.
登録日2021-08-13
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7XQA
DownloadVisualize
BU of 7xqa by Molmil
Orf1-glycine complex
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCINE, N-formimidoyl fortimicin A synthase
著者Wang, Y.L, Li, T.L.
登録日2022-05-07
公開日2023-05-31
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.
Nat Commun, 14, 2023
7XXD
DownloadVisualize
BU of 7xxd by Molmil
Orf1-sarcosine complex
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, N-formimidoyl fortimicin A synthase, SARCOSINE
著者Wang, Y.L, Li, T.L.
登録日2022-05-29
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.982 Å)
主引用文献N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.
Nat Commun, 14, 2023
7XX0
DownloadVisualize
BU of 7xx0 by Molmil
C281S glycylthricin complex
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCINE, N-formimidoyl fortimicin A synthase, ...
著者Wang, Y.L, Li, T.L.
登録日2022-05-27
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.
Nat Commun, 14, 2023
7XYE
DownloadVisualize
BU of 7xye by Molmil
The apo structure of Orf1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, N-formimidoyl fortimicin A synthase
著者Wang, Y.L, Li, T.L.
登録日2022-06-01
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.482 Å)
主引用文献N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.
Nat Commun, 14, 2023
7XXM
DownloadVisualize
BU of 7xxm by Molmil
Orf1-glycine-4-aminobutylthricin complex
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCINE, N-formimidoyl fortimicin A synthase, ...
著者Wang, Y.L, Li, T.L.
登録日2022-05-30
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.119 Å)
主引用文献N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.
Nat Commun, 14, 2023

219869

件を2024-05-15に公開中

PDB statisticsPDBj update infoContact PDBjnumon