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3U2P
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BU of 3u2p by Molmil
Crystal structure of N-terminal three extracellular domains of ErbB4/Her4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-4
著者Liu, P, Bouyain, S, Elgenbrot, C, Leahy, D.J.
登録日2011-10-04
公開日2011-11-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献The ErbB4 extracellular region retains a tethered-like conformation in the absence of the tether.
Protein Sci., 21, 2012
3TNU
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BU of 3tnu by Molmil
Heterocomplex of coil 2B domains of human intermediate filament proteins, keratin 5 (KRT5) and keratin 14 (KRT14)
分子名称: Keratin, type I cytoskeletal 14, type II cytoskeletal 5
著者Lee, C.H, Kim, M.S, Leahy, D.J, Coulombe, P.A.
登録日2011-09-02
公開日2012-06-20
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Structural basis for heteromeric assembly and perinuclear organization of keratin filaments.
Nat.Struct.Mol.Biol., 19, 2012
3U9U
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Crystal Structure of Extracellular Domain of Human ErbB4/Her4 in complex with the Fab fragment of mAb1479
分子名称: Fab Heavy Chain, Fab Light Chain, Receptor tyrosine-protein kinase erbB-4
著者Hollmen, M, Liu, P, Wildiers, H, Reinvall, I, Vandorpe, T, Smeets, A, Deraedt, K, Vahlberg, T, Joensuu, H, Leahy, D.J, Schoffski, P, Elenius, K.
登録日2011-10-19
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Proteolytic processing of ErbB4 in breast cancer.
Plos One, 7, 2012
2IBG
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BU of 2ibg by Molmil
Crystal Structure of Hedgehog Bound to the FNIII Domains of Ihog
分子名称: CG9211-PA, PHOSPHATE ION, Protein hedgehog
著者McLellan, J.S, Leahy, D.J.
登録日2006-09-11
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2IBB
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Crystal Structure of the First and Second FNIII Domains of Ihog
分子名称: CG9211-PA, SULFATE ION
著者McLellan, J.S, Leahy, D.J.
登録日2006-09-11
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2IC2
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Crystal Structure of the First FNIII Domain of Ihog
分子名称: CG9211-PA, SULFATE ION
著者McLellan, J.S, Leahy, D.J.
登録日2006-09-12
公開日2006-10-24
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2OGB
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BU of 2ogb by Molmil
Crystal structure of the C-terminal domain of mouse Nrdp1
分子名称: GLYCEROL, RING finger protein 41, THIOCYANATE ION
著者Bouyain, S, Leahy, D.J.
登録日2007-01-05
公開日2007-01-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-based mutagenesis of the substrate-recognition domain of Nrdp1/FLRF identifies the binding site for the receptor tyrosine kinase ErbB3.
Protein Sci., 16, 2007
1SZH
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BU of 1szh by Molmil
Crystal Structure of C. elegans HER-1
分子名称: ACETATE ION, Her-1 protein
著者Hamaoka, B.Y, Dann III, C.E, Geisbrecht, B.V, Leahy, D.J.
登録日2004-04-05
公開日2004-08-10
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A.
Proc.Natl.Acad.Sci.USA, 101, 2004
3N1Q
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Crystal Structure of DhhN bound to CDOFn3
分子名称: CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Desert hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1F
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Crystal Structure of IhhN bound to CDOFn3
分子名称: CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1M
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Crystal Structure of IhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1O
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BU of 3n1o by Molmil
Crystal structure of IhhN
分子名称: CALCIUM ION, Indian hedgehog protein, ZINC ION
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1G
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BU of 3n1g by Molmil
Crystal structure of DhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Desert hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1R
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BU of 3n1r by Molmil
Crystal Structure of ShhN
分子名称: CALCIUM ION, Sonic hedgehog protein, ZINC ION
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal Structure of ShhN
TO BE PUBLISHED
3N1P
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Crystal Structure of IhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
1N8Z
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Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Herceptin Fab (antibody) - heavy chain, Herceptin Fab (antibody) - light chain, ...
著者Cho, H.-S, Mason, K, Ramyar, K.X, Stanley, A.M, Gabelli, S.B, Denney Jr, D.W, Leahy, D.J.
登録日2002-11-21
公開日2003-02-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structure of the Extracellular Region of HER2 Alone and in Complex with the Herceptin Fab
Nature, 421, 2003
1N8Y
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Crystal structure of the extracellular region of rat HER2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, protooncoprotein
著者Cho, H.-S, Mason, K, Ramyar, K.X, Stanley, A.M, Gabelli, S.B, Denney Jr, D.W, Leahy, D.J.
登録日2002-11-21
公開日2003-02-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the Extracellular Region of HER2 Alone and in complex with the Herceptin Fab
Nature, 421, 2003
1OT8
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Structure of the Ankyrin Domain of the Drosophila Notch Receptor
分子名称: MAGNESIUM ION, Neurogenic locus Notch protein
著者Zweifel, M.E, Leahy, D.J, Hughson, F.M, Barrick, D.
登録日2003-03-21
公開日2003-10-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and stability of the ankyrin domain of the Drosophila Notch receptor
Protein Sci., 12, 2003
1VHH
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A POTENTIAL CATALYTIC SITE WITHIN THE AMINO-TERMINAL SIGNALLING DOMAIN OF SONIC HEDGEHOG
分子名称: SONIC HEDGEHOG, SULFATE ION, ZINC ION
著者Hall, T.M.T, Porter, J.A, Beachy, P.A, Leahy, D.J.
登録日1995-10-03
公開日1996-01-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog.
Nature, 378, 1995
1YN3
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BU of 1yn3 by Molmil
Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens
分子名称: truncated cell surface protein map-w
著者Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J.
登録日2005-01-23
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
1YN4
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Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens
分子名称: EapH1, ZINC ION
著者Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J.
登録日2005-01-23
公開日2005-03-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
1YN5
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Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens
分子名称: EapH2
著者Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J.
登録日2005-01-23
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
2A90
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Crystal Structure of the tandem WWE domain of Drosophila Deltex
分子名称: Deltex protein
著者Zweifel, M.E, Leahy, D.J, Barrick, D.
登録日2005-07-10
公開日2005-11-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure and Notch Receptor Binding of the Tandem WWE Domain of Deltex.
Structure, 13, 2005
2AHX
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Crystal structure of ErbB4/HER4 extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-4, SULFATE ION, ...
著者Bouyain, S, Longo, P.A, Li, S, Ferguson, K.M, Leahy, D.J.
登録日2005-07-28
公開日2005-09-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.396 Å)
主引用文献The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand
Proc.Natl.Acad.Sci.USA, 102, 2005
4X3X
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The crystal structure of Arc C-lobe
分子名称: Activity-regulated cytoskeleton-associated protein
著者Zhang, W, Ward, M, Leahy, D, Worley, P.
登録日2014-12-01
公開日2015-06-03
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of arc binding to synaptic proteins: implications for cognitive disease.
Neuron, 86, 2015

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