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7SAT
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BU of 7sat by Molmil
Structure of PorLM, the proton-powered motor that drives Type IX protein secretion
Descriptor: Por secretion system protein porL/gldL, Por secretion system protein porM/gldM
Authors:Hennell James, R, Deme, J.C, Lea, S.M.
Deposit date:2021-09-23
Release date:2022-03-23
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes.
Mbio, 13, 2022
7SAZ
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BU of 7saz by Molmil
Structure of GldLM, the proton-powered motor that drives Type IX protein secretion and gliding motility in Capnocytophaga canimorsus
Descriptor: GldL, GldM
Authors:Hennell James, R, Deme, J.C, Lea, S.M.
Deposit date:2021-09-23
Release date:2022-03-23
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes.
Mbio, 13, 2022
1RXL
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BU of 1rxl by Molmil
Solution structure of the engineered protein Afae-dsc
Descriptor: Afimbrial adhesin AFA-III
Authors:Anderson, K.L, Billington, J, Pettigrew, D, Cota, E, Roversi, P, Simpson, P, Chen, H.A, Urvil, P, du Merle, L, Barlow, P.N, Medof, M.E, Smith, R.A, Nowicki, B, Le Bouguenec, C, Lea, S.M, Matthews, S.
Deposit date:2003-12-18
Release date:2005-01-11
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:An atomic resolution model for assembly, architecture, and function of the Dr adhesins.
Mol.Cell, 15, 2004
1ZBA
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BU of 1zba by Molmil
Foot-and-Mouth Disease virus serotype A1061 complexed with oligosaccharide receptor.
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Coat protein VP1, Coat protein VP2, ...
Authors:Fry, E.E, Newman, J.W, Curry, S, Najjam, S, Jackson, T, Blakemore, W, Lea, S.M, Miller, L, Burman, A, King, A.M, Stuart, D.I.
Deposit date:2005-04-08
Release date:2005-06-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Foot-and-mouth disease virus serotype A1061 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation.
J.Gen.Virol., 86, 2005
1ZBE
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BU of 1zbe by Molmil
Foot-and Mouth Disease Virus Serotype A1061
Descriptor: Coat protein VP1, Coat protein VP2, Coat protein VP3, ...
Authors:Fry, E.E, Newman, J.W, Curry, S, Najjam, S, Jackson, T, Blakemore, W, Lea, S.M, Miller, L, Burman, A, King, A.M, Stuart, D.I.
Deposit date:2005-04-08
Release date:2005-06-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Foot-and-mouth disease virus serotype A1061 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation.
J.Gen.Virol., 86, 2005
6F2D
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BU of 6f2d by Molmil
A FliPQR complex forms the core of the Salmonella type III secretion system export apparatus.
Descriptor: Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR
Authors:Johnson, S, Kuhlen, L, Abrusci, P, Lea, S.M.
Deposit date:2017-11-24
Release date:2018-07-04
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the core of the type III secretion system export apparatus.
Nat. Struct. Mol. Biol., 25, 2018
2CM4
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BU of 2cm4 by Molmil
The complement inhibitor OmCI in complex with ricinoleic acid
Descriptor: ACETATE ION, COMPLEMENT INHIBITOR, RICINOLEIC ACID
Authors:Roversi, P, Johnson, S, Lissina, O, Paesen, G.C, Boland, W, Nunn, M.A, Lea, S.M.
Deposit date:2006-05-04
Release date:2007-05-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Structure of Omci, a Novel Lipocalin Inhibitor of the Complement System.
J.Mol.Biol., 369, 2007
2CM9
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BU of 2cm9 by Molmil
The complement inhibitor OmCI in complex with ricinoleic acid
Descriptor: ACETATE ION, COMPLEMENT INHIBITOR, RICINOLEIC ACID
Authors:Roversi, P, Johnson, S, Lissina, O, Paesen, G.C, Boland, W, Nunn, M.A, Lea, S.M.
Deposit date:2006-05-04
Release date:2007-05-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structure of Omci, a Novel Lipocalin Inhibitor of the Complement System.
J.Mol.Biol., 369, 2007
6H3J
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BU of 6h3j by Molmil
Structural snapshots of the Type 9 protein translocon Plug-complex
Descriptor: Peptidyl-prolyl cis-trans isomerase, Plug, Protein involved in gliding motility SprA
Authors:Deme, J.C, Lea, S.M.
Deposit date:2018-07-18
Release date:2018-11-07
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Type 9 secretion system structures reveal a new protein transport mechanism.
Nature, 564, 2018
6H3I
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BU of 6h3i by Molmil
Structural snapshots of the Type 9 protein translocon
Descriptor: Peptidyl-prolyl cis-trans isomerase, PorV, Protein involved in gliding motility SprA
Authors:Deme, J.C, Lea, S.M.
Deposit date:2018-07-18
Release date:2018-11-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Type 9 secretion system structures reveal a new protein transport mechanism.
Nature, 564, 2018
4V2K
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BU of 4v2k by Molmil
Crystal structure of the thiosulfate dehydrogenase TsdA in complex with thiosulfate
Descriptor: HEME C, THIOSULFATE, THIOSULFATE DEHYDROGENASE
Authors:Grabarczyk, D.B, Chappell, P.E, Eisel, B, Johnson, S, Lea, S.M, Berks, B.C.
Deposit date:2014-10-10
Release date:2015-02-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Mechanism of Thiosulfate Oxidation in the Soxa Family of Cysteine-Ligated Cytochromes
J.Biol.Chem., 290, 2015
4V1J
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BU of 4v1j by Molmil
Structure of Neisseria meningitidis Major Pillin
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, FIMBRIAL PROTEIN
Authors:Harding, R.J, Exley, R, Tang, C.M, Caesar, J.J.E, Lea, S.M.
Deposit date:2014-09-29
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Tstructure of Neisseria Meningitidis Major Pillin
To be Published
4UWQ
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BU of 4uwq by Molmil
Crystal structure of the disulfide-linked complex of the thiosulfodyrolase SoxB with the carrier-protein SoxYZ from Thermus thermophilus
Descriptor: MANGANESE (II) ION, SOXY PROTEIN, SOXZ, ...
Authors:Grabarczyk, D.B, Chappell, P.E, Johnson, S, Stelzl, L.S, Lea, S.M, Berks, B.C.
Deposit date:2014-08-14
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Structural Basis for Specificity and Promiscuity in a Carrier Protein/Enzyme System from the Sulfur Cycle
Proc.Natl.Acad.Sci.USA, 112, 2015
4TT9
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BU of 4tt9 by Molmil
Structure of the C-terminal SpoA domain of Shigella flexneri Spa33
Descriptor: 1,2-ETHANEDIOL, Surface presentation of antigens protein SpaO
Authors:McDowell, M.A, Johnson, S, Lea, S.M.
Deposit date:2014-06-20
Release date:2015-06-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Characterisation of Shigella Spa33 and Thermotoga FliM/N reveals a new model for C-ring assembly in T3SS.
Mol.Microbiol., 99, 2016
8GLJ
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BU of 8glj by Molmil
The Type 9 Secretion System in vitro assembled, FspA-CTD substrate bound complex
Descriptor: Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, Por secretion system C-terminal sorting domain-containing protein, ...
Authors:Deme, J.C, Lea, S.M.
Deposit date:2023-03-22
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The Type 9 Secretion System caught in the act of transport
Nat Microbiol, 2024
8GLK
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BU of 8glk by Molmil
The Type 9 Secretion System dGldL peak II, NucA substrate bound complex
Descriptor: Endonuclease I, Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, ...
Authors:Deme, J.C, Lea, S.M.
Deposit date:2023-03-22
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The Type 9 Secretion System caught in the act of transport
Nat Microbiol, 2024
8GLM
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BU of 8glm by Molmil
The Type 9 Secretion System in vivo assembled, RemZ substrate bound complex - conformation 1
Descriptor: Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, Protein involved in gliding motility SprA, ...
Authors:Deme, J.C, Lea, S.M.
Deposit date:2023-03-22
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:The Type 9 Secretion System caught in the act of transport
Nat Microbiol, 2024
8GLN
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BU of 8gln by Molmil
The Type 9 Secretion System in vivo assembled, RemZ substrate bound complex - conformation 2
Descriptor: Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, Protein involved in gliding motility SprA, ...
Authors:Deme, J.C, Lea, S.M.
Deposit date:2023-03-22
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:The Type 9 Secretion System caught in the act of transport
Nat Microbiol, 2024
8GL6
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BU of 8gl6 by Molmil
The Type 9 Secretion System in vitro assembled, RemA-CTD substrate bound complex
Descriptor: Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, Protein involved in gliding motility SprA, ...
Authors:Deme, J.C, Lea, S.M.
Deposit date:2023-03-21
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The Type 9 Secretion System caught in the act of transport
Nat Microbiol, 2024
8GL8
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BU of 8gl8 by Molmil
The Type 9 Secretion System Extended Translocon - SprA-PorV-PPI-RemZ-SkpA-SprE complex
Descriptor: Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, Periplasmic chaperone for outer membrane proteins Skp, ...
Authors:Deme, J.C, Lea, S.M.
Deposit date:2023-03-21
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:The Type 9 Secretion System caught in the act of transport
Nat Microbiol, 2024
2V6L
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BU of 2v6l by Molmil
Molecular Model of a Type III Secretion System Needle
Descriptor: MXIH
Authors:Deane, J.E, Roversi, P, Cordes, F.S, Johnson, S, Kenjale, R, Daniell, S, Booy, F, Picking, W.L, Picking, W.D, Blocker, A.J, Lea, S.M.
Deposit date:2007-07-19
Release date:2007-07-31
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Molecular model of a type III secretion system needle: Implications for host-cell sensing.
Proc. Natl. Acad. Sci. U.S.A., 103, 2006
7AKV
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BU of 7akv by Molmil
The cryo-EM structure of the Vag8-C1 inhibitor complex
Descriptor: Plasma protease C1 inhibitor, Vag8
Authors:Johnson, S, Lea, S.M, Deme, J.C, Furlong, E, Dhillon, A.
Deposit date:2020-10-02
Release date:2021-06-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex.
Mbio, 12, 2021
7ALJ
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BU of 7alj by Molmil
Structure of Drosophila Notch EGF domains 11-13
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus Notch protein, ...
Authors:Suckling, R, Johnson, S, Lea, S.M.
Deposit date:2020-10-06
Release date:2021-08-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.
Embo Rep., 22, 2021
7ALK
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BU of 7alk by Molmil
Structure of Drosophila C2-DSL-EGF1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neurogenic locus protein delta, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Suckling, R, Johnson, S, Lea, S.M.
Deposit date:2020-10-06
Release date:2021-08-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.
Embo Rep., 22, 2021
7ALT
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BU of 7alt by Molmil
Structure of Drosophila Serrate C2-DSL-EGF1-EGF2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Suckling, R, Johnson, S, Lea, S.M.
Deposit date:2020-10-07
Release date:2021-08-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.
Embo Rep., 22, 2021

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