5BT3
| Crystal structure of EP300 bromodomain in complex with SGC-CBP30 chemical probe | Descriptor: | 2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-benzimidazole, Histone acetyltransferase p300, ISOPROPYL ALCOHOL | Authors: | Tallant, C, Hay, D, Krojer, T, Nunez-Alonso, G, Picaud, S, Newman, J.A, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brennan, P.E, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2015-06-02 | Release date: | 2015-07-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Crystal structure of EP300 bromodomain in complex with a 3,5-dimethylisoxazol ligand To Be Published
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4GPJ
| Crystal Structure of the first bromodomain of human BRD4 in complex with a isoxazolylbenzimidazole ligand | Descriptor: | (1R)-6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-phenyl-2,3-dihydro-1H-inden-1-ol, 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ... | Authors: | Filippakopoulos, P, Picaud, S, Qi, J, Felletar, I, Heightman, T.D, Brennan, P, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2012-08-21 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains. Medchemcomm, 4, 2013
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5HOC
| p73 homo-tetramerization domain mutant II | Descriptor: | Tumor protein p73 | Authors: | Coutandin, D, Krojer, T, Salah, E, Mathea, S, Sumyk, M, Knapp, S, Dotsch, V. | Deposit date: | 2016-01-19 | Release date: | 2016-10-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.36007786 Å) | Cite: | Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization. Cell Death Differ., 23, 2016
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4FR4
| Crystal structure of human serine/threonine-protein kinase 32A (YANK1) | Descriptor: | 1,2-ETHANEDIOL, STAUROSPORINE, Serine/threonine-protein kinase 32A | Authors: | Chaikuad, A, Elkins, J.M, Krojer, T, Mahajan, P, Goubin, S, Szklarz, M, Tumber, A, Wang, J, Savitsky, P, Shrestha, B, Daga, N, Picaud, S, Fedorov, O, Allerston, C.K, Latwiel, S.V.A, Vollmar, M, Canning, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2012-06-26 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Crystal structure of human serine/threonine-protein kinase 32A (YANK1) To be Published
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7GAL
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z291279160 | Descriptor: | 1,2-ETHANEDIOL, 1-[2-(trifluoromethyloxy)phenyl]thiourea, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAN
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z56767614 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAB
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1255402624 | Descriptor: | 1,2-ETHANEDIOL, 2-tert-butylbenzene-1,4-diol, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAM
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z373768900 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAQ
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z755044716 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GA8
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198158918 | Descriptor: | 1,2-ETHANEDIOL, 1H-indazole-3-carbonitrile, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAE
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1688504114 | Descriptor: | 1,2-ETHANEDIOL, 2-cyano-~{N}-(1,3,5-trimethylpyrazol-4-yl)ethanamide, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAG
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z198195770 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAO
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z57450788 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAU
| PanDDA analysis group deposition of ground-state model of MAP1LC3B | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-11 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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7GAH
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z2033637875 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAP
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z728939702 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GA9
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198177230 | Descriptor: | (2M)-2-(2-methoxyphenyl)-1,3,4-oxadiazole, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAR
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z820676436 | Descriptor: | 1,2-ETHANEDIOL, 2-(4-bromanylpyrazol-1-yl)-~{N}-cyclopropyl-~{N}-methyl-ethanamide, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAD
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1667545918 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAS
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z952016136 | Descriptor: | 1,2-ETHANEDIOL, 4-chloro-1H-benzimidazole, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAA
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198233191 | Descriptor: | (4S)-imidazo[1,2-a]pyrimidine-5,7-diol, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAF
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z183352334 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAC
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1456069604 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAI
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z212122838 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAJ
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z285233820 | Descriptor: | (5M)-5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-amine, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | PanDDA analysis group deposition To Be Published
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