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1PQV
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BU of 1pqv by Molmil
RNA polymerase II-TFIIS complex
分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ...
著者Kettenberger, H, Armache, K.-J, Cramer, P.
登録日2003-06-19
公開日2003-08-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Architecture of the RNA Polymerase II-TFIIS Complex and Implications for mRNA Cleavage
Cell(Cambridge,Mass.), 114, 2003
2B63
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BU of 2b63 by Molmil
Complete RNA Polymerase II-RNA inhibitor complex
分子名称: 31-MER, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ...
著者Kettenberger, H, Eisenfuehr, A, Brueckner, F, Theis, M, Famulok, M, Cramer, P.
登録日2005-09-30
公開日2005-12-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs
Nat.Struct.Mol.Biol., 13, 2006
1Y77
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BU of 1y77 by Molmil
Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP
分子名称: 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*T*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*G)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ...
著者Kettenberger, H, Armache, K.-J, Cramer, P.
登録日2004-12-08
公開日2005-01-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
Mol.Cell, 16, 2004
1Y1V
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BU of 1y1v by Molmil
Refined RNA Polymerase II-TFIIS complex
分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ...
著者Kettenberger, H, Armache, K.-J, Cramer, P.
登録日2004-11-19
公開日2004-12-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.
Mol.Cell, 16, 2004
1Y1Y
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BU of 1y1y by Molmil
RNA Polymerase II-TFIIS-DNA/RNA complex
分子名称: 5'-D(P*TP*AP*CP*GP*CP*CP*T)-3', 5'-R(P*AP*GP*GP*C)-3', DNA-directed RNA polymerase II 13.6 kDa polypeptide, ...
著者Cramer, P, Kettenberger, H, Armache, K.-J.
登録日2004-11-19
公開日2004-12-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.
Mol.Cell, 16, 2004
1Y1W
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BU of 1y1w by Molmil
Complete RNA Polymerase II elongation complex
分子名称: 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*AP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ...
著者Cramer, P, Kettenberger, H, Armache, K.-J.
登録日2004-11-19
公開日2005-01-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
Mol.Cell, 16, 2004
4IMK
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BU of 4imk by Molmil
Uncrossed Fab binding to human Angiopoietin 2
分子名称: GLYCEROL, Heavy Chain, Light Chain, ...
著者Fenn, S, Schiller, C, Griese, J.J, Hopfner, K.-P, Kettenberger, H.
登録日2013-01-03
公開日2013-04-17
最終更新日2013-05-22
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
4IML
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BU of 4iml by Molmil
CrossFab binding to human Angiopoietin 2
分子名称: Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL
著者Fenn, S, Schiller, C, Griese, J, Hopfner, K.-P, Kettenberger, H.
登録日2013-01-03
公開日2013-04-17
最終更新日2013-05-22
実験手法X-RAY DIFFRACTION (2.931 Å)
主引用文献Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
6T9E
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BU of 6t9e by Molmil
Crystal structure of a bispecific DutaFab in complex with human PDGF
分子名称: DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B
著者Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H.
登録日2019-10-28
公開日2020-12-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.989 Å)
主引用文献DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.
Nat Commun, 12, 2021
6T9D
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BU of 6t9d by Molmil
Crystal structure of a bispecific DutaFab in complex with human VEGF121
分子名称: VP mat DutaFab VH chain, VP mat DutaFab VL chain, Vascular endothelial growth factor A
著者Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H.
登録日2019-10-28
公開日2020-12-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.905 Å)
主引用文献DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.
Nat Commun, 12, 2021
1NT9
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BU of 1nt9 by Molmil
Complete 12-subunit RNA polymerase II
分子名称: DNA-DIRECTED RNA POLYMERASE II 13.6 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT, ...
著者Armache, K.-J, Kettenberger, H, Cramer, P.
登録日2003-01-29
公開日2003-04-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Architecture of initiation-competent 12-subunit RNA polymerase II
Proc.Natl.Acad.Sci.USA, 100, 2003
6ELJ
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BU of 6elj by Molmil
FAB Fragment. AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
分子名称: fAB heavy chain, fAB light chain
著者Benz, J, Weigand, S, Dengl, S, Schlothauer, T, Auer, J, Ehler, A, Kettenberger, H, Lorenz, S, Hirschheydt, T, Georges, G.
登録日2017-09-29
公開日2017-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
To Be Published
6ELE
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BU of 6ele by Molmil
FAB Fragment. AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
分子名称: 1,2-ETHANEDIOL, SODIUM ION, fAB heavy chain, ...
著者Benz, J, Weigand, S, Dengl, S, Schlothauer, T, Auer, J, Ehler, A, Kettenberger, H, Lorenz, S, Hirschheydt, T, Georges, G.
登録日2017-09-28
公開日2017-11-08
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
To Be Published
6ELL
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BU of 6ell by Molmil
FAB Fragment. AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
分子名称: fAB heavy chain, fAB light chain
著者Benz, J, Weigand, S, Dengl, S, Schlothauer, T, Auer, J, Ehler, A, Kettenberger, H, Lorenz, S, Hirschheydt, T, Georges, G.
登録日2017-09-29
公開日2017-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
To Be Published
6EMJ
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BU of 6emj by Molmil
FAB Fragment. AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
分子名称: SODIUM ION, fAB heavy chain, fAb light chain
著者Benz, J, Weigand, S, Dengl, S, Schlothauer, T, Auer, J, Ehler, A, Kettenberger, H, Lorenz, S, Hirschheydt, T, Georges, G.
登録日2017-10-02
公開日2017-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
To Be Published

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件を2024-04-24に公開中

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