5PTP
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5C9C
| CRYSTAL STRUCTURE OF BRAF(V600E) IN COMPLEX WITH LY3009120 COMPND | 分子名称: | 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea, CHLORIDE ION, Serine/threonine-protein kinase B-raf | 著者 | Edwards, T, Abendroth, J, Chun, L. | 登録日 | 2015-06-26 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers. Cancer Cell, 28, 2015
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2MX4
| NMR structure of Phosphorylated 4E-BP2 | 分子名称: | Eukaryotic translation initiation factor 4E-binding protein 2 | 著者 | Bah, A, Forman-Kay, J, Vernon, R, Siddiqui, Z, Krzeminski, M, Muhandiram, R, Zhao, C, Sonenberg, N, Kay, L. | 登録日 | 2014-12-10 | 公開日 | 2015-01-07 | 最終更新日 | 2015-03-18 | 実験手法 | SOLUTION NMR | 主引用文献 | Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch. Nature, 519, 2015
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1NTP
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