2QN0
 
 | | Structure of Botulinum neurotoxin serotype C1 light chain protease | | 分子名称: | Neurotoxin, ZINC ION | | 著者 | Jin, R, Sikorra, S, Stegmann, C.M, Pich, A, Binz, T, Brunger, A.T. | | 登録日 | 2007-07-17 | | 公開日 | 2007-09-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural and biochemical studies of botulinum neurotoxin serotype C1 light chain protease: implications for dual substrate specificity.
Biochemistry, 46, 2007
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3H5W
 | | Crystal structure of the GluR2-ATD in space group P212121 without solvent | | 分子名称: | Glutamate receptor 2 | | 著者 | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | | 登録日 | 2009-04-22 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.686 Å) | | 主引用文献 | Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
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3H5V
 | | Crystal structure of the GluR2-ATD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 | | 著者 | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | | 登録日 | 2009-04-22 | | 公開日 | 2009-06-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
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2AL5
 | | Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with fluoro-willardiine and aniracetam | | 分子名称: | 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE, 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2 | | 著者 | Jin, R, Clark, S, Weeks, A.M, Dudman, J.T, Gouaux, E, Partin, K.M. | | 登録日 | 2005-08-04 | | 公開日 | 2005-10-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Mechanism of positive allosteric modulators acting on AMPA receptors.
J.Neurosci., 25, 2005
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2AL4
 | | CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH quisqualate and CX614. | | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE, Glutamate receptor 2, ... | | 著者 | Jin, R, Clark, S, Weeks, A.M, Dudman, J.T, Gouaux, E, Partin, K.M. | | 登録日 | 2005-08-04 | | 公開日 | 2005-10-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism of positive allosteric modulators acting on AMPA receptors.
J.Neurosci., 25, 2005
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1MY3
 | | crystal structure of glutamate receptor ligand-binding core in complex with bromo-willardiine in the Zn crystal form | | 分子名称: | 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION | | 著者 | Jin, R, Gouaux, E. | | 登録日 | 2002-10-03 | | 公開日 | 2003-06-10 | | 最終更新日 | 2017-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core:
Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
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1MY0
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1MXU
 | | CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) in complex with bromo-willardiine (Control for the crystal titration experiments) | | 分子名称: | 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION | | 著者 | Jin, R, Gouaux, E. | | 登録日 | 2002-10-03 | | 公開日 | 2003-06-10 | | 最終更新日 | 2017-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
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1MXV
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1MY2
 | | crystal titration experiment (AMPA complex control) | | 分子名称: | (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION | | 著者 | Jin, R, Gouaux, E. | | 登録日 | 2002-10-03 | | 公開日 | 2003-06-10 | | 最終更新日 | 2017-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
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1MXY
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1MXW
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1MY4
 | | crystal structure of glutamate receptor ligand-binding core in complex with iodo-willardiine in the Zn crystal form | | 分子名称: | 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION | | 著者 | Jin, R, Gouaux, E. | | 登録日 | 2002-10-03 | | 公開日 | 2003-06-10 | | 最終更新日 | 2017-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
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1MXX
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1MXZ
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1MY1
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1MM7
 | | Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Quisqualate in a Zinc Crystal Form at 1.65 Angstroms Resolution | | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION | | 著者 | Jin, R, Horning, M, Mayer, M.L, Gouaux, E. | | 登録日 | 2002-09-03 | | 公開日 | 2003-02-04 | | 最終更新日 | 2017-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Mechanism of Activation and Selectivity in a Ligand-Gated Ion Channel: Structural and Functional Studies of GluR2 and Quisqualate
Biochemistry, 41, 2003
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1MM6
 | | crystal structure of the GluR2 ligand binding core (S1S2J) in complex with quisqualate in a non zinc crystal form at 2.15 angstroms resolution | | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, GLYCEROL, ... | | 著者 | Jin, R, Horning, M, Mayer, M.L, Gouaux, E. | | 登録日 | 2002-09-03 | | 公開日 | 2003-02-04 | | 最終更新日 | 2017-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Mechanism of activation and selectivity in a ligand-gated ion channel: Structural and functional studies of GluR2 and quisqualate
Biochemistry, 41, 2002
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1MQG
 | | Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Iodo-Willardiine at 2.15 Angstroms Resolution | | 分子名称: | 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLYCEROL, SULFATE ION, ... | | 著者 | Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E. | | 登録日 | 2002-09-16 | | 公開日 | 2003-08-05 | | 最終更新日 | 2017-05-10 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
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1MQH
 | | Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Bromo-Willardiine at 1.8 Angstroms Resolution | | 分子名称: | 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, glutamate receptor 2 | | 著者 | Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E. | | 登録日 | 2002-09-16 | | 公開日 | 2003-08-05 | | 最終更新日 | 2017-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
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1MQI
 | | Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Fluoro-Willardiine at 1.35 Angstroms Resolution | | 分子名称: | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, glutamate receptor 2 | | 著者 | Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E. | | 登録日 | 2002-09-16 | | 公開日 | 2003-08-05 | | 最終更新日 | 2017-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
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1MQJ
 | | Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution | | 分子名称: | 2-AMINO-3-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ZINC ION, glutamate receptor 2 | | 著者 | Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E. | | 登録日 | 2002-09-16 | | 公開日 | 2003-08-05 | | 最終更新日 | 2017-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
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1ZC4
 | | Crystal structure of the Ral-binding domain of Exo84 in complex with the active RalA | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Ral-A, ... | | 著者 | Jin, R, Junutula, J.R, Matern, H.T, Ervin, K.E, Scheller, R.H, Brunger, A.T. | | 登録日 | 2005-04-10 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase.
Embo J., 24, 2005
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1ZC3
 | | Crystal structure of the Ral-binding domain of Exo84 in complex with the active RalA | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Ral-A, ... | | 著者 | Jin, R, Junutula, J.R, Matern, H.T, Ervin, K.E, Scheller, R.H, Brunger, A.T. | | 登録日 | 2005-04-10 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase.
Embo J., 24, 2005
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2NM1
 | | Structure of BoNT/B in complex with its protein receptor | | 分子名称: | Botulinum neurotoxin type B, Synaptotagmin-2 | | 著者 | Jin, R, Rummel, A, Binz, T, Brunger, A.T. | | 登録日 | 2006-10-20 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.
Nature, 444, 2006
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