4KQM
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3NB0
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3NAZ
| Basal state form of Yeast Glycogen Synthase | Descriptor: | Glycogen [starch] synthase isoform 2, PEPTIDE, SULFATE ION | Authors: | Baskaran, S, Hurley, T.D. | Deposit date: | 2010-06-02 | Release date: | 2010-10-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for glucose-6-phosphate activation of glycogen synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
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3NCH
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3O3C
| Glycogen synthase basal state UDP complex | Descriptor: | Glycogen [starch] synthase isoform 2, SULFATE ION, URIDINE-5'-DIPHOSPHATE | Authors: | Baskaran, S, Hurley, T.D. | Deposit date: | 2010-07-23 | Release date: | 2010-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.512 Å) | Cite: | Structural basis for glucose-6-phosphate activation of glycogen synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
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3RSZ
| Maltodextran bound basal state conformation of yeast glycogen synthase isoform 2 | Descriptor: | Glycogen [starch] synthase isoform 2, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Baskaran, S, Hurley, T.D. | Deposit date: | 2011-05-02 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.009 Å) | Cite: | Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen. J.Biol.Chem., 286, 2011
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1ZUM
| Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, Apo Form | Descriptor: | 1,2-ETHANEDIOL, Aldehyde dehydrogenase, GUANIDINE, ... | Authors: | Larson, H.N, Weiner, H, Hurley, T.D. | Deposit date: | 2005-05-31 | Release date: | 2005-06-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Disruption of the coenzyme binding site and dimer interface revealed in the crystal structure of mitochondrial aldehyde dehydrogenase "asian" variant J.Biol.Chem., 280, 2005
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1U3T
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1U3V
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1U3U
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1U3W
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2ONO
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2ONM
| Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with NAD+ | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aldehyde dehydrogenase, ... | Authors: | Larson, H.N, Hurley, T.D. | Deposit date: | 2007-01-24 | Release date: | 2007-03-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487. J.Biol.Chem., 282, 2007
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2ONN
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2ONP
| Arg475Gln Mutant of Human Mitochondrial Aldehyde Dehydrogenase, complexed with NAD+ | Descriptor: | 1,2-ETHANEDIOL, Aldehyde dehydrogenase, GUANIDINE, ... | Authors: | Larson, H.N, Hurley, T.D. | Deposit date: | 2007-01-24 | Release date: | 2007-03-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487. J.Biol.Chem., 282, 2007
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2PS1
| S. cerevisiae orotate phosphoribosyltransferase complexed with orotic acid and PRPP | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, OROTIC ACID, ... | Authors: | Gonzalez-Segura, L, Hurley, T.D, McClard, R.W. | Deposit date: | 2007-05-04 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Ternary complex formation and induced asymmetry in orotate phosphoribosyltransferase. Biochemistry, 46, 2007
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2PRZ
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2PRY
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1O02
| Human mitochondrial aldehyde dehydrogenase complexed with NADH in the presence of Mg2+ | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Aldehyde dehydrogenase, ... | Authors: | Perez-Miller, S.J, Hurley, T.D. | Deposit date: | 2003-02-20 | Release date: | 2003-06-24 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase Biochemistry, 42, 2003
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1O00
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1NZX
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1NZW
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1NZZ
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1O01
| Human mitochondrial aldehyde dehydrogenase complexed with crotonaldehyde, NAD(H) and Mg2+ | Descriptor: | (2E)-BUT-2-ENAL, 1,2-ETHANEDIOL, Aldehyde dehydrogenase, ... | Authors: | Perez-Miller, S.J, Hurley, T.D. | Deposit date: | 2003-02-20 | Release date: | 2003-06-24 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase Biochemistry, 42, 2003
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1O04
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