2P2C
 
 | | Inhibition of caspase-2 by a designed ankyrin repeat protein (DARPin) | | Descriptor: | Caspase-2 | | Authors: | Roschitzki Voser, H, Briand, C, Capitani, G, Gruetter, M.G. | | Deposit date: | 2007-03-07 | | Release date: | 2007-05-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.24 Å) | | Cite: | Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism.
Structure, 15, 2007
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154L
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153L
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4I2O
 | | The Structure of FixK2 from Bradyrhizobium japonicum | | Descriptor: | FixK2 protein, Promoter of fixK2 direct target, fixN, ... | | Authors: | Bonnet, M, Kurz, M, Mesa, S, Briand, C, Hennecke, H, Gruetter, M.G. | | Deposit date: | 2012-11-22 | | Release date: | 2013-04-10 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | The Structure of Bradyrhizobium japonicum Transcription Factor FixK2 Unveils Sites of DNA Binding and Oxidation.
J.Biol.Chem., 288, 2013
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4J8Y
 | | E3_5 DARPin D77S mutant | | Descriptor: | DARPin_E3_5_D77S | | Authors: | Seeger, M.A, Gruetter, M.G. | | Deposit date: | 2013-02-15 | | Release date: | 2013-08-14 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity.
Protein Sci., 22, 2013
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4Q4A
 | | Improved model of AMP-PNP bound TM287/288 | | Descriptor: | ABC transporter, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Hohl, M, Gruetter, M.G, Seeger, M.A. | | Deposit date: | 2014-04-14 | | Release date: | 2014-07-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4Q4J
 | | Structure of crosslinked TM287/288_S498C_S520C mutant | | Descriptor: | ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288 | | Authors: | Hohl, M, Schoeppe, J, Gruetter, M.G, Seeger, M.A. | | Deposit date: | 2014-04-14 | | Release date: | 2014-07-16 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4Q7K
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4Q7L
 | | Structure of NBD288 of TM287/288 | | Descriptor: | NICKEL (II) ION, Uncharacterized ABC transporter ATP-binding protein TM_0288 | | Authors: | Bukowska, M.A, Hohl, M, Gruetter, M.G, Seeger, M.A. | | Deposit date: | 2014-04-25 | | Release date: | 2015-05-20 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter.
Biochemistry, 54, 2015
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4Q4H
 | | TM287/288 in its apo state | | Descriptor: | ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288 | | Authors: | Hohl, M, Gruetter, M.G, Seeger, M.A. | | Deposit date: | 2014-04-14 | | Release date: | 2014-07-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.527 Å) | | Cite: | Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4Q7M
 | | Structure of NBD288-Avi of TM287/288 | | Descriptor: | Uncharacterized ABC transporter ATP-binding protein TM_0288 | | Authors: | Bukowska, M.A, Hohl, M, Gruetter, M.G, Seeger, M.A. | | Deposit date: | 2014-04-25 | | Release date: | 2015-05-20 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter.
Biochemistry, 54, 2015
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3G7Y
 | | Crystal structure of oxidized Ost6L | | Descriptor: | Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6 | | Authors: | Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M. | | Deposit date: | 2009-02-11 | | Release date: | 2009-06-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.215 Å) | | Cite: | Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3GA4
 | | Crystal structure of Ost6L (photoreduced form) | | Descriptor: | 1,2-ETHANEDIOL, Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6, TETRAETHYLENE GLYCOL | | Authors: | Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M. | | Deposit date: | 2009-02-16 | | Release date: | 2009-06-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3G9B
 | | Crystal structure of reduced Ost6L | | Descriptor: | Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6 | | Authors: | Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M. | | Deposit date: | 2009-02-13 | | Release date: | 2009-06-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2MJM
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2I1B
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6I9J
 | | Human transforming growth factor beta2 in a tetragonal crystal form | | Descriptor: | Transforming growth factor beta-2 proprotein | | Authors: | Gomis-Ruth, F.X, Marino-Puertas, L, del Amo-Maestro, L, Goulas, T. | | Deposit date: | 2018-11-23 | | Release date: | 2019-07-03 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor beta 2 in a new conformation.
Sci Rep, 9, 2019
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2J8S
 | | Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors | | Descriptor: | ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-ALPHA-D-MALTOSIDE, ... | | Authors: | Sennhauser, G, Amstutz, P, Briand, C, Storchenegger, O, Gruetter, M.G. | | Deposit date: | 2006-10-27 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Drug Export Pathway of Multidrug Exporter Acrb Revealed by Darpin Inhibitors.
Plos Biol., 5, 2007
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2K7Z
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1TGK
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1TGJ
 | | HUMAN TRANSFORMING GROWTH FACTOR-BETA 3, CRYSTALLIZED FROM DIOXANE | | Descriptor: | 1,4-DIETHYLENE DIOXIDE, TRANSFORMING GROWTH FACTOR-BETA 3 | | Authors: | Mittl, P.R.E, Priestle, J.P, Gruetter, M.G. | | Deposit date: | 1996-07-09 | | Release date: | 1997-01-11 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
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3N5I
 | | Crystal structure of the precursor (S250A mutant) of the N-terminal beta-aminopeptidase BapA | | Descriptor: | Beta-peptidyl aminopeptidase, GLYCEROL, SULFATE ION | | Authors: | Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G. | | Deposit date: | 2010-05-25 | | Release date: | 2011-06-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family.
Structure, 20, 2012
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3NOG
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3NOC
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3N2W
 | | Crystal structure of the N-terminal beta-aminopeptidase BapA from Sphingosinicella xenopeptidilytica | | Descriptor: | Beta-peptidyl aminopeptidase, GLYCEROL, SULFATE ION | | Authors: | Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G. | | Deposit date: | 2010-05-19 | | Release date: | 2011-06-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family.
Structure, 20, 2012
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