3CKI
| Crystal structure of the TACE-N-TIMP-3 complex | 分子名称: | ADAM 17, Metalloproteinase inhibitor 3, SODIUM ION, ... | 著者 | Wisniewska, M, Goettig, P, Maskos, K, Belouski, E, Winters, D, Hecht, R, Black, R, Bode, W. | 登録日 | 2008-03-15 | 公開日 | 2008-08-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex. J.Mol.Biol., 381, 2008
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2XO2
| Human Annexin V with incorporated Methionine analogue Azidohomoalanine | 分子名称: | ANNEXIN A5, CALCIUM ION, CHLORIDE ION, ... | 著者 | Debela, M, Merkel, L, Goettig, P, Budisa, N. | 登録日 | 2010-08-09 | 公開日 | 2011-08-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Non-Canonical Amino Acids for Click Chemistry Reactions Incorporated in Human Annexin V To be Published
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4NFE
| Human kallikrein-related peptidase 2 in complex with benzamidine | 分子名称: | BENZAMIDINE, Kallikrein-2, SULFATE ION | 著者 | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | 登録日 | 2013-10-31 | 公開日 | 2014-10-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
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4NFF
| Human kallikrein-related peptidase 2 in complex with PPACK | 分子名称: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Kallikrein-2 | 著者 | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | 登録日 | 2013-10-31 | 公開日 | 2014-10-29 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
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2QXG
| Crystal Structure of Human Kallikrein 7 in Complex with Ala-Ala-Phe-chloromethylketone | 分子名称: | Kallikrein-7, L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide | 著者 | Debela, M, Hess, P, Magdolen, V, Bode, W, Steiner, T, Goettig, P. | 登録日 | 2007-08-11 | 公開日 | 2008-01-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2QXJ
| Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone and Copper | 分子名称: | COPPER (II) ION, Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide | 著者 | Debela, M, Hess, P, Magdolen, V, Schechter, N.M, Bode, W, Goettig, P. | 登録日 | 2007-08-11 | 公開日 | 2008-01-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2QXI
| High resolution structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone | 分子名称: | Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide | 著者 | Debela, M, Hess, P, Magdolen, V, Schechter, N.M, Bode, W, Goettig, P. | 登録日 | 2007-08-11 | 公開日 | 2008-01-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2QXH
| Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone | 分子名称: | Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide | 著者 | Debela, M, Hess, P, Magdolen, V, Schechter, N.M, Bode, W, Goettig, P. | 登録日 | 2007-08-11 | 公開日 | 2008-01-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7. Proc.Natl.Acad.Sci.Usa, 104, 2007
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5MS4
| Kallikrein-related peptidase 8 leupeptin inhibitor complex | 分子名称: | CALCIUM ION, Kallikrein-8, LEUPEPTIN, ... | 著者 | Debela, M, Magdolen, V, Skala, W, Bode, W, Brandstetter, H, Goettig, P. | 登録日 | 2016-12-30 | 公開日 | 2018-01-17 | 最終更新日 | 2019-10-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin. Sci Rep, 8, 2018
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5MS3
| Kallikrein-related peptidase 8 calcium complex | 分子名称: | CALCIUM ION, Kallikrein-8 | 著者 | Debela, M, Magdolen, V, Skala, W, Bode, W, Brandstetter, H, Goettig, P. | 登録日 | 2016-12-30 | 公開日 | 2018-01-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Specificity profiles and antagonistic Ca2+ and Zn2+ regulation of human KLK8/neuropsin activity by modules identified in crystal structures To Be Published
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2BDI
| Human Kallikrein 4 complex with cobalt and p-aminobenzamidine | 分子名称: | COBALT (II) ION, Kallikrein-4, P-AMINO BENZAMIDINE | 著者 | Debela, M, Bode, W, Goettig, P, Structural Proteomics in Europe (SPINE) | 登録日 | 2005-10-20 | 公開日 | 2006-10-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site. J.Mol.Biol., 362, 2006
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2BDH
| Human Kallikrein 4 complex with zinc and p-aminobenzamidine | 分子名称: | Kallikrein-4, P-AMINO BENZAMIDINE, ZINC ION | 著者 | Debela, M, Bode, W, Goettig, P, Structural Proteomics in Europe (SPINE) | 登録日 | 2005-10-20 | 公開日 | 2006-10-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site. J.Mol.Biol., 362, 2006
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2BDG
| Human Kallikrein 4 complex with nickel and p-aminobenzamidine | 分子名称: | CHLORIDE ION, Kallikrein-4, NICKEL (II) ION, ... | 著者 | Debela, M, Bode, W, Goettig, P, Structural Proteomics in Europe (SPINE) | 登録日 | 2005-10-20 | 公開日 | 2006-10-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site. J.Mol.Biol., 362, 2006
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1Z5H
| Crystal structures of the Tricorn interacting Factor F3 from Thermoplasma acidophilum | 分子名称: | SULFATE ION, Tricorn protease interacting factor F3, ZINC ION | 著者 | Kyrieleis, O.J.P, Goettig, P, Kiefersauer, R, Huber, R, Brandstetter, H. | 登録日 | 2005-03-18 | 公開日 | 2005-06-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma acidophilum, a Zinc Aminopeptidase in Three Different Conformations J.MOL.BIOL., 349, 2005
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2OW0
| MMP-9 active site mutant with iodine-labeled carboxylate inhibitor | 分子名称: | CALCIUM ION, CHLORIDE ION, Matrix metalloproteinase-9 (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB), ... | 著者 | Tochowicz, A, Bode, W, Maskos, K, Goettig, P. | 登録日 | 2007-02-15 | 公開日 | 2007-06-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side-chain to Selectivity. J.Mol.Biol., 371, 2007
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2OVX
| MMP-9 active site mutant with barbiturate inhibitor | 分子名称: | 5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE, CALCIUM ION, CHLORIDE ION, ... | 著者 | Tochowicz, A, Bode, W, Maskos, K, Goettig, P. | 登録日 | 2007-02-15 | 公開日 | 2007-06-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side-chain to Selectivity. J.Mol.Biol., 371, 2007
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2OW2
| MMP-9 active site mutant with difluoro butanoic acid inhibitor | 分子名称: | (3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Tochowicz, A, Bode, W, Maskos, K, Goettig, P. | 登録日 | 2007-02-15 | 公開日 | 2007-06-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side-chain to Selectivity. J.Mol.Biol., 371, 2007
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2OW1
| MMP-9 active site mutant with trifluoromethyl hydroxamate inhibitor | 分子名称: | (2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE, CALCIUM ION, CHLORIDE ION, ... | 著者 | Tochowicz, A, Bode, W, Maskos, K, Goettig, P. | 登録日 | 2007-02-15 | 公開日 | 2007-06-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side-chain to Selectivity. J.Mol.Biol., 371, 2007
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2OVZ
| MMP-9 active site mutant with phosphinate inhibitor | 分子名称: | CALCIUM ION, CHLORIDE ION, Matrix metalloproteinase-9 (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB), ... | 著者 | Tochowicz, A, Bode, W, Maskos, K, Goettig, P. | 登録日 | 2007-02-15 | 公開日 | 2007-06-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side-chain to Selectivity. J.Mol.Biol., 371, 2007
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1Z1W
| Crystal structures of the tricorn interacting facor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations | 分子名称: | SULFATE ION, Tricorn protease interacting factor F3, ZINC ION | 著者 | Kyrieleis, O.J.P, Goettig, P, Kiefersauer, R, Huber, R, Brandstetter, H. | 登録日 | 2005-03-07 | 公開日 | 2005-05-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma acidophilum, a Zinc Aminopeptidase in Three Different Conformations J.MOL.BIOL., 394, 2005
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2N52
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